ChemicalBook >> CAS DataBase List >>(2-CHLORO-PYRIDIN-4-YL)-METHANOL

(2-CHLORO-PYRIDIN-4-YL)-METHANOL

(2-CHLORO-PYRIDIN-4-YL)-METHANOL structure

CAS No.: 100704-10-7

Chemical Name:: (2-CHLORO-PYRIDIN-4-YL)-METHANOL

Synonyms: oro-4-pyridinyL;BUTTPARK 154\50-15;2-Chloro-4-pyridinemethanol;(2-chloro-4-pyridyl)methanol;4-Pyridinemethanol, 2-chloro-;(2-CHLORO-4-PYRIDINYL)METHANOL;2-Chloropyridine-4-methanol,97%;2-Chloro-4-pyridinemethanol >(2-CHLORO-PYRIDIN-4-YL)-METHANOL;2-CHLORO-4-HYDROXYMETHYLPYRIDINE

CBNumber:: CB3487787

Molecular Formula:: C6H6ClNO

Molecular Weight:: 143.57

MDL Number:: MFCD06858767

MOL File:: 100704-10-7.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:41

Request For Quotation

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Properties

Melting point	65.5 °C
Boiling point	279.0±25.0 °C(Predicted)
Density	1.324±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	soluble in Methanol
form	powder to crystal
pka	13.08±0.10(Predicted)
color	White to Light yellow
λmax	262nm(MeOH)(lit.)
CAS DataBase Reference	100704-10-7(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

Hazard Codes

Xi,Xn

Risk Statements

22-36/37/38

Safety Statements

26-28-45

WGK Germany

Hazard Note

Harmful

HazardClass

IRRITANT

HS Code

2933399990

NFPA 704

	1
2		0

(2-CHLORO-PYRIDIN-4-YL)-METHANOL price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	714445	(2-Chloro-4-pyridinyl)methanol 97%	100704-10-7	250mg	$40.8	2023-01-07	Buy
TCI Chemical	C2595	2-Chloro-4-pyridinemethanol >96.0%(GC)(T)	100704-10-7	1g	$159	2024-03-01	Buy
TRC	C596193	(2-Chloropyridin-4-yl)methanol	100704-10-7	10mg	$45	2021-12-16	Buy
Matrix Scientific	024833	(2-Chloro-4-pyridinyl)methanol 97%	100704-10-7	1g	$19	2021-12-16	Buy
Matrix Scientific	024833	(2-Chloro-4-pyridinyl)methanol 97%	100704-10-7	500mg	$12	2021-12-16	Buy

Product number	Packaging	Price	Buy
714445	250mg	$40.8	Buy
C2595	1g	$159	Buy
C596193	10mg	$45	Buy
024833	1g	$19	Buy
024833	500mg	$12	Buy

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Chemical Properties,Uses,Production

Uses

(2-chloro-4-pyridinyl)methanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Definition

ChEBI: (2-Chloro-4-pyridinyl)methanol is a member of pyridines and an organohalogen compound.

Synthesis

58481-11-1

100704-10-7

The general procedure for the synthesis of 2-chloro-4-hydroxymethylpyridine from methyl 2-chloropyridine-4-carboxylate was as follows: 2-chloropyridine-4-methanol (reference Compound No. 7-1) was prepared with reference to Example 7. Under nitrogen protection, 0.95 M hexane solution of hydrogenated diisobutylaluminum (200 mL, 190 mmol) was slowly added dropwise to a solution of anhydrous tetrahydrofuran (300 mL) containing methyl 2-chloropyridine-4-carboxylate (11 g, 62 mmol), and the reaction mixture was stirred for 2 hr. under the cooling of an ice bath. Subsequently, 1N hydrochloric acid (200 mL) was added to the reaction system and stirring was continued for 1 hour at room temperature. Upon completion of the reaction, saturated aqueous sodium bicarbonate solution (400 mL) was added to neutralize and then extracted three times with ethyl acetate (100 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated under reduced pressure to remove the solvent to give 8.5 g of white solid 2-chloro-4-hydroxymethylpyridine in 95% yield. The structure of the product was confirmed by 1H-NMR (500 MHz, DMSO-d6): δ 4.56 (d, J = 5.8 Hz, 2H), 5.54 (t, J = 5.8 Hz, 1H), 7.34 (d, J = 4.9 Hz, 1H), 7.41 (s, 1H), 8.34 (d, J = 4.9 Hz, 1H).

