TRADD Antibody
- CAS No.
- Chemical Name:
- TRADD Antibody
- Synonyms
- TRADD Antibody;Mouse Monoclonal TRADD Antibody
- CBNumber:
- CB35701905
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
TRADD Antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb193431 | TRADD Antibody | 50μl | $260 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb256026 | TRADD Antibody | 100μl | $720 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb193431 | TRADD Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb11504 | TRADD antibody Affinity purified by Protein A | 100μg | $402.9 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb11504 | TRADD antibody Affinity purified by Protein A | 200μg | $654.5 | 2021-12-16 | Buy |
TRADD Antibody Chemical Properties,Uses,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Background
Apoptosis mediated by death factors like FasL and TNF-α involves the formation of a death-inducing signaling complex to their respective receptors. Upon ligand activation to their receptors, Fas and TNF-R1 associate with death domain containing adaptor proteins FADD and TRADD. In addition to its carboxy-terminal DD, FADD contains an amino-terminal death effector domain that binds to DEDs found on caspase-8 which leads to activation of this initiator caspase. Caspase-8 subsequently activates downstream effector caspases, like caspase-3, resulting in the cleavage of proteins involved in the execution of apoptosis. Unlike FADD, TRADD does not contain a DED. Apoptosis driven by TNF-R1 binding to TRADD involves association of TRADD and FADD which then leads to activation of caspase-8.
References
[1] Nagata, S. (1997) Cell 88, 355-65.
[2] Chinnaiyan, A.M. et al. (1995) Cell 81, 505-12.
[3] Boldin, M.P. et al. (1995) J. Biol. Chem. 270, 7795-8.
[4] Hsu, H. et al. (1995) Cell 81, 495-504.
[5] Muzio, M. et al. (1996) Cell 85, 817-27.
[6] Boldin, M.P. et al. (1996) Cell 85, 803-15.
[7] Hsu, H. et al. (1996) Cell 84, 299-308.
TRADD Antibody Preparation Products And Raw materials
Raw materials
Preparation Products
TRADD Antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Universal Biotech Co.,Ltd | 58 |
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
