LEUKOTRIENE D4 METHYL ESTER
- CAS No.
- 103476-23-9
- Chemical Name:
- LEUKOTRIENE D4 METHYL ESTER
- Synonyms
- Reaxys ID: 5181548;LEUKOTRIENE D4 METHYL ESTER;Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-hydroxy-5-methoxy-5-oxopentyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl- (9CI)
- CBNumber:
- CB3503759
- Molecular Formula:
- C26H42N2O6S
- Molecular Weight:
- 510.69
- MDL Number:
- MOL File:
- 103476-23-9.mol
LEUKOTRIENE D4 METHYL ESTER price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10007165 | Leukotriene D4 methyl ester ≥97% | 103476-23-9 | 25μg | $144 | 2024-03-01 | Buy |
| Cayman Chemical | 10007165 | Leukotriene D4 methyl ester ≥97% | 103476-23-9 | 50μg | $274 | 2024-03-01 | Buy |
| Cayman Chemical | 10007165 | Leukotriene D4 methyl ester ≥97% | 103476-23-9 | 100μg | $519 | 2024-03-01 | Buy |
LEUKOTRIENE D4 METHYL ESTER Chemical Properties,Uses,Production
Description
Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase.1,2 LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.3,4 LTD4 is several hundred fold more potent than LTC4 at the cysteinyl-leukotriene 1 (CysLT1) receptor, but they exhibit approximately equal affinity at the CysLT2 receptor.5,6 LTD4 methyl ester is a more lipid soluble form of LTD4. The biological activity of LTD4 methyl ester has not been reported.WARNING This product is not for human or veterinary use.
References
[1] L ORNING B S S Hammarström. Leukotriene D: a slow reacting substance from rat basophilic leukemia cells.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1980, 77 4: 2014-2017. DOI: 10.1073/pnas.77.4.2014
[2] S HAMMARSTRÖM K B L Orning. Metabolism of leukotrienes.[J]. Molecular and Cellular Biochemistry, 1985, 69 1: 7-16. DOI: 10.1007/bf00225922
[3] PER HEDQVIST. Biological profile of Ieukotrienes C4 and D4[J]. Acta Physiologica, 1980, 110 3: 331-333. DOI: 10.1111/j.1748-1716.1980.tb06676.x
[4] BENGT SAMUELSSON. Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects[J]. Science, 1987, 237 4819. DOI: 10.1126/science.2820055
[5] KEVIN R. LYNCH. Characterization of the human cysteinyl leukotriene CysLT1 receptor[J]. Nature, 1999, 399 6738: 789-793. DOI: 10.1038/21658
[6] C E HEISE. Characterization of the human cysteinyl leukotriene 2 receptor.[J]. The Journal of Biological Chemistry, 2000, 275 39: 30531-30536. DOI: 10.1074/jbc.m003490200
LEUKOTRIENE D4 METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
LEUKOTRIENE D4 METHYL ESTER Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| Cayman Chemical Company | 800-364-9897 | sales@caymanchem.com | China | 6838 | 58 |
| Santa Cruz Biotechnology Inc | 021-60936350 | scbt@scbt.com | China | 6594 | 58 |
| Guangzhou Biopark Technology Co., Ltd. | 020-83808789 | CHINA | 179 | 58 |
