2-(Trimethylsilyl)ethanol
- CAS No.
- 2916-68-9
- Chemical Name:
- 2-(Trimethylsilyl)ethanol
- Synonyms
- 2-(triMethylsilyl)ethan-1-ol;trimethylsilylethanol;Ethanol, 2-(trimethylsilyl)-;DK254;DK717;DKSI033;0.825 g/ML;DKFELEX0184;2-(TrimethyL;TIMTEC-BB SBB009030
- CBNumber:
- CB3668443
- Molecular Formula:
- C5H14OSi
- Molecular Weight:
- 118.25
- MDL Number:
- MFCD00002825
- MOL File:
- 2916-68-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-(Trimethylsilyl)ethanol 98% | 226890 | 1g | $41.3 |
| 2-(Trimethylsilyl)ethanol 98% | 226890 | 10g | $227 |
| 2-(Trimethylsilyl)ethanol >96.0%(GC) | T1441 | 5mL | $61 |
| 2-(Trimethylsilyl)ethanol >96.0%(GC) | T1441 | 25mL | $198 |
| 2-(Trimethylsilyl)ethanol 98% | 226890 | 50g | $908 |
| More product size | |||
| Boiling point | 71-73 °C35 mm Hg(lit.) |
|---|---|
| Density | 0.825 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 123 °F |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Liquid |
| pka | 15.38±0.10(Predicted) |
| color | Clear colorless |
| Specific Gravity | 0.825 |
| Water Solubility | soluble |
| Hydrolytic Sensitivity | 4: no reaction with water under neutral conditions |
| BRN | 1732034 |
| Stability | Hygroscopic |
| InChI | 1S/C5H14OSi/c1-7(2,3)5-4-6/h6H,4-5H2,1-3H3 |
| InChIKey | ZNGINKJHQQQORD-UHFFFAOYSA-N |
| SMILES | C[Si](C)(C)CCO |
| CAS DataBase Reference | 2916-68-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | GF24TDM0VO |
| NIST Chemistry Reference | Trimethyl-2-hydroxyethylsilane(2916-68-9) |
| UNSPSC Code | 12352000 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226 | |||||||||
| Precautionary statements | P210 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,F | |||||||||
| Risk Statements | 10-36/37/38 | |||||||||
| Safety Statements | 16-37/39-26-24/25 | |||||||||
| RIDADR | UN 1987 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | KM5480000 | |||||||||
| Hazard Note | Flammable | |||||||||
| TSCA | No | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29310095 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Flam. Liq. 3 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,1122mg/kg (1122mg/kg),Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. Vol. 229, Pg. 1011, 1976. | |||||||||
| NFPA 704 |
|
2-(Trimethylsilyl)ethanol price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 226890 | 2-(Trimethylsilyl)ethanol 98% | 2916-68-9 | 1g | $41.3 | 2026-03-19 | Buy |
| Sigma-Aldrich | 226890 | 2-(Trimethylsilyl)ethanol 98% | 2916-68-9 | 10g | $227 | 2026-03-19 | Buy |
| TCI Chemical | T1441 | 2-(Trimethylsilyl)ethanol >96.0%(GC) | 2916-68-9 | 5mL | $61 | 2026-03-19 | Buy |
| TCI Chemical | T1441 | 2-(Trimethylsilyl)ethanol >96.0%(GC) | 2916-68-9 | 25mL | $198 | 2026-03-19 | Buy |
| Sigma-Aldrich | 226890 | 2-(Trimethylsilyl)ethanol 98% | 2916-68-9 | 50g | $908 | 2026-03-19 | Buy |
2-(Trimethylsilyl)ethanol Chemical Properties,Uses,Production
Chemical Properties
CLEAR COLOURLESS LIQUID
Physical properties
bp 50–52 °C/10 mmHg, 71–73 °C/35 mmHg; d 0.825 g cm3.
Uses
2-(Trimethylsilyl)ethanol is used as a protecting reagent for carboxyl, phosphoryl, hydroxyl and amino group in organic synthesis. It is used as a precursor to prepare trimethyl(2-phenoxyethyl)silanes by reacting with aromatic fluoride. It is also used in the synthesis of teoc-protected amines by using the corresponding isocyanates.
Uses
Used to synthesize Teoc-protected amines via alcoholysis of the corresponding isocyanates.
Uses
2-(Trimethylsilyl)ethanol is a protecting reagent for carboxyl, phosphoryl, hydroxyl, and amino groups. It participates in the reactions of Phenol and Acid Protection, Alcohol Protection, Hemiacetal Protection, Amine Protection, Enol Ether Synthesis, Carbohydrate Chemistry etc.
Preparation
Three methods of preparation have been reported: (a) from the treatment of ethyl bromoacetate with zinc followed by the reaction with chlorotrimethylsilane1 and subsequent reduction of the resultant ethyl trimethylsilylacetate with lithium aluminum hydride2,3 or borane¨Ctetrahydrofuran(eq 1); (b) from the hydroboration/oxidation or oxymercuration/demercuration of vinyltrimethylsilane (eq 2); and (c)most conveniently, by the reaction of the Grignard reagent formed from (chloromethyl)trimethylsilane with paraformaldehyde (eq 3).
Purification Methods
If the NMR spectrum is not clean, then dissolve the alcohol in Et2O, wash it with aqueous NH4Cl solution, dry (Na2SO4), evaporate and distil it. The 3,4-dinitrobenzoyl derivative has m 66o (from EtOH). [NMR: Speier et al. J Am Chem Soc 79 974 1957, Z Naturforsch 14b 137 1959, Beilstein 4 IV 3951.]
2-(Trimethylsilyl)ethanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13815 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21592 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
View Lastest Price from 2-(Trimethylsilyl)ethanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-17 | 2-(Trimethylsilyl)ethanol
2916-68-9
|
US $2.20-8.80 / kg | 1kg | 99%min | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2025-06-27 | 2-(Trimethylsilyl)ethanol
2916-68-9
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-06-20 | 2-(Trimethylsilyl)ethanol
2916-68-9
|
US $40.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- 2-(Trimethylsilyl)ethanol
2916-68-9
- US $2.20-8.80 / kg
- 99%min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2-(Trimethylsilyl)ethanol
2916-68-9
- US $0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-(Trimethylsilyl)ethanol
2916-68-9
- US $40.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
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