(6-Bromo-1H-indol-2-yl)methanol
- CAS No.
- 923197-75-5
- Chemical Name:
- (6-Bromo-1H-indol-2-yl)methanol
- Synonyms
- 6-bromo-1H-Indole-2-methanol;1H-Indole-2-methanol, 6-bromo-;(6-Bromo-1H-indol-2-yl)methanol;6-Bromo-2-(hydroxymethyl)-1H-indole;(6-Bromo-1H-indol-2-yl)methanol , 6-Bromo-2-(hydroxymethyl)-1H-indole
- CBNumber:
- CB3699166
- Molecular Formula:
- C9H8BrNO
- Molecular Weight:
- 226.07
- MDL Number:
- MFCD08445239
- MOL File:
- Mol file
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H302-H319 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| Safety Statements | 24/25 |
| HazardClass | IRRITANT |
| HS Code | 29339900 |
(6-Bromo-1H-indol-2-yl)methanol price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 046983 | (6-Bromo-1H-indol-2-yl)methanol | 923197-75-5 | 250.00mg | $69 | 2026-05-18 | Buy |
| Matrix Scientific | 046983 | (6-Bromo-1H-indol-2-yl)methanol | 923197-75-5 | 1.00g | $172 | 2026-05-18 | Buy |
| Matrix Scientific | 046983 | (6-Bromo-1H-indol-2-yl)methanol | 923197-75-5 | 5.00g | $700 | 2026-05-18 | Buy |
| Synthonix | B51508 | (6-Bromo-1H-indol-2-yl)methanol 95+% | 923197-75-5 | 100mg | $180 | 2026-05-06 | Buy |
| Synthonix | B51508 | (6-Bromo-1H-indol-2-yl)methanol 95+% | 923197-75-5 | 250mg | $260 | 2026-05-06 | Buy |
(6-Bromo-1H-indol-2-yl)methanol Chemical Properties,Uses,Production
Chemical Properties
White to light yellow powder or solid
Synthesis
16732-65-3
923197-75-5
General procedure for the synthesis of (6-bromo-1H-indol-2-yl)methanol from 6-bromoindole-2-carboxylic acid: to a solution of 6-bromo-1H-indole-2-carboxylic acid (1.00 g, 4.20 mmol) in tetrahydrofuran (THF, 20.0 mL) was added slowly and dropwise at 0 °C lithium aluminium hydroxide (LiAlH4, 1.0 M solution in THF, 4.20 mL. 4.20 mmol). The reaction mixture was gradually warmed to room temperature with stirring for 4 hours. Upon completion of the reaction, the reaction was quenched by sequential addition of water and 15% aqueous sodium hydroxide (NaOH) solution at 0°C, at which time a precipitate was generated. The reaction mixture was filtered through a diatomaceous earth pad and the filtrate was extracted with ethyl acetate (EtOAc, 3 x 20 mL). The organic phases were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to afford the target product (6-bromo-1H-indol-2-yl)methanol (696 mg, 73% yield) as a yellow solid. The product was characterized by 1H NMR (500 MHz, CDCl3): δ 7.51 (s, 1H), 7.43 (d, J=8.0 Hz, 1H), 7.20 (dd, J=8.0,1.6 Hz, 1H), 6.38 (s, 1H), 4.83 (d, J=5.6 Hz, 2H).
References
[1] Liebigs Annalen der Chemie, 1986, # 3, p. 438 - 455
[2] Patent: US2012/157469, 2012, A1. Location in patent: Page/Page column 28-29
[3] Journal of Medicinal Chemistry, 2014, vol. 57, # 2, p. 364 - 377
(6-Bromo-1H-indol-2-yl)methanol Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
(6-Bromo-1H-indol-2-yl)methanol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3992 | 55 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| AOKBIO Inc. | 021-68712331 3286104197 | China | 321 | 55 | |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9996 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Anmike Chemical Co. Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 9988 | 55 |
| Dezhou LonWel Pharmaceutical Technology Co., Ltd. | 13761310616 | 39324283@qq.com | China | 1360 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28763 | 58 |
