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ChemicalBook >> CAS DataBase List >>(2-CHLORO-PYRIDIN-4-YL)-METHANOL

(2-CHLORO-PYRIDIN-4-YL)-METHANOL

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Structure
(2-CHLORO-PYRIDIN-4-YL)-METHANOL structure
CAS No.
100704-10-7
Chemical Name:
(2-CHLORO-PYRIDIN-4-YL)-METHANOL
Synonyms
oro-4-pyridinyL;BUTTPARK 154\50-15;2-Chloro-4-pyridinemethanol;(2-chloro-4-pyridyl)methanol;4-Pyridinemethanol, 2-chloro-;(2-CHLORO-4-PYRIDINYL)METHANOL;2-Chloropyridine-4-methanol,97%;2-Chloro-4-pyridinemethanol >(2-CHLORO-PYRIDIN-4-YL)-METHANOL;2-CHLORO-4-HYDROXYMETHYLPYRIDINE
CBNumber:
CB3487787
Molecular Formula:
C6H6ClNO
Molecular Weight:
143.57
MDL Number:
MFCD06858767
MOL File:
100704-10-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:10:31
Product description Number Pack Size Price
(2-Chloro-4-pyridinyl)methanol 97% 714445 250mg $40.8
2-Chloro-4-pyridinemethanol >96.0%(GC)(T) C2595 1g $159
(2-CHLOROPYRIDIN-4-YL)METHANOL 97% CL0096 1G $24
(2-CHLOROPYRIDIN-4-YL)METHANOL 97% CL0096 5G $75
(2-CHLOROPYRIDIN-4-YL)METHANOL 97% CL0096 25G $345
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(2-CHLORO-PYRIDIN-4-YL)-METHANOL Properties

Melting point 65.5 °C
Boiling point 279.0±25.0 °C(Predicted)
Density 1.324±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility soluble in Methanol
form powder to crystal
pka 13.08±0.10(Predicted)
color White to Light yellow
λmax 262nm(MeOH)(lit.)
InChI 1S/C6H6ClNO/c7-6-3-5(4-9)1-2-8-6/h1-3,9H,4H2
InChIKey UDDVPFLXGOBESH-UHFFFAOYSA-N
SMILES OCc1ccnc(Cl)c1
CAS DataBase Reference 100704-10-7(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
target organs Respiratory system
Hazard Codes  Xi,Xn
Risk Statements  22-36/37/38
Safety Statements  26-28-45
WGK Germany  3
Hazard Note  Harmful
HazardClass  IRRITANT
HS Code  2933399990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

(2-CHLORO-PYRIDIN-4-YL)-METHANOL price More Price(96)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 714445 (2-Chloro-4-pyridinyl)methanol 97% 100704-10-7 250mg $40.8 2023-01-07 Buy
TCI Chemical C2595 2-Chloro-4-pyridinemethanol >96.0%(GC)(T) 100704-10-7 1g $159 2024-03-01 Buy
AstaTech CL0096 (2-CHLOROPYRIDIN-4-YL)METHANOL 97% 100704-10-7 1G $24 2026-04-30 Buy
AstaTech CL0096 (2-CHLOROPYRIDIN-4-YL)METHANOL 97% 100704-10-7 5G $75 2026-04-30 Buy
AstaTech CL0096 (2-CHLOROPYRIDIN-4-YL)METHANOL 97% 100704-10-7 25G $345 2026-04-30 Buy
Product number Packaging Price Buy
714445 250mg $40.8 Buy
C2595 1g $159 Buy
CL0096 1G $24 Buy
CL0096 5G $75 Buy
CL0096 25G $345 Buy

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Chemical Properties,Uses,Production

Uses

(2-chloro-4-pyridinyl)methanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Definition

ChEBI: (2-Chloro-4-pyridinyl)methanol is a member of pyridines and an organohalogen compound.

