HO-2 (human recombinant)
- CAS No.
- Chemical Name:
- HO-2 (human recombinant)
- Synonyms
- HO-2 (human recombinant)
- CBNumber:
- CB34814701
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
HO-2 (human recombinant) price More Price(1)
HO-2 (human recombinant) Chemical Properties, Uses, Production
Description
Heme oxygenase-2 (HO-2) is a constitutively active heme oxygenase encoded by the HMOX2 gene. It is a membrane-bound enzyme that catalyzes the cleavage of heme to give carbon monoxide (CO), ferrous ions (Fe2+), and biliverdin, with biliverdin being further processed into bilirubin. HO-2 is found in neurons, testes, and endothelial and smooth muscle cells from cerebral vessels. HO-2 protects against apoptotic neuronal cell death in models of ischemic injury and oxidative stress. It also acts as an oxygen sensor to inhibit systemic vascular reactivity and reduce cell death in response to hypoxia.
References
[1] MAINES M D. The heme oxygenase system: a regulator of second messenger gases.[J]. Annual review of pharmacology and toxicology, 1997, 37: 517-554. DOI: 10.1146/annurev.pharmtox.37.1.517
[2] JORGE MUOZ-SáNCHEZ M E C C. A review on hemeoxygenase-2: focus on cellular protection and oxygen response.[J]. Oxidative Medicine and Cellular Longevity, 2014, 2014: 604981. DOI: 10.1155/2014/604981
HO-2 (human recombinant) Preparation Products And Raw materials
Raw materials
Preparation Products
HO-2 (human recombinant) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Supplier | Advantage |
|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
