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Norbinaltorphimine Dihydrochloride

Norbinaltorphimine Dihydrochloride Structure
Norbinaltorphimine Dihydrochloride structure
CAS No.
113158-34-2
Chemical Name:
Norbinaltorphimine Dihydrochloride
Synonyms
nor-Binaltorphimine dihydrochloride;nor-Binaltorphimine (nor-BNI), kappa opioid receptor antagonist;(1S,2S,7S,8S,12R,20R,24R,32R)-11,33-bis(cyclopropylmethyl)-19,25-dioxa-11,22,33-triazaundecacyclo[24.9.1.18,14.01,24.02,32.04,23.05,21.07,12.08,20.030,36.018,37]heptatriaconta-4(23),5(21),14(37),15,17,26,28,30(36)-octaene-2,7,17,27-tetrol
CBNumber:
CB34806515
Molecular Formula:
C40H44ClN3O6
Molecular Weight:
698.26
MDL Number:
MOL File:
113158-34-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-30 11:39:11
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Norbinaltorphimine Dihydrochloride Properties

Melting point >280 °C (decomp)
storage temp. Store at RT
solubility Soluble to 25 mM in water with gentle warming and to 25 mM in DMSO
form Powder
color Light yellow to gray
InChIKey JOJPJLHRMGPDPV-LZQROVCBSA-N
SMILES Cl[H].Cl[H].Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)c6[nH]c7[C@@H]8Oc9c(O)ccc%10C[C@H]%11N(CC[C@@]8(c9%10)[C@@]%11(O)Cc7c6C[C@@]35O)CC%12CC%12)CC%13CC%13
FDA UNII Y8WNP37PIV
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

Norbinaltorphimine Dihydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N1771 nor-Binaltorphimine dihydrochloride 113158-34-2 10MG $200 2026-04-30 Buy
Usbiological 460883 Norbinaltorphimine Dihydrochloride Salt 113158-34-2 10mg $468 2026-06-03 Buy
Usbiological 460883 Norbinaltorphimine Dihydrochloride Salt 113158-34-2 100mg $2654 2026-06-03 Buy
Biosynth NEA15834 Norbinaltorphimine dihydrochloride 113158-34-2 1mg $900 2026-06-04 Buy
Biosynth NEA15834 Norbinaltorphimine dihydrochloride 113158-34-2 10mg $900 2026-06-04 Buy
Product number Packaging Price Buy
N1771 10MG $200 Buy
460883 10mg $468 Buy
460883 100mg $2654 Buy
NEA15834 1mg $900 Buy
NEA15834 10mg $900 Buy

Norbinaltorphimine Dihydrochloride Chemical Properties, Uses, Production

Uses

Norbinaltorphimine Dihydrochloride Salt is a synthetic derivative of Naltrexone (N285750, HCl) and is useful as a κ-opioid antagonist.

Biological Activity

Highly selective k-opioid receptor antagonist. nor-Binaltorphimine has antidepressant properties.

in vivo

Norbinaltorphimine has weak and inconsistent effects on THC-induced taste avoidance in adolescent rats in that Norbinaltorphimine both attenuates and strengthens taste avoidance dependent on dose and trial. Norbinaltorphimine has limited impact on the final one-bottle avoidance and no effects on the two-bottle preference test. Interestingly, Norbinaltorphimine has no effect on THC-induced taste avoidance in adult rats as well[2]. Norbinaltorphimine pretreatment significantly attenuates stress-induced reinstatement of nicotine-CPP, but has no effect on nicotine-primed reinstatement[3].

IC 50

κ Opioid Receptor/KOR

Norbinaltorphimine Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Norbinaltorphimine Dihydrochloride Suppliers

Global Suppliers ( 25)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10233 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5985 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
Supplier Advantage
BOC Sciences 65
Shanghai EFE Biological Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Energy Chemical 58
cjbscvictory 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai Amole Biotechnology Co., Ltd. 58

View Latest Price from Norbinaltorphimine Dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Norbinaltorphimine dihydrochloride pictures 2026-08-30 Norbinaltorphimine dihydrochloride
113158-34-2
 $32.00-77.00 99.88% 10g TargetMol Chemicals Inc.
Norbinaltorphimine dihydrochloride pictures 2026-07-15 Norbinaltorphimine dihydrochloride
113158-34-2
 $32.00-77.00 99.88% 10g TargetMol Chemicals Inc.

Norbinaltorphimine Dihydrochloride Spectrum

Norbinaltorphimine Dihydrochloride(113158-34-2)1HNMR

113158-34-2 (Norbinaltorphimine Dihydrochloride) Related Search:

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(1S,2S,7S,8S,12R,20R,24R,32R)-11,33-bis(cyclopropylmethyl)-19,25-dioxa-11,22,33-triazaundecacyclo[24.9.1.18,14.01,24.02,32.04,23.05,21.07,12.08,20.030,36.018,37]heptatriaconta-4(23),5(21),14(37),15,17,26,28,30(36)-octaene-2,7,17,27-tetrol nor-Binaltorphimine (nor-BNI), kappa opioid receptor antagonist nor-Binaltorphimine dihydrochloride 113158-34-2