OAS2 antibody
- CAS No.
- Chemical Name:
- OAS2 antibody
- Synonyms
- OAS2 antibody
- CBNumber:
- CB35668165
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
OAS2 antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb622740 | OAS2 Antibody | 50μl | $260 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb622740 | OAS2 Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb252203 | OAS2 Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb158043 | OAS2 antibody Affinity purified by Protein A | 100μg | $421.6 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb158043 | OAS2 antibody Affinity purified by Protein A | 200μg | $673.2 | 2021-12-16 | Buy |
OAS2 antibody Chemical Properties, Uses, Production
Source
Rabbit
Reactivity
Human
Background
2’-5’-oligoadenylate synthetase 2 is an enzyme induced by type 1 interferon that plays a key role in the host antiviral innate immune response. The OAS family of proteins includes OAS1, OAS2, OAS3, and OASL in humans. OAS2 is activated by cytosolic dsRNA and its enzymatic activity generates the second messenger 2’-5’-linked oligoadenylate. These 2’-5’-linked oligoadenylates bind to the ribonuclease RNase L, which then degrades viral and cellular RNA in an effort to curb viral replication. Research studies have shown that components of the OAS-RNase L system, including OAS2, are highly upregulated in response to SARS-CoV-2 infection, suggesting a role for this antiviral pathway in the pathogenesis of SARS-CoV-2.
References
[1] Sarkar, S.N. et al. (1999) J Biol Chem 274, 25535-42.
[2] Sarkar, S.N. et al. (1999) J Biol Chem 274, 1848-55.
[3] Choi, U.Y. et al. (2015) Exp Mol Med 47, e144.
[4] Li, Y. et al. (2020) bioRxiv, 2020.09.24.312553. doi: 10.1101/2020.09.24.312553.
[5] Schmidt, N. et al. (2020) Nat Microbiol, doi: 10.1038/s41564-020-00846-z.
OAS2 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
OAS2 antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
