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AZD7507

AZD7507 Structure
AZD7507 structure
CAS No.
1041852-85-0
Chemical Name:
AZD7507
Synonyms
AZD7507;CS-2850;AZD7507, 10 mM in DMSO;AZD7507; AZD-7507; AZD 7507;1041852-85-0;4-(2-fluoro-4-methylanilino)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide;3-Cinnolinecarboxamide, 4-[(2-fluoro-4-methylphenyl)amino]-6-[4-(2-hydroxyethyl)-1-piperazinyl]-7-methoxy-;AZD7507,AZD 7507,Inhibitor,AZD-7507,CSF-1R,CSF1R,CSF-1 receptor,c-Fms,inhibit,colony stimulating factor 1 receptor
CBNumber:
CB34804162
Molecular Formula:
C23H27FN6O3
Molecular Weight:
454.5
MDL Number:
MOL File:
1041852-85-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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AZD7507 Properties

Boiling point 680.7±65.0 °C(Predicted)
Density 1.346±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 14.47±0.30(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

AZD7507 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 37485 AZD 7507 ≥98% 1041852-85-0 1mg $44 2026-04-30 Buy
Cayman Chemical 37485 AZD 7507 ≥98% 1041852-85-0 5mg $198 2026-04-30 Buy
Cayman Chemical 37485 AZD 7507 ≥98% 1041852-85-0 10mg $351 2026-04-30 Buy
Cayman Chemical 37485 AZD 7507 ≥98% 1041852-85-0 25mg $767 2026-04-30 Buy
Biosynth RRB85285 AZD7507 1041852-85-0 10mg $1031.1 2026-06-05 Buy
Product number Packaging Price Buy
37485 1mg $44 Buy
37485 5mg $198 Buy
37485 10mg $351 Buy
37485 25mg $767 Buy
RRB85285 10mg $1031.1 Buy

AZD7507 Chemical Properties,Uses,Production

Uses

AZD7507 is a potent and orally active CSF-1R inhibitor, with antitumor activity.

in vivo

AZD7507 has good rat oral PK, with in vivo clearance of 7 mL/min/kg and 42% bioavailability. In the canine L-type Ca channel assay, the IC50 is >20 μM[1]. AZD7507 significantly decreases the number of CD68+ macrophages in mice, and also reduces the volume and mass in mice bearing CC-LP-1 and SNU-1079 cells, but not WITT-1 cells[2].

References

[1] Scott DA, et al. Mitigation of cardiovascular toxicity in a series of CSF-1R inhibitors, and the identification of AZD7507. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4591-6. DOI:10.1016/j.bmcl.2013.06.031
[2] Boulter L, et al. WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited. Send to J Clin Invest. 2015 Mar 2;125(3):1269-85. DOI:10.1172/JCI76452

AZD7507 Preparation Products And Raw materials

Raw materials

Preparation Products

AZD7507 Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4861 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 10000 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
InvivoChem +1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6288 58
Cckinase, Inc. +1 (732)236-3202 sales@cckinase.com United States 2728 58
Supplier Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai SuperLan Chemcial Technique Centre 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
InvivoChem 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 58
Cckinase, Inc. 58

View Lastest Price from AZD7507 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AZD7507 pictures 2026-07-27 AZD7507
1041852-85-0
 $48.00-173.00 99.55% 10g TargetMol Chemicals Inc.
AZD7507 pictures 2026-07-27 AZD7507
1041852-85-0
 $48.00-173.00 99.55% 10g TargetMol Chemicals Inc.
  • AZD7507 pictures
  • AZD7507
    1041852-85-0
  • $48.00-173.00
  • 99.55%
  • TargetMol Chemicals Inc.
  • AZD7507 pictures
  • AZD7507
    1041852-85-0
  • $48.00-173.00
  • 99.55%
  • TargetMol Chemicals Inc.

AZD7507 Spectrum

AZD7507(1041852-85-0)1HNMR

1041852-85-0(AZD7507)Related Search:

1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)- 5-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-3-acetamide dihydrochloride Ripretinib 1-(4-(5-(5-amino-6-(5-(tert-butyl)-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1H-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one Chk2 Inhibitor
CSF1R Protein, HUMAN (HEK293, HIS-FC)

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AZD7507 AZD7507; AZD-7507; AZD 7507;1041852-85-0 CS-2850 4-(2-fluoro-4-methylanilino)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide 3-Cinnolinecarboxamide, 4-[(2-fluoro-4-methylphenyl)amino]-6-[4-(2-hydroxyethyl)-1-piperazinyl]-7-methoxy- AZD7507,AZD 7507,Inhibitor,AZD-7507,CSF-1R,CSF1R,CSF-1 receptor,c-Fms,inhibit,colony stimulating factor 1 receptor AZD7507, 10 mM in DMSO 1041852-85-0 C23H27FN6O3