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ADENOSINE AMINE CONGENER (ADAC)

CAS No.
96760-69-9
Chemical Name:
ADENOSINE AMINE CONGENER (ADAC)
Synonyms
ADENOSINE AMINE CONGENER (ADAC);Adenosine amine congener hydrate;Adenosine amine congener, 10 mM in DMSO;N-[4-[2-[[4-[2-[(2-Aminoethyl)amino]-2-oxoethyl]phenyl]amino]-2-oxoethyl]phenyl]adenosine;Adenosine, N-[4-[2-[[4-[2-[(2-aminoethyl)amino]-2-oxoethyl]phenyl]amino]-2-oxoethyl]phenyl]-;N6-[4-[[[4-[[[(2-AMinoethyl)aMino]carbonyl]Methyl]-anilino]carbonyl]Methyl]phenyl]adenosine hydrate;ADAC, N6-[4-[[[4-[[[(2-Aminoethyl)amino]carbonyl]methyl]-anilino]carbonyl]methyl]phenyl]adenosine hydrate;N-(2-aminoethyl)-2-(4-{2-[4-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-6-yl}amino)phenyl]acetamido}phenyl)acetamide;N-(2-Aminoethyl)-2-(4-(2-(4-((9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)amino)phenyl)acetamido)phenyl)acetamide;P1 receptor,otoprotective,Adenosine amine congener,Adenosine Receptor,loss,hearing,Inhibitor,apoptotic,injury,systemic,A1-adenosine,Cochlear,inhibit,Ca2+,neuroprotective
CBNumber:
CB3497841
Molecular Formula:
C28H32N8O6
Molecular Weight:
576.6
MDL Number:
MFCD11045962
MOL File:
96760-69-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-21 17:10:26
Product description Number Pack Size Price
Adenosine amine congener hydrate solid, ≥98% (HPLC) A111 25mg $737
Adenosine amine congener hydrate solid, ≥98% (HPLC) A111 5mg $188
Adenosine amine congener ≥98% 34394 1mg $69
Adenosine amine congener ≥98% 34394 5mg $233
Adenosine amine congener ≥98% 34394 10mg $427
More product size

ADENOSINE AMINE CONGENER (ADAC) Properties

Density 1.56±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility 0.1 M acetic acid: 12 mM
form solid
pka 13.11±0.70(Predicted)
color white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  22-24/25
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3

ADENOSINE AMINE CONGENER (ADAC) price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A111 Adenosine amine congener hydrate solid, ≥98% (HPLC) 96760-69-9 25mg $737 2023-01-07 Buy
Sigma-Aldrich A111 Adenosine amine congener hydrate solid, ≥98% (HPLC) 96760-69-9 5mg $188 2022-05-15 Buy
Cayman Chemical 34394 Adenosine amine congener ≥98% 96760-69-9 1mg $69 2026-04-30 Buy
Cayman Chemical 34394 Adenosine amine congener ≥98% 96760-69-9 5mg $233 2026-04-30 Buy
Cayman Chemical 34394 Adenosine amine congener ≥98% 96760-69-9 10mg $427 2026-04-30 Buy
Product number Packaging Price Buy
A111 25mg $737 Buy
A111 5mg $188 Buy
34394 1mg $69 Buy
34394 5mg $233 Buy
34394 10mg $427 Buy

ADENOSINE AMINE CONGENER (ADAC) Chemical Properties,Uses,Production

Uses

Adenosine amine congener (ADAC) is a selective A1 adenosine receptor agonist, can ameliorate noise- and Cisplatin-induced cochlear injury. Adenosine amine congener also has neuroprotective effects[1][2].

in vivo

Adenosine amine congener (25-300μg/kg/day; intraperitoneal injection; daily; for 5 days; male Wistar rats) treatment is most effective in the first 24 hours after noise exposure at doses >50μg/kg, providing up to 21dB protection. Adenosine amine congener mitigates noise-induced hearing loss in a dose- and time-dependent manner[1].

Animal Model:Male Wistar rats (8-10 weeks old) treated with noise exposure[1]
Dosage:25 μg/kg/day, 50 μg/kg/day, 100 μg/kg/day, 200 μg/kg/day, and 300μg/kg/day
Administration:Intraperitoneal injection; daily; for 5 days
Result:Most effective in the first 24 hours after noise exposure at doses >50μg/kg, and provided up to 21dB protection (averaged across 8-28kHz).

References

[1] Vlajkovic SM, et al. Adenosine amine congener as a cochlear rescue agent. Biomed Res Int. 2014;2014:841489. DOI:10.1155/2014/841489
[2] Vlajkovic SM, et al. Adenosine amine congener mitigates noise-induced cochlear injury. Purinergic Signal. 2010 Jun;6(2):273-81. DOI:10.1007/s11302-010-9188-5

ADENOSINE AMINE CONGENER (ADAC) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 57)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
NewCan Biotech Limited
+86-571-86912261 19975279805 sales@newcanbio.com China 9985 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39040 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 43333 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501 product@acmec-e.com China 33324 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580 cooperation@kean-chem.com China 40066 58
DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739 info@dycnchem.com China 53802 58

View Lastest Price from ADENOSINE AMINE CONGENER (ADAC) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Adenosine amine congener pictures 2026-04-21 Adenosine amine congener
96760-69-9
US $67.00-247.00 / mg 98.29% 10g TargetMol Chemicals Inc.

ADENOSINE AMINE CONGENER (ADAC) Spectrum

N6-[4-[[[4-[[[(2-AMinoethyl)aMino]carbonyl]Methyl]-anilino]carbonyl]Methyl]phenyl]adenosine hydrate ADENOSINE AMINE CONGENER (ADAC) ADAC, N6-[4-[[[4-[[[(2-Aminoethyl)amino]carbonyl]methyl]-anilino]carbonyl]methyl]phenyl]adenosine hydrate Adenosine amine congener hydrate N-[4-[2-[[4-[2-[(2-Aminoethyl)amino]-2-oxoethyl]phenyl]amino]-2-oxoethyl]phenyl]adenosine Adenosine, N-[4-[2-[[4-[2-[(2-aminoethyl)amino]-2-oxoethyl]phenyl]amino]-2-oxoethyl]phenyl]- N-(2-Aminoethyl)-2-(4-(2-(4-((9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)amino)phenyl)acetamido)phenyl)acetamide P1 receptor,otoprotective,Adenosine amine congener,Adenosine Receptor,loss,hearing,Inhibitor,apoptotic,injury,systemic,A1-adenosine,Cochlear,inhibit,Ca2+,neuroprotective N-(2-aminoethyl)-2-(4-{2-[4-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-6-yl}amino)phenyl]acetamido}phenyl)acetamide Adenosine amine congener, 10 mM in DMSO 96760-69-9 C28H32N8O6 API