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MK-3281
- CAS No.
- 886041-60-7
- Chemical Name:
- MK-3281
- Synonyms
- 6H-Indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid, 14-cyclohexyl-7-[[2-(dimethylamino)ethyl]methylamino]-7,8-dihydro-, (7R)-
- CBNumber:
- CB35867555
- Molecular Formula:
- C29H37N3O3
- Molecular Weight:
- 475.62
- MDL Number:
- MOL File:
- 886041-60-7.mol
Last updated:2025-04-18 09:52:09
FDA UNII | 3593C180JO |
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MK-3281 Chemical Properties,Uses,Production
Uses
MK3281 (Compound 33) is a non-nucleoside hepatitis C virus (HCV) NS5B polymerase inhibitor, with an EC50 of 28 nM for gt1a[1].
References
[1] Narjes F, et al. Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase. J Med Chem. 2011 Jan 13;54(1):289-301. DOI:10.1021/jm1013105
MK-3281 Preparation Products And Raw materials
Raw materials
Preparation Products
MK-3281 Suppliers
Global( 4)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19905 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19965 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12000 | 58 |
Supplier | Advantage |
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TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 58 |
886041-60-7(MK-3281)Related Search:
MK-3281
methyl 14-cyclohexyl-7-((2-(dimethylamino)ethyl)amino)-7,8-dihydro-6H-benzo[2,3][1,5]oxazocino[5,4-a]indole-11-carboxylate
Methyl (7R)-7-aMino-14-cyclohexyl-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate hydrochloride
methyl 14-cyclohexyl-7-((2-(dimethylamino)ethyl)(methyl)amino)-7,8-dihydro-6H-benzo[2,3][1,5]oxazocino[5,4-a]indole-11-carboxylate
(R)-Methyl 7-((2-aMinoethyl)aMino)-14-cyclohexyl-7,8-dihydro-6H-benzo[2,3][1,5]oxazocino[5,4-a]indole-11-carboxylate
6H-Indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid, 14-cyclohexyl-7-[[2-(dimethylamino)ethyl]methylamino]-7,8-dihydro-, (7R)-
886041-60-7