2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
- CAS No.
- 62732-44-9
- Chemical Name:
- 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
- Synonyms
- Takinocrine;Brn 0475930;MFCD11052605;AKOS MSC-0106;AURORA KA-7699;Unii-cv71vtp0vn;CBI-BB ZERO/005050;Ipidacrine, 10 mM in DMSO;8-Hexahydro-1H-cyclopenta[b]quinolin-9-ylaMine;2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-
- CBNumber:
- CB3740985
- Molecular Formula:
- C12H16N2
- Molecular Weight:
- 188.27
- MDL Number:
- MFCD00618424
- MOL File:
- 62732-44-9.mol
Melting point | 202-203 °C(Solv: methanol (67-56-1); water (7732-18-5)) |
---|---|
Boiling point | 368.0±42.0 °C(Predicted) |
Density | 1.170±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMF: 25 mg/ml,DMSO: 25 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml |
form | A solid |
pka | 10.88±0.20(Predicted) |
color | White to off-white |
EWG's Food Scores | 1 |
FDA UNII | CV71VTP0VN |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H335-H319-H315 | |||||||||
Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
Hazard Codes | Xi | |||||||||
Hazard Note | Irritant | |||||||||
NFPA 704 |
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2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | I739330 | Ipidacrine | 62732-44-9 | 1g | $870 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 46880 | Ipidacrine | 62732-44-9 | 10g | $2000 | 2021-12-16 | Buy |
Matrix Scientific | 134023 | 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine 95%+ | 62732-44-9 | 2.500g | $324 | 2021-12-16 | Buy |
Matrix Scientific | 134023 | 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine 95%+ | 62732-44-9 | 100mg | $58 | 2021-12-16 | Buy |
Matrix Scientific | 134023 | 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine 95%+ | 62732-44-9 | 500mg | $112 | 2021-12-16 | Buy |
2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Chemical Properties,Uses,Production
Uses
Ipidacrine is used in biological studies as a possible treatment of toxic cognitive disorders.
Definition
ChEBI: 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine is an aminoquinoline.
in vivo
Ipidacrine (1 mg/kg, p.o., repeated and a single dose for 5 days) by repeated administration has more potent antiamnesic effects than by single administration in induced by nucleus basalis of meynert (NBM) induced rats[1].
Ipidacrine (10 mg/kg p.o., a single dose) significantly decreases spontaneous movements, which is more selective as an antiamnesic than either Tacrine (HY-111338) and E-2020 (HY-B0034) in rats[1].
Ipidacrine (6.7 mg/kg, intragastrically, daily for 14 days) leads to statistically more efficient evolving of intracavernous pressure (ICPmax)/maxipressure (MAP) compared with control group in Streptozotocin (STZ) (HY-13753)-induced diabetic rats[3].
Animal Model: | Rats[1] |
Dosage: | 1 mg/kg |
Administration: | p.o., repeated and a single dose for 5 days |
Result: | The repeated administration of ipidacrine improved amnesia induced by nucleus basalis of meynert (NBM) lesions in the passive avoidance task in rats. |
Animal Model: | Rats[1] |
Dosage: | 3, 10, 30 mg/kg |
Administration: | p.o., a single dose |
Result: | Decreased pupil size and increased salivation at 3 mg/kg, decreased spontaneous movements at 10 mg/kg and decreased body temperature and induced tremor at 30 mg/kg in rats. |
Animal Model: | Rats with streptozotocin (STZ) (HY-13753) induced diabetes mellitus-induced erectile dysfunction (DMED)[1] |
Dosage: | 6.7 mg/kg |
Administration: | crushed, suspended in 1% starch solution and administered intragastrically daily for 14 days |
Result: | Ipidacrine was as effective as sildenafil and could significantly improve DMED symptoms. |
2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32432 | 58 |
RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3390 | 58 |
changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9644 | 58 |
Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24727 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49977 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 10997 | 58 |
View Lastest Price from 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-10-07 | 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
62732-44-9
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
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2025-09-11 | Ipidacrine
62732-44-9
|
US $29.00-0.00 / mg | 97.73% | 10g | TargetMol Chemicals Inc. | ||
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2019-07-06 | 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
62732-44-9
|
US $1000.00 / KG | 1KG | 99% | 10KG | Career Henan Chemical Co |
-
- 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
62732-44-9
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Ipidacrine
62732-44-9
- US $29.00-0.00 / mg
- 97.73%
- TargetMol Chemicals Inc.
-
- 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
62732-44-9
- US $1000.00 / KG
- 99%
- Career Henan Chemical Co
62732-44-9(2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE)Related Search:
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