1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
- CAS No.
- 2158302-00-0
- Chemical Name:
- 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
- Synonyms
- (S)-1-Cbz-4-Boc-2-(cyanomethyl)piperazine;(S)-2-(4-Boc-1-Cbz-2-piperazinyl)acetonitrile;O1-benzyl O4-tert-butyl (2S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate;2-Cyanomethyl-piperazine-1,4-dicarboxylic acid 1-benzyl ester 4-tert-butyl ester;1,4-Piperazinedicarboxylic acid, 2-(cyanomethyl)-, 4-(1,1-dimethylethyl) 1-(phenylmethyl) ester, (2S)-
- CBNumber:
- CB35441874
- Molecular Formula:
- C19H25N3O4
- Molecular Weight:
- 359.42
- MDL Number:
- MOL File:
- 2158302-00-0.mol
- MSDS File:
- SDS
| Boiling point | 510.245±35.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 1.178±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | Storage temp. 2-8°C |
| pka | -1.039±0.70(predicted) |
| Appearance | Colorless to light yellow Oil |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 295993 | 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate | 2158302-00-0 | 100.00mg | $80 | 2026-05-19 | Buy |
| Matrix Scientific | 295993 | 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate | 2158302-00-0 | 250.00mg | $150 | 2026-05-19 | Buy |
| Matrix Scientific | 295993 | 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate | 2158302-00-0 | 1.00g | $402 | 2026-05-19 | Buy |
| Synthonix | B62799 | 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate >98% | 2158302-00-0 | 100mg | $150 | 2026-05-06 | Buy |
| Synthonix | B62799 | 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate >98% | 2158302-00-0 | 250mg | $250 | 2026-05-06 | Buy |
1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate Chemical Properties,Uses,Production
Chemical Properties
White solid
Synthesis
Dissolve (S)-3-(cyanomethyl)piperazine-1-carboxylic acid tert-butyl ester (2.25g, 10mmol) in 15mL dichloromethane, add N,N-diisopropylethylamine at room temperature (3.87g, 30mmol) was cooled to 0°C, benzyl chloroformate was added dropwise, and reacted at low temperature for 2h. Add 25 mL of water to the reaction solution, extract the aqueous phase with dichloromethane (30 mL×3), combine the organic phases, wash the organic phase with water (20 mL×2), dry with anhydrous sodium sulfate, concentrate, and separate and purify the crude product by silica gel column chromatography (Ethyl acetate/petroleum ether (v/v)=1:20-1:5) to obtain 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate (3.1 g, yield: 86%).
1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ForeChem (Nantong) Technology Co.,Ltd. | 513-85982855 18921614129 | sales@xianxingpharm.com | China | 2712 | 61 |
| DebyeTec.com Inc. | 18086626237 18086626237 | 2693528373@qq.com | China | 2937 | 56 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4975 | 55 |
| Chengdu DingDang Pharmaceutical Co., Ltd. | 028-86040038 | market@dingdangchem.com | China | 1853 | 55 |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 028-83379370 13880556291 | tcy@tcypharm.com | China | 8696 | 58 |
| Jinan Kabotang Biological Technology Co.,Ltd. | 0531-61320525 15866703830 | figo.gao@foxmail.com | China | 7601 | 58 |
| Shanghai Gugang New Materials Technology Co. Ltd. | 021-51317962 | 296935822@qq.com | China | 995 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49299 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
