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4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE structure

CAS No.: 175137-21-0

Chemical Name:: 4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE

Synonyms: BUTTPARK 46\18-89;4-Chloro-7-Methylthieno[3...;7-CHLORO-3-METHYLTHIENO(3,2-D)PYRIMIDINE;4-Chloro-7-methylthieno[2,3-d]pyrimidine;4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE;Thieno[3,2-d]pyrimidine,4-chloro-7-methyl-;4-Chloro-7-methylthieno[3,2-d]pyrimidine97%;4-Chloro-7-methylthieno[3,2-d]pyrimidine 97%;4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE ISO 9001：2015 REACH

CBNumber:: CB3701869

Molecular Formula:: C7H5ClN2S

Molecular Weight:: 184.65

MDL Number:: MFCD00205202

MOL File:: 175137-21-0.mol

Last updated:2025-07-24 18:13:49

Product description	Number	Pack Size	Price
4-Chloro-7-methylthieno[3,2-d]pyrimidine	C368488	100mg	$60
4-Chloro-7-methylthieno[3,2-d]pyrimidine 97%	084152	5g	$104
4-Chloro-7-methylthieno[3,2-d]pyrimidine 97%	084152	1g	$27
4-Chloro-7-methylthieno[3,2-d]pyrimidine 97%	7H66-5-X6	250mg	$49
4-Chloro-7-methylthieno[3,2-d]pyrimidine 97%	7H66-5-X6	1g	$160
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4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE Properties

Melting point	124 °C
Boiling point	301.3±37.0 °C(Predicted)
Density	1.445±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	0.78±0.40(Predicted)
Appearance	Off-white to light yellow Solid
InChI	InChI=1S/C7H5ClN2S/c1-4-2-11-6-5(4)9-3-10-7(6)8/h2-3H,1H3
InChIKey	IYJDOVYAFDVIDB-UHFFFAOYSA-N
SMILES	C1=NC(Cl)=C2SC=C(C)C2=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P280-P301+P312-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36
Safety Statements	26
Hazard Note	Irritant
HS Code	2934999090

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	C368488	4-Chloro-7-methylthieno[3,2-d]pyrimidine	175137-21-0	100mg	$60	2021-12-16	Buy
Matrix Scientific	084152	4-Chloro-7-methylthieno[3,2-d]pyrimidine 97%	175137-21-0	5g	$104	2021-12-16	Buy
Matrix Scientific	084152	4-Chloro-7-methylthieno[3,2-d]pyrimidine 97%	175137-21-0	1g	$27	2021-12-16	Buy
SynQuest Laboratories	7H66-5-X6	4-Chloro-7-methylthieno[3,2-d]pyrimidine 97%	175137-21-0	250mg	$49	2021-12-16	Buy
SynQuest Laboratories	7H66-5-X6	4-Chloro-7-methylthieno[3,2-d]pyrimidine 97%	175137-21-0	1g	$160	2021-12-16	Buy

Product number	Packaging	Price	Buy
C368488	100mg	$60	Buy
084152	5g	$104	Buy
084152	1g	$27	Buy
7H66-5-X6	250mg	$49	Buy
7H66-5-X6	1g	$160	Buy

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE Chemical Properties,Uses,Production

Synthesis

7-METHYL-3,4-DIHYDROTHIENO[3,2-D]PYRIMIDIN-4-ONE

175137-13-0

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE

175137-21-0

General procedure for the synthesis of 4-chloro-7-methylthieno[3,2-d]pyrimidin-4(1H)-one from 7-methylthieno[3,2-d]pyrimidin-4-one: 7-methyl-3H-thieno[3,2-d]pyrimidin-4-one (167, 10.6 g, 64.0 mmol) was dissolved in phosphorus nitrogen oxide (42 mL), and the reaction was carried out for 2 h under nitrogen protection at reflux. Upon completion of the reaction, the reaction solution was cooled to room temperature and slowly poured into saturated aqueous sodium carbonate solution (300 mL) for neutralization. Subsequently, the aqueous phase was extracted with ethyl acetate, and the organic layers were combined, washed with water and saturated brine sequentially, and then dried with anhydrous magnesium sulfate. The organic solvent was removed by concentration under reduced pressure and the resulting residue was dried under vacuum overnight in the presence of phosphorus pentoxide to afford the white solid product 4-chloro-7-methylthieno[3,2-d]pyrimidine (168, 11.2 g, 95% yield).

References

[1] Patent: US2006/4002, 2006, A1. Location in patent: Page/Page column 12; 21; 23; 30; 31-32
[2] Patent: WO2013/100632, 2013, A1. Location in patent: Page/Page column 62
[3] Patent: US2014/371219, 2014, A1. Location in patent: Paragraph 0436; 0437
[4] Patent: WO2012/156756, 2012, A2. Location in patent: Page/Page column 99
[5] Patent: WO2011/93684, 2011, A2. Location in patent: Page/Page column 33; 34

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE synthesis

Synthesis of 4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE from 7-METHYL-3,4-DIHYDROTHIENO[3,2-D]PYRIMIDIN-4-ONE

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE Preparation Products And Raw materials

Raw materials

Sodium hydride Acetonitrile Acetic anhydride Ammonium formate Methyl 3-mercaptopropionate

Formic acid Phosphorus oxitrichloride Hydroxylamine hydrochloride Methyl methacrylate 1,2-Dimethoxyethane

Sodium carbonate Formamide

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Preparation Products

7-METHYL-3,4-DIHYDROTHIENO[3,2-D]PYRIMIDIN-4-ONE Thieno[3,2-d]pyrimidine-7-carboxylic acid, 4-chloro- 7-methylthieno[3,2-d]pyrimidin-4-amine

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE Suppliers

Global( 106)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	7099	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from 4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-06-25	4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE 175137-21-0	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
	2019-07-06	4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE 175137-21-0	US $1.00 / KG	1KG	98%	100KG	Career Henan Chemical Co

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE
175137-21-0
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE
175137-21-0
US $1.00 / KG
98%
Career Henan Chemical Co

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE Spectrum

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE(175137-21-0)¹HNMR

175137-21-0(4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE)Related Search:

Dichloromethane 4-CHLORO-6-METHYLTHIENO[2,3-D]PYRIMIDINE 4-Chloro-5-methylthieno[2,3-d]pyrimidine ,97%,4-CHLORO-5-METHYLTHIENO[2,3-D]PYRIMIDINE 2-chloro-5-methylthieno[2,3-d]pyrimidine 4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE

4-CHLORO-2-METHYL-THIENO[2,3-D]PYRIMIDINE 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine 4-CHLORO-7-(4-CHLOROPHENYL)THIENO[3,2-D]PYRIMIDINE 4-CHLORO-7-PHENYL-THIENO[3,2-D]PYRIMIDINE 4-chloro-2-methylthieno[3,2-d]pyrimidine

4-CHLORO-7-(4-METHOXY-PHENYL)-THIENO[3,2-D]-PYRIMIDINE ETHYL 2-([(4-BROMOPHENYL)THIO]METHYL)-4-CHLORO-5-METHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXYLATE METHYL 2-BENZYL-4-CHLORO-5-METHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXYLATE ETHYL 4-CHLORO-5-METHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXYLATE 4-CHLORO-7-(4-ETHOXYPHENYL)THIENO[3,2-D]PYRIMIDINE

4-CHLORO-7-(4-FLUOROPHENYL)-THIENO[3,2-D] PYRIMIDINE 7-(4-BROMOPHENYL)-4-CHLOROTHIENO[3,2-D]PYRIMIDINE 4-CHLORO-7-(4-NITROPHENYL)THIENO[3,2-D]PYRIMIDINE

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4-Chloro-7-methylthieno[3,2-d]pyrimidine 97% 4-Chloro-7-Methylthieno[3... 4-Chloro-7-methylthieno[3,2-d]pyrimidine97% BUTTPARK 46\18-89 4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE 4-Chloro-7-methylthieno[2,3-d]pyrimidine 7-CHLORO-3-METHYLTHIENO(3,2-D)PYRIMIDINE Thieno[3,2-d]pyrimidine,4-chloro-7-methyl- 4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE ISO 9001：2015 REACH 175137-21-0