ChemicalBook >> CAS DataBase List >>2-Amino-3-benzyloxypyridine

2-Amino-3-benzyloxypyridine

2-Amino-3-benzyloxypyridine structure

CAS No.: 24016-03-3

Chemical Name:: 2-Amino-3-benzyloxypyridine

Synonyms: 3-(BENZYLOXY)PYRIDIN-2-AMINE;NSC 298538;TIMTEC-BB SBB000394;2-Amino-3-benzyloxyp;Indacaterol Impurity 76;3-Benzyloxy-2-pyridylamin;3-Benzyloxy-2-pyridylamine;2-AMINO-3-BENZYLOXYPYRIDINE;3-Benzyloxy-2-aminopyridine;4-(Benzyloxy)-2-pyridinamine

CBNumber:: CB3703762

Molecular Formula:: C12H12N2O

Molecular Weight:: 200.24

MDL Number:: MFCD00006316

MOL File:: 24016-03-3.mol

MSDS File:: SDS

Last updated:2026-01-13 11:19:32

Product description	Number	Pack Size	Price
2-Amino-3-benzyloxypyridine 99%	144487	5g	$102
2-Amino-3-benzyloxypyridine 99%	144487	25g	$219
2-Amino-3-benzyloxypyridine >98.0%(T)	A2080	5g	$35
2-Amino-3-benzyloxypyridine >98.0%(T)	A2080	25g	$104
2-Amino-3-benzyloxypyridine	A1375-64	1g	$312
More product size

Request For Quotation

2-Amino-3-benzyloxypyridine Properties

Melting point	92-94 °C (lit.)
Boiling point	337.96°C (rough estimate)
Density	1.1131 (rough estimate)
refractive index	1.6660 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	8.40±0.10(Predicted)
form	Crystalline Powder
color	Green to brown
BRN	392674
InChI	InChI=1S/C12H12N2O/c13-12-11(7-4-8-14-12)15-9-10-5-2-1-3-6-10/h1-8H,9H2,(H2,13,14)
InChIKey	NMCBWICNRJLKKM-UHFFFAOYSA-N
SMILES	C1(N)=NC=CC=C1OCC1=CC=CC=C1
CAS DataBase Reference	24016-03-3(CAS DataBase Reference)
FDA UNII	IYW7T7718Z
NIST Chemistry Reference	2-Pyridinamine, 3-(phenylmethoxy)-(24016-03-3)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-20/21/22

Safety Statements

26-37/39-24/25-36/37/39-22,26-36

RIDADR

UN2811

WGK Germany

Hazard Note

Irritant

HS Code

29221985

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

2-Amino-3-benzyloxypyridine price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	144487	2-Amino-3-benzyloxypyridine 99%	24016-03-3	5g	$102	2025-07-31	Buy
Sigma-Aldrich	144487	2-Amino-3-benzyloxypyridine 99%	24016-03-3	25g	$219	2023-06-20	Buy
TCI Chemical	A2080	2-Amino-3-benzyloxypyridine >98.0%(T)	24016-03-3	5g	$35	2025-07-31	Buy
TCI Chemical	A2080	2-Amino-3-benzyloxypyridine >98.0%(T)	24016-03-3	25g	$104	2025-07-31	Buy
Usbiological	A1375-64	2-Amino-3-benzyloxypyridine	24016-03-3	1g	$312	2021-12-16	Buy

Product number	Packaging	Price	Buy
144487	5g	$102	Buy
144487	25g	$219	Buy
A2080	5g	$35	Buy
A2080	25g	$104	Buy
A1375-64	1g	$312	Buy

2-Amino-3-benzyloxypyridine Chemical Properties,Uses,Production

Chemical Properties

Brown crystalline powder

Uses

2-Amino-3-benzyloxypyridine is used in preparation of pyridinyl/pyridazinyloxymethyl substituted Raf kinase inhibitors.

Uses

2-Amino-3-benzyloxypyridine was used in the synthesis of 1-acetyl-2-[2-(3-benzyloxypyridinyl)]iminoimidazolidine.

General Description

2-Amino-3-benzyloxypyridine on condensation with diethyl ethoxymethylene malonate affords 9-benzyloxy-3-ethoxycarbonylpyrido[1,2-a]pyrimidin-4-one.

Biochem/physiol Actions

2-Amino-3-benzyloxypyridine is an inhibitor of mitogen-activated protein kinase p38α activity.

Synthesis

16867-03-1

100-44-7

24016-03-3

At a temperature lower than 40°C, 48L of deionized water was added to a 300L stainless steel reactor, and 48kg of sodium hydroxide was added under slow stirring until completely dissolved. Subsequently, 16 kg of 2-amino-3-hydroxypyridine, 1.6 kg of tetrabutylammonium bromide, and 17.92 L of benzyl chloride were added sequentially to the sodium hydroxide solution. The reaction mixture was heated to 70~75°C and kept at this temperature for 6 hours. When the reaction was completed, stirring was stopped and the mixture was left to stratify. The aqueous phase was extracted with toluene (20L x 3) and the combined organic phases were washed with pure water (30L x 2). The organic phase was concentrated until a large amount of solid precipitated, followed by crystallization at 0~5°C and stirring for 2 hours. Upon completion of crystallization, centrifugation was performed and the filter cake was washed with 3.2 L of pre-cooled toluene. Finally, it was dried under vacuum at 50~55°C for 3 h to give 22.5 kg of bright yellow solid Intermediate II (2-amino-3-benzyloxypyridine) in 77.3% molar yield and 99.53% purity.

References

[1] Chemistry Letters, 2006, vol. 35, # 3, p. 270 - 271
[2] Synthesis, 1981, # 12, p. 971 - 973
[3] Patent: CN107311998, 2017, A. Location in patent: Paragraph 0035-0036
[4] Journal of Chemical Research, Miniprint, 1986, # 11, p. 3368 - 3390
[5] Patent: CN103570683, 2018, B. Location in patent: Paragraph 0927; 0928; 0930; 0931

2-Amino-3-benzyloxypyridine synthesis

Synthesis of 2-Amino-3-benzyloxypyridine from 2-Amino-3-hydroxypyridine and Benzyl chloride

2-Amino-3-benzyloxypyridine Preparation Products And Raw materials

Raw materials

2-Amino-3-hydroxypyridine TETRABUTYLAMMOMIUM BROMIDE Sodium hydroxide Benzyl chloride Benzyl bromide

Preparation Products

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 8-(benzyloxy)-2-methylimidazo[1,2-a]pyridine 8-BENZYLOXY-2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER [1,2,4]Triazolo[1,5-a]pyridin-2-amine, 8-(phenylmethoxy)-

2-Amino-3-benzyloxypyridine Suppliers

Global( 409)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8753	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20128	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21599	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29833	58
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	923	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2950	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
QUALITY CONTROL CHEMICALS INC.	+86-66853366 +86-15920483169	orders@qccstandards.com	United States	26	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
NINGBO INNO PHARMCHEM CO., LTD.	58
Jinan Finer Chemical Co., Ltd	58
Accela ChemBio Inc.	58
QUALITY CONTROL CHEMICALS INC.	58
Shandong chuangyingchemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 2-Amino-3-benzyloxypyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-01-05	2-Amino-3-benzyloxypyridine 24016-03-3	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-12-01	2-Amino-3-benzyloxypyridine 24016-03-3	US $0.00-0.00 / KG	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-11-18	2-Amino-3-benzyloxypyridine 24016-03-3	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited

2-Amino-3-benzyloxypyridine
24016-03-3
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-Amino-3-benzyloxypyridine
24016-03-3
US $0.00-0.00 / KG
98.0%
Shaanxi Dideu New Materials Co. Ltd

2-Amino-3-benzyloxypyridine
24016-03-3
US $1.10 / g
99.00%
Dideu Industries Group Limited

2-Amino-3-benzyloxypyridine Spectrum

2-Amino-3-benzyloxypyridine(24016-03-3)MS 2-Amino-3-benzyloxypyridine(24016-03-3)¹HNMR 2-Amino-3-benzyloxypyridine(24016-03-3)¹³CNMR 2-Amino-3-benzyloxypyridine(24016-03-3)IR1 2-Amino-3-benzyloxypyridine(24016-03-3)IR2 2-Amino-3-benzyloxypyridine(24016-03-3)Raman

24016-03-3(2-Amino-3-benzyloxypyridine)Related Search:

4-Dimethylaminopyridine 4-Methoxybenzylchloride 3-Aminopyridine Glycine ALTRENOGEST

2-Aminopyridine 6-Aminocaproic acid Iminodibenzyl 3-Aminophenol Tris(hydroxymethyl)aminomethane

3-AMINO-2-BENZYLOXYPYRIDINE Pyridine 3-Phenoxypyridine 3-[(3,4-DICHLOROBENZYL)OXY]PYRIDIN-2-AMINE 2-Amino-3-benzyloxypyridine

AMINO ACIDS 1-(3-CHLOROPHENYL)-3-(3-(PHENYLMETHOXY)(2-PYRIDYL))UREA 1-(CYCLOHEXYL)-3-(3-(PHENYLMETHOXY)(2-PYRIDYL))UREA

1of4

TIMTEC-BB SBB000394 3-(Benzyloxy)pyridin-2-amine, 2-Aminopyridin-3-yl benzyl ether 2-AMino-3-benzyloxypyridine, 98.5% 5GR 2-Amino-3-benzyloxypyridine ,99% 2-Amino-3-benzyloxyp 2-amino-3-(phenylmethoxy)pyridine 2-Amino-3-benzyloxypyridine, 98.5% NSC 298538 2-Amino-3-benzyloxypyridine 99% 2-AMino-3-benzyloxypyridine, 97+% 3-(BENZYLOXY)PYRIDIN-2-AMINE 3-Benzyloxy-2-pyridylamine 2-AMINO-3-BENZYLOXYPYRIDINE 3-Benzyloxy-2-aminopyridine 3-Benzyloxy-pyridin-2-ylamine 4-(Benzyloxy)-2-pyridinamine Pyridine, 2-amino-3-(benzyloxy)- 2-Amino-3-benzyloxypyridine, 98+% 2-Amino-3-benzyloxypyridine, 98.50% 3-(Phenylmethoxy)pyridin-2-amine 3-(Benzyloxy)pyridine-2-amine 3-(Phenylmethoxy)-2-pyridinamine 2-Pyridinamine, 3-(phenylmethoxy)- 2-Amino-3-benzyloxypyridine > 3-Benzyloxy-2-pyridylamin 2-Amino-3-benzyloxypyridine ISO 9001：2015 REACH Indacaterol Impurity 76 2-Amino-3-benzyloxypyridine, 95% 24016-03-3 C12H12N2O C9 to C46 Building Blocks Heterocyclic Building Blocks Pyridines Amines Aromatics Heterocycles A-AM Bioactive Small Molecules Building Blocks C12 Cell Biology Chemical Synthesis Heterocyclic Building Blocks Pyridines C9 to C46 Heterocyclic Building Blocks Bases & Related Reagents Nucleotides Pyridine Pyridines derivates Nucleotides and Nucleosides Pyridines, Pyrimidines, Purines and Pteredines Heterocyclic Series