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BOC-TRANS-4-AMINOCYCLOHEXANOL

BOC-TRANS-4-AMINOCYCLOHEXANOL structure

CAS No.: 111300-06-2

Chemical Name:: BOC-TRANS-4-AMINOCYCLOHEXANOL

Synonyms: tert-butyl ((1r,4r)-4-hydroxycyclohexyl)carbaMate;104582;tert-butyl (1r;BOC-TRANS-4-AMINOCYCLOHEXANOL;TRANS-4-BOC-AMINOCYCLOHEXANOL;Trans-4-n-boc-aminocylohexanol;TRANS-4-N-BOC-AMINOCYCLOHEXANOL;TRANS-N-4-BOC-AMINOCYCLOHEXANOL;TRANS-N-BOC-4-AMINO-CYCLOHEXANOL;TRANS-4-BOC-AMINO-1-CYCLOHEXANOL

CBNumber:: CB3708479

Molecular Formula:: C11H21NO3

Molecular Weight:: 215.29

MDL Number:: MFCD03844613

MOL File:: 111300-06-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 04:45:37

Product description	Number	Pack Size	Price
trans-4-(tert-Butoxycarbonylamino)cyclohexanol >98.0%(GC)(N)	B3564	1g	$22
trans-4-(tert-Butoxycarbonylamino)cyclohexanol >98.0%(GC)(N)	B3564	5g	$67
trans-4-(Boc-amino)cyclohexanol	467858	10g	$403
trans-4-(Boc-amino)cyclohexanol	467858	25g	$631
4-N-Boc-amino-cyclohexanol ≥96% (HPLC) ≥96%(HPLC)	233410	250mg	$200
More product size

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BOC-TRANS-4-AMINOCYCLOHEXANOL Properties

Melting point	172-173°C
Boiling point	337.7±31.0 °C(Predicted)
Density	1.06±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform. Ethyl Acetate
form	powder to crystal
pka	12.36±0.40(Predicted)
color	White to Almost white
InChIKey	DQARDWKWPIRJEH-KYZUINATSA-N
CAS DataBase Reference	111300-06-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H335-H315-H319

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36/37/39

Hazard Note

Irritant

HS Code

2906190090

NFPA 704

	1
2		0

BOC-TRANS-4-AMINOCYCLOHEXANOL price More Price(79)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B3564	trans-4-(tert-Butoxycarbonylamino)cyclohexanol >98.0%(GC)(N)	111300-06-2	1g	$22	2026-04-30	Buy
TCI Chemical	B3564	trans-4-(tert-Butoxycarbonylamino)cyclohexanol >98.0%(GC)(N)	111300-06-2	5g	$67	2026-04-30	Buy
Usbiological	467858	trans-4-(Boc-amino)cyclohexanol	111300-06-2	10g	$403	2026-06-03	Buy
Usbiological	467858	trans-4-(Boc-amino)cyclohexanol	111300-06-2	25g	$631	2026-06-03	Buy
Usbiological	233410	4-N-Boc-amino-cyclohexanol ≥96% (HPLC) ≥96%(HPLC)	111300-06-2	250mg	$200	2026-06-03	Buy

Product number	Packaging	Price	Buy
B3564	1g	$22	Buy
B3564	5g	$67	Buy
467858	10g	$403	Buy
467858	25g	$631	Buy
233410	250mg	$200	Buy

BOC-TRANS-4-AMINOCYCLOHEXANOL Chemical Properties,Uses,Production

Uses

trans-4-(Boc-amino)cyclohexanol is an intermediate in the synthesis of potent activators of Heme-regulated inhibitor kinase.

Synthesis

24424-99-5

50910-54-8

111300-06-2

Step 1: trans-4-Aminocyclohexanol hydrochloride (5.0 g, 33 mmol) was dissolved in 1,4-dioxane (100 mL) and the resulting solution was cooled to 0 °C. Aqueous sodium hydroxide solution (40 mL, 1 N) was slowly added and the reaction mixture was stirred for 15 minutes. Subsequently, di-tert-butyl dicarbonate (7.9 g, 36 mmol) pre-dissolved in 1,4-dioxane (65 mL) was added. The reaction mixture was stirred at room temperature for 14 hours. Upon completion of the reaction, the reaction mixture was neutralized with 1 N hydrochloric acid and extracted with ethyl acetate. The organic phase was washed sequentially with 1 N hydrochloric acid, water and saturated saline, dried over anhydrous sodium sulfate, filtered and concentrated in vacuum to give the white solid product trans-4-BOC-aminocyclohexanol (7.0 g, 100% yield). Mass spectrometry analysis showed (M + H)+ = 216.15.

References

[1] Patent: US2005/54626, 2005, A1. Location in patent: Page/Page column 47
[2] Heterocycles, 2002, vol. 58, p. 471 - 504
[3] Patent: WO2007/67629, 2007, A1. Location in patent: Page/Page column 63

BOC-TRANS-4-AMINOCYCLOHEXANOL Preparation Products And Raw materials

Raw materials

Carbonic acid, bis(1,1-dimethylethyl) ester Di-tert-butyl dicarbonate trans-4-Aminocyclohexanol trans-4-Aminocyclohexanol hydrochloride Water

Sodium hydroxide 1,4-Dioxane

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Preparation Products

TRANS-4-(BOC-AMINO)CYCLOHEXYL METHANESULFONATE

BOC-TRANS-4-AMINOCYCLOHEXANOL Suppliers

Global( 200)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
BTC Nantong Pharmaceuticals Technology Co.,Ltd	+86-0513-81283365	Info@btcpharm.com	China	251	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
Shenzhen Excellent Biotech Co., Ltd.	13480692018	ramyan@ex-biotech.com	CHINA	954	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10236	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
BTC Nantong Pharmaceuticals Technology Co.,Ltd	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
Shenzhen Excellent Biotech Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hubei Ipure Biology Co., Ltd	58

View Lastest Price from BOC-TRANS-4-AMINOCYCLOHEXANOL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-02-26	BOC-TRANS-4-AMINOCYCLOHEXANOL 111300-06-2		1kg	98%		BTC Nantong Pharmaceuticals Technology Co.,Ltd
2021-07-02	BOC-TRANS-4-AMINOCYCLOHEXANOL 111300-06-2	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2020-01-03	BOC-TRANS-4-AMINOCYCLOHEXANOL 111300-06-2	$1.00	1KG	99%	1000kgs	Career Henan Chemical Co

BOC-TRANS-4-AMINOCYCLOHEXANOL
111300-06-2
98%
BTC Nantong Pharmaceuticals Technology Co.,Ltd

BOC-TRANS-4-AMINOCYCLOHEXANOL
111300-06-2
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

BOC-TRANS-4-AMINOCYCLOHEXANOL
111300-06-2
$1.00
99%
Career Henan Chemical Co

BOC-TRANS-4-AMINOCYCLOHEXANOL Spectrum

BOC-TRANS-4-AMINOCYCLOHEXANOL(111300-06-2)¹HNMR

111300-06-2(BOC-TRANS-4-AMINOCYCLOHEXANOL)Related Search:

Carbamic acid, 3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester, tert-butyl 1H-pyrrol-2-ylcarbamate 2-(BOC-AMINO)-3-METHYLPYRIDINE tert-butyl (3-fluoropropyl)(2-hydroxyethyl)carbamate tert-butyl (3-formyl-4-hydroxyphenyl)carbamate

TRANS-(4-HYDROXY-CYCLOHEXYLMETHYL)-CARBAMIC ACID TERT-BUTYL ESTER CarbaMic acid,[trans-4-[[[(1,1-diMethylethoxy)carbonyl]aMino]Methyl]cyclohexyl]-, phenylMethyl ester Cyclohexanol N-(3-AMino[1,1'-biphenyl]-4-yl)-carbaMic Acid tert-Butyl Ester tert-butyl (2-bromo-3-fluorophenyl)carbamate

tert-Butyl(3-formylbicyclo[1.1.1]pentan-1-yl)carbamate tert-butyl (3-(hydroxymethyl)bicyclo[1.1.1]pentan-1-yl)carbamate tert-butyl (2,2,3,3-tetramethylcyclopropyl)carbamate tert-butyl (3,5-dibromopyrazin-2-yl)carbamate Methyl trans-4-(tert-butoxycarbonylamino)cyclohexanecarboxylate

BOC-1,4-TRANS-ACHC-OH TERT-BUTYL TRANS-4-FORMYLCYCLOHEXYLCARBAMATE 4-Aminocyclohexanol

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BOC-TRANS-4-AMINOCYCLOHEXANOL TERT-BUTYL TRANS-4-HYDROXYCYCLOHEXYLCARBAMATE N-T-BOC-TRANS-4-AMINO CYCLOHEXANOL TRANS-4-N-BOC-AMINOCYCLOHEXANOL TRANS-(4-HYDROXY-CYCLOHEXYL)-CARBAMIC ACID TERT-BUTYL ESTER TRANS-4-BOC-AMINO-1-CYCLOHEXANOL TRANS-4-BOC-AMINOCYCLOHEXANOL TRANS-T-BUTYL-4-HYDROXYCYCLOHEXYLCARBAMATE TRANS-N-BOC-4-AMINO-CYCLOHEXANOL TRANS-N-4-BOC-AMINOCYCLOHEXANOL trans-4-Aminocyclohexanol, N-BOC protected trans-tert-Butyl-4-hydroxycyclohexylcarbamate Boc-trans-4-aminocyclohexanol/CH63857 Boc-trans-4-aminocyclohexanol/CH85402 trans-4-Aminocyclohexanol, N-BOC protected 98% trans-4-(tert-Butoxycarbonylamino)cyclohexanol 104582 tert-Butyl (trans-4-hydroxycyclohex-1-yl)carbamate, trans-4-[(tert-Butoxycarbonyl)amino]cyclohexan-1-ol trans-4-Aminocyclohexan-1-ol, N-BOC protected 98% CarbaMic acid, N-(trans-4-hydroxycyclohexyl)-, 1,1-diMethylethyl ester N-(trans-4-Hydroxy-cyclohexyl)-carbamic acid tert-butyl ester trans-4-Aminocyclohexan-1-ol,N-BOCprotected98% trans-4-(tert-Butoxycarbonylamino)cyclohexanol 4r)-4-hydroxycyclohexylcarbaMate tert-butyl (1r trans-4-(tert-Butoxycarbonylamino)cyclohexanol > tert-butyl(trans-4-hydroxcyclohexyl)carbamate trans-N-4-Boc-aminocyclohexanol, 98% trans-4-Aminocyclohexan-1-ol, N-BOC protected Trans-4-n-boc-aminocylohexanol tert-butyl ((1r,4r)-4-hydroxycyclohexyl)carbaMate 111300-06-2 11300-06-2 pharmacetical API intermediates pharmaceutical