Synthesis

METHYL 2-CHLOROISONICOTINATE

58481-11-1

(2-CHLORO-PYRIDIN-4-YL)-METHANOL

100704-10-7

The general procedure for the synthesis of 2-chloro-4-hydroxymethylpyridine from methyl 2-chloropyridine-4-carboxylate was as follows: 2-chloropyridine-4-methanol (reference Compound No. 7-1) was prepared with reference to Example 7. Under nitrogen protection, 0.95 M hexane solution of hydrogenated diisobutylaluminum (200 mL, 190 mmol) was slowly added dropwise to a solution of anhydrous tetrahydrofuran (300 mL) containing methyl 2-chloropyridine-4-carboxylate (11 g, 62 mmol), and the reaction mixture was stirred for 2 hr. under the cooling of an ice bath. Subsequently, 1N hydrochloric acid (200 mL) was added to the reaction system and stirring was continued for 1 hour at room temperature. Upon completion of the reaction, saturated aqueous sodium bicarbonate solution (400 mL) was added to neutralize and then extracted three times with ethyl acetate (100 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated under reduced pressure to remove the solvent to give 8.5 g of white solid 2-chloro-4-hydroxymethylpyridine in 95% yield. The structure of the product was confirmed by 1H-NMR (500 MHz, DMSO-d6): δ 4.56 (d, J = 5.8 Hz, 2H), 5.54 (t, J = 5.8 Hz, 1H), 7.34 (d, J = 4.9 Hz, 1H), 7.41 (s, 1H), 8.34 (d, J = 4.9 Hz, 1H).

References

[1] Patent: EP1602647, 2005, A1. Location in patent: Page/Page column 48
[2] Patent: WO2008/11478, 2008, A2. Location in patent: Page/Page column 76-77
[3] Patent: WO2017/42643, 2017, A1. Location in patent: Page/Page column 25
[4] Patent: WO2006/96338, 2006, A1. Location in patent: Page/Page column 47
[5] Patent: WO2006/2383, 2006, A2. Location in patent: Page/Page column 55

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Preparation Products And Raw materials

Raw materials

2-Chloro-4-pyridinecarboxylic acid METHYL 2-CHLOROISONICOTINATE Sodium bicarbonate Diisobutylaluminium hydride Hexane
Hydrochloric acid Water Tetrahydrofuran

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Preparation Products

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Suppliers

Global( 283)Suppliers
Supplier Tel Email Country ProdList Advantage
Frapp's ChemicalNFTZ Co., Ltd. 		+86 (576) 8169-6106 sales@frappschem.com China 880 50
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Nanjing Fred Technology Co., Ltd. 		+86-02584696168 15380713688 Austin@fredchem.cn CHINA 865 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14304 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		+8617735180244 mike_yan@xuanranglobal.com CHINA 4017 58
Supplier Advantage
Frapp's ChemicalNFTZ Co., Ltd. 		50
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Nanjing Fred Technology Co., Ltd. 		58
Win-Win chemical CO., Limited 		58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		58

View Lastest Price from (2-CHLORO-PYRIDIN-4-YL)-METHANOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(2-Chloro-4-pyridinyl)Methanol pictures 2026-06-05 (2-Chloro-4-pyridinyl)Methanol
100704-10-7
 1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
(2-CHLORO-PYRIDIN-4-YL)-METHANOL pictures 2025-11-18 (2-CHLORO-PYRIDIN-4-YL)-METHANOL
100704-10-7
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Chloro-4-(Hydroxymethyl)Pyridine pictures 2025-04-04 2-Chloro-4-(Hydroxymethyl)Pyridine
100704-10-7
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Spectrum

(2-CHLORO-PYRIDIN-4-YL)-METHANOL(100704-10-7)1HNMR

100704-10-7((2-CHLORO-PYRIDIN-4-YL)-METHANOL)Related Search:

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3-IODO-2-(2,2,2-TRIFLUORO-ETHOXY)-PYRIDINE 2-CYCLOPROPYLMETHOXY-3-IODO-PYRIDINE ETHYL 2-CHLORO-3-CYANO-6-METHYLISONICOTINATE 6-BROMO-2-CHLOROQUINOLINE-4-CARBOXYLIC ACID, 97 2-Chloro-6-methylpyridine-4-carboxylic acid
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(2-CHLORO-PYRIDIN-4-YL)-METHANOL (2-CHLORO-PYRIDINE-4-YL)-METHANOL 2-CHLORO-4-HYDROXYMETHYLPYRIDINE (2-CHLORO-4-PYRIDINYL)METHANOL BUTTPARK 154\50-15 2-Chloro-4-(hydroxymethyl)pyridine 97% 4-Pyridinemethanol,2-chloro-(6CI,9CI) 2-Chloro-4-pyridinemethanol 2-Chloropyridine-4-methanol,97% (2-chloro-4-pyridyl)methanol (2-chloro-4-pyridinyl)methanol(SALTDATA: FREE) 2-Chloro-4-pyridinemethanol > oro-4-pyridinyL 4-Pyridinemethanol, 2-chloro- (2-CHLORO-PYRIDIN-4-YL)-METHANOL ISO 9001：2015 REACH 100704-10-7 1450-83-7 Pyridines PYRIDINE pharmacetical