ChemicalBook >> CAS DataBase List >>2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE

CAS No.
62732-44-9
Chemical Name:
2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
Synonyms
Takinocrine;Brn 0475930;MFCD11052605;AKOS MSC-0106;AURORA KA-7699;Unii-cv71vtp0vn;CBI-BB ZERO/005050;Ipidacrine, 10 mM in DMSO;8-Hexahydro-1H-cyclopenta[b]quinolin-9-ylaMine;2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-
CBNumber:
CB3740985
Molecular Formula:
C12H16N2
Molecular Weight:
188.27
MDL Number:
MFCD00618424
MOL File:
62732-44-9.mol
Last updated:2025-09-11 22:01:37

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Properties

Melting point 202-203 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling point 368.0±42.0 °C(Predicted)
Density 1.170±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: 25 mg/ml,DMSO: 25 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
form A solid
pka 10.88±0.20(Predicted)
color White to off-white
EWG's Food Scores 1
FDA UNII CV71VTP0VN

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
Hazard Note  Irritant
NFPA 704
0
2 0

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC I739330 Ipidacrine 62732-44-9 1g $870 2021-12-16 Buy
Medical Isotopes, Inc. 46880 Ipidacrine 62732-44-9 10g $2000 2021-12-16 Buy
Matrix Scientific 134023 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine 95%+ 62732-44-9 2.500g $324 2021-12-16 Buy
Matrix Scientific 134023 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine 95%+ 62732-44-9 100mg $58 2021-12-16 Buy
Matrix Scientific 134023 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine 95%+ 62732-44-9 500mg $112 2021-12-16 Buy
Product number Packaging Price Buy
I739330 1g $870 Buy
