Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
- CAS No.
- 534615-50-4
- Chemical Name:
- Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
- Synonyms
- Dec-RVRK-CMK;DECANOYL-ARG-VAL-ARG-LYS-CMK;Decanoyl-Arg-Val-Arg-Lys-chloromethylketone;L-Argininamide, N2-(1-oxodecyl)-L-arginyl-L-valyl-N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]-
- CBNumber:
- CB3491450
- Molecular Formula:
- C34H66ClN11O5
- Molecular Weight:
- 744.41
- MDL Number:
- MFCD02259677
- MOL File:
- Mol file
- TDS File:
- TDS
Decanoyl-Arg-Val-Arg-Lys-chloromethylketone price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FD111052 | Decanoyl-Arg-Val-Arg-Lys-chloromethylketone | 534615-50-4 | 2000ug | $900 | 2026-06-04 | Buy |
| Biosynth | FD111052 | Decanoyl-Arg-Val-Arg-Lys-chloromethylketone | 534615-50-4 | 1000ug | $900 | 2026-06-04 | Buy |
| Biosynth | FD111052 | Decanoyl-Arg-Val-Arg-Lys-chloromethylketone | 534615-50-4 | 500ug | $900 | 2026-06-04 | Buy |
| Biosynth | FD111052 | Decanoyl-Arg-Val-Arg-Lys-chloromethylketone | 534615-50-4 | 5000ug | $1600 | 2026-06-04 | Buy |
| Biosynth | FD111052 | Decanoyl-Arg-Val-Arg-Lys-chloromethylketone | 534615-50-4 | 10000ug | $2700 | 2026-06-04 | Buy |
Decanoyl-Arg-Val-Arg-Lys-chloromethylketone Chemical Properties, Uses, Production
Uses
DEC-RVRK-CMK (Decanoyl-Arg-Val-Arg-Lys-chloromethylketone) is a peptide-based CMK (chloromethylketone) inhibitor that targets and inactivates the secreted soluble kexin (Kex2) (Ki=8.45 μM). The yeast enzyme Kex2 (kexin, EC 3.4.21.61) is a calcium-dependent transmembrane protease and belongs to the mammalian protease family of the serine protease subtilisin family. The binding mechanism of Kex2 with different CMK inhibitors depends on substrate selectivity, particularly the selective differences between lysine and arginine at the P1 position[1].
References
[1] Wheatley JL, et al. Differential P1 arginine and lysine recognition in the prototypical proprotein convertase Kex2. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6626-31. DOI:10.1073/pnas.0701983104
Decanoyl-Arg-Val-Arg-Lys-chloromethylketone Preparation Products And Raw materials
Raw materials
Preparation Products
Decanoyl-Arg-Val-Arg-Lys-chloromethylketone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| Nanchang Tianzhen Biotechnology Co., Ltd | 13758194781 13173652190 | 522013271@qq.com | China | 2436 | 58 |
| Nanjing TGpeptide Biotechnology Co.,Ltd. | 18115476705 | sales@tgpeptide.com | China | 3058 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 29717 | 58 |
