5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98
- CAS No.
- 60779-49-9
- Chemical Name:
- 5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98
- Synonyms
- 5-Nitro-6-carboxyuracil;5-Nitroorotic acid, potassium salt mo;6-Carboxy-2-hydroxy-5-nitropyrimidin-4-olate;5-Nitroorotic acid monohydrate potassium salt;5-NITROOROTIC ACID POTASSIUM SALT MONOHYDRATE 98%;5-nitro-2,6-dioxo-3H-pyrimidine-4-carboxylic acid;5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98;2,6-diketo-5-nitro-3H-pyrimidine-4-carboxylic acid;5-nitro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid;5-nitro-2,6-dioxo-1,2,3,4-tetrahydropyrimidine-4-carboxylic acid
- CBNumber:
- CB3501795
- Molecular Formula:
- C5H2KN3O6·H2O
- Molecular Weight:
- 257.2
- MDL Number:
- MFCD00149396
- MOL File:
- 60779-49-9.mol
| Product description | Number | Pack Size | Price |
| 5-Nitro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylicacid 95% | AS145879 | 1g | $121 |
| 5-NITROOROTIC ACID POTASSIUM SALT MONOHYDRATE 95.00% | ING0002114 | 0.5G | $605 |
5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS145879 | 5-Nitro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylicacid 95% | 60779-49-9 | 1g | $121 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ING0002114 | 5-NITROOROTIC ACID POTASSIUM SALT MONOHYDRATE 95.00% | 60779-49-9 | 0.5G | $605 | 2021-12-16 | Buy |
5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98 Chemical Properties,Uses,Production
Application
In Japan, potassium 5-nitroorotate monohydrate is mainly used as an ingredient in over-the-counter multivitamin medications and as an additive in soft drinks. In Western Europe, it is not only a component of pharmaceutical vitamins but also widely used in cosmetics as a nutritional cosmetic matrix, which can be absorbed by skin cells, promoting cell metabolism and inhibiting skin aging. In the United States, there is considerable research on potassium 5-nitroorotate monohydrate. A series of orotic acid-based drugs, such as nitroorotate and aminoorotate, have been developed both domestically and internationally. Potassium 5-nitroorotate monohydrate possesses an asymmetric spatial structure and various coordination functional groups, enabling it to form a rich variety of coordination compounds with different metal ions. Potassium 5-nitroorotate monohydrate is a key intermediate in the synthesis of dipyridamole, which is a precursor in the synthesis of persantin and aggrenox.
Chemical Properties
white to yellow powder
Synthesis
Maintaining cooling to below 50??C, 420 ml (7.68 mol) of concentrated sulfuric acid (H2SO4, about 98%) was added to 169 ml (2.56 mol) of 65% nitric acid (HNO3). Then 200 g of whey acid (1.28 mol; 99.64% purity) was added in batches. The reaction mixture was heated to 50-55??C with stirring and kept for 3 hours. Upon completion of the nitration reaction, the reaction mixture was cooled to ambient temperature (about 10-15??C) and then kept cooled to below 30??C and decanted into 800 ml of water. When the resulting mixture was cooled to about 0-10??C, it was slowly stirred. The precipitated product was filtered and washed with a small amount of cold water and then dried at about 50-60??C to obtain 5-nitro orotate. Weigh KOH, 5-nitro orotate (0.402 g, 2.0 mmol), 1,10-o-phenanthroline (0.360 g, 2.0 mmol) in a round-bottomed flask, add 20 mL of distilled water and 1.0 mL of DMF, and stir for 10 min at room temperature to form a suspension of the mixture, and then transfer it to a stainless steel reactor and react it for 24 h at 100oC, and then naturally cool it to room temperature. Filtered and separated to obtain the bulk crystal 5-nitro orotate potassium salt monohydrate.
5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98 Preparation Products And Raw materials
Raw materials
Preparation Products
5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3987 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35896 | 56 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42934 | 64 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14435 | 57 |
View Lastest Price from 5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-26 | 5-Nitroorotic acid, potassium salt monohydrate
60779-49-9
|
US $0.00-0.00 / ASSAYS | 1ASSAYS | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-12-25 | 5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98
60779-49-9
|
US $1.00 / KG | 1KG | 98%HPLC | 10t | Career Henan Chemical Co |
-
- 5-Nitroorotic acid, potassium salt monohydrate
60779-49-9
- US $0.00-0.00 / ASSAYS
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98
60779-49-9
- US $1.00 / KG
- 98%HPLC
- Career Henan Chemical Co