References

[1] Patent: EP1602647, 2005, A1. Location in patent: Page/Page column 48
[2] Patent: WO2008/11478, 2008, A2. Location in patent: Page/Page column 76-77
[3] Patent: WO2017/42643, 2017, A1. Location in patent: Page/Page column 25
[4] Patent: WO2006/96338, 2006, A1. Location in patent: Page/Page column 47
[5] Patent: WO2006/2383, 2006, A2. Location in patent: Page/Page column 55

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Preparation Products And Raw materials

Raw materials

2-Chloro-4-pyridinecarboxylic acid METHYL 2-CHLOROISONICOTINATE Sodium bicarbonate Diisobutylaluminium hydride Hexane

Hydrochloric acid Water Tetrahydrofuran

1of2

Preparation Products

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Suppliers

Global( 281)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29733	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
Suzhou Ryan Pharmachem Technology Co.,Ltd.	+86-512-68780025 +8618962125825	sales@ryanchem.com	China	136	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Nanjing Fred Technology Co., Ltd.	+86-02584696168 15380713688	Austin@fredchem.cn	CHINA	865	58

Supplier	Advantage
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Suzhou Ryan Pharmachem Technology Co.,Ltd.	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Nanjing Fred Technology Co., Ltd.	58

View Lastest Price from (2-CHLORO-PYRIDIN-4-YL)-METHANOL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-08	(2-Chloro-4-pyridinyl)Methanol 100704-10-7	US $0.00-0.00 / Kg/Drum	1KG	98%min	500kgs	WUHAN FORTUNA CHEMICAL CO., LTD
2025-04-04	2-Chloro-4-(Hydroxymethyl)Pyridine 100704-10-7	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-09-03	(2-CHLORO-PYRIDIN-4-YL)-METHANOL 100704-10-7	US $1.10 / g	1g	99.00%	100 Tons min	Dideu Industries Group Limited

(2-Chloro-4-pyridinyl)Methanol
100704-10-7
US $0.00-0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

2-Chloro-4-(Hydroxymethyl)Pyridine
100704-10-7
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

(2-CHLORO-PYRIDIN-4-YL)-METHANOL
100704-10-7
US $1.10 / g
99.00%
Dideu Industries Group Limited

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Spectrum

(2-CHLORO-PYRIDIN-4-YL)-METHANOL(100704-10-7)¹HNMR

100704-10-7((2-CHLORO-PYRIDIN-4-YL)-METHANOL)Related Search:

3-IODO-2-PROPOXY-PYRIDINE 2-CHLOROQUINOLINE-4-CARBOXYLIC ACID 2-(CYCLOHEXYLOXY)-3-IODOPYRIDINE (2-CHLORO-PYRIDIN-4-YL)-METHANOL METHYL 2,6-DICHLOROISONICOTINATE

3-IODO-2-(2,2,2-TRIFLUORO-ETHOXY)-PYRIDINE 2-CYCLOPROPYLMETHOXY-3-IODO-PYRIDINE ETHYL 2-CHLORO-3-CYANO-6-METHYLISONICOTINATE 6-BROMO-2-CHLOROQUINOLINE-4-CARBOXYLIC ACID, 97 2-Chloro-6-methylpyridine-4-carboxylic acid

3,5-BIS(METHYLSULFONYL)ANILINE 2-ISOPROPOXY-3-IODO-PYRIDINE 2-(CYCLOPENTYLOXY)-3-IODOPYRIDINE (2-CHLORO-PYRIDIN-3-YL)-METHANOL (4-Chloro-pyridin-3-yl)-methanol

(4-CHLORO-PYRIDIN-2-YL)-METHANOL (5-Chloro-pyridin-3-yl)-methanol (6-CHLORO-PYRIDIN-2-YL)-METHANOL

1of4

(2-CHLORO-PYRIDIN-4-YL)-METHANOL (2-CHLORO-PYRIDINE-4-YL)-METHANOL 2-CHLORO-4-HYDROXYMETHYLPYRIDINE (2-CHLORO-4-PYRIDINYL)METHANOL BUTTPARK 154\50-15 2-Chloro-4-(hydroxymethyl)pyridine 97% 4-Pyridinemethanol,2-chloro-(6CI,9CI) 2-Chloro-4-pyridinemethanol 2-Chloropyridine-4-methanol,97% (2-chloro-4-pyridyl)methanol (2-chloro-4-pyridinyl)methanol(SALTDATA: FREE) 2-Chloro-4-pyridinemethanol > oro-4-pyridinyL 4-Pyridinemethanol, 2-chloro- (2-CHLORO-PYRIDIN-4-YL)-METHANOL ISO 9001：2015 REACH 100704-10-7 1450-83-7 Pyridines PYRIDINE pharmacetical