IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE
- CAS No.
- 78162-58-0
- Chemical Name:
- IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE
- Synonyms
- Dexmedetomidine Impurity 27;1-(DIMETHYLSULFAMOYL)IMIDAZOLE;1-(Dimethylsulfamoyl)-1H-imidazole;N,N-dimethylimidazol-1-sulfonamide;1-(Dimethylsulphamoyl)-1H-imidazole;N,N-DIMETHYL IMIDAZOLE-1-SULFONAMIDE;1-(N,N-Dimethylsulfamoyl)-1H-imidazole;N,N-Dimethyl-1H-imidazol-1-sulfonamide;N,N-Dimethyl-1H-imidazole-1-sulfonamide;Imidazole-1-sulfonic acid dimethylamide
- CBNumber:
- CB3720727
- Molecular Formula:
- C5H9N3O2S
- Molecular Weight:
- 175.21
- MDL Number:
- MFCD00955713
- MOL File:
- 78162-58-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-(Dimethylsulfamoyl)imidazole 97% | 524883 | 5g | $68 |
| N,N-Dimethyl-1H-imidazole-1-sulfonamide >98.0%(GC) | D5437 | 1g | $21 |
| N,N-Dimethyl-1H-imidazole-1-sulfonamide >98.0%(GC) | D5437 | 5g | $72 |
| 1-(N,N-Dimethylsulfamoyl)-1H-imidazole | D479315 | 25g | $495 |
| 1-(N,N-Dimethylsulfamoyl)-1H-imidazole | D479315 | 5G | $170 |
| More product size | |||
| Melting point | 48-51 °C (lit.) |
|---|---|
| Boiling point | 83-87 °C(Press: 0.6 Torr) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| Flash point | 230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 2.41±0.10(Predicted) |
| form | Solid |
| color | Pale Yellow |
| InChI | InChI=1S/C5H9N3O2S/c1-7(2)11(9,10)8-4-3-6-5-8/h3-5H,1-2H3 |
| InChIKey | YRRWNBMOJMMXQY-UHFFFAOYSA-N |
| SMILES | C1N(S(N(C)C)(=O)=O)C=CN=1 |
| CAS DataBase Reference | 78162-58-0(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| Hazard Note | Harmful |
| HazardClass | IRRITANT |
| HS Code | 2933299090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 524883 | 1-(Dimethylsulfamoyl)imidazole 97% | 78162-58-0 | 5g | $68 | 2023-06-20 | Buy |
| TCI Chemical | D5437 | N,N-Dimethyl-1H-imidazole-1-sulfonamide >98.0%(GC) | 78162-58-0 | 1g | $21 | 2026-04-30 | Buy |
| TCI Chemical | D5437 | N,N-Dimethyl-1H-imidazole-1-sulfonamide >98.0%(GC) | 78162-58-0 | 5g | $72 | 2026-04-30 | Buy |
| TRC | D479315 | 1-(N,N-Dimethylsulfamoyl)-1H-imidazole | 78162-58-0 | 25g | $495 | 2021-12-16 | Buy |
| TRC | D479315 | 1-(N,N-Dimethylsulfamoyl)-1H-imidazole | 78162-58-0 | 5G | $170 | 2021-12-16 | Buy |
IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE Chemical Properties,Uses,Production
Chemical Properties
IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE is Yellow Semi-Solid
Uses
IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE is an Imidazole (I350200) derivative, used in the preparation of Histamine H3 Receptor Agonists and druglike angiotensin II compounds with affinity for the AT2 r eceptor.
Uses
1-(N,N-Dimethylsulfamoyl)-1H-imidazole is an Imidazole (I350200) derivative, used in the preparation of Histamine H3 Receptor Agonists and druglike angiotensin II compounds with affinity for the AT2 receptor.
Uses
1-(Dimethylsulfamoyl)imidazole may be used to synthesize 1-(dimethylsulfamoyl)-2-imidazolecarboxaldehyde.
General Description
1-(Dimethylsulfamoyl)imidazole is an imidazole derivative.
Synthesis
288-32-4
13360-57-1
78162-58-0
The general procedure for the synthesis of N,N-dimethylimidazole-1-sulfonamide from imidazole and N,N-dimethylaminosulfonyl chloride is as follows: with reference to Example 7-1 N,N-dimethyl-1H-imidazole-1-sulfonamide, imidazole (5.00 g, 73.6 mmol) was dissolved in toluene (80 ml), followed by the addition of triethylamine (9.52 ml, 68.4 mmol) and N,N-dimethylaminosulfonyl chloride (6.77 ml, 63.3 mmol). The reaction mixture was stirred at room temperature for 8 hours. After completion of the reaction, the precipitate was removed by filtration and the filtrate was concentrated under reduced pressure. The resulting residue was subjected to azeotropic distillation with hexane to give the final N,N-dimethylimidazole-1-sulfonamide (10.9 g, 98% yield). The product was characterized by 1H NMR (CDCl3, 400 MHz) with δ-values of 7.87 (s, 1H), 7.23 (d, 1H, J = 1.4 Hz), 7.11 (d, 1H, J = 1.4 Hz), 2.82 (s, 6H).
References
[1] Patent: EP1647546, 2006, A1. Location in patent: Page/Page column 30
[2] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984, # 3, p. 481 - 486
[3] Organic Letters, 2005, vol. 7, # 5, p. 929 - 931
[4] Tetrahedron, 2007, vol. 63, # 4, p. 947 - 952
[5] Journal of the Iranian Chemical Society, 2012, vol. 9, # 6, p. 951 - 955
IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
View Lastest Price from IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-30 | IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE
78162-58-0
|
US $0.00-0.00 / kg | 1kg | 95% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | |
 |
2025-12-29 | IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE
78162-58-0
|
US $0.00 / kg | 1kg | 97% | As your request | Changzhou waston chemical technology Co.,Ltd | |
 |
2025-11-18 | IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE USP/EP/BP
78162-58-0
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE
78162-58-0
- US $0.00-0.00 / kg
- 95%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE
78162-58-0
- US $0.00 / kg
- 97%
- Changzhou waston chemical technology Co.,Ltd
-
- IMIDAZOLE-1-SULFONIC ACID DIMETHYL AMINE USP/EP/BP
78162-58-0
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
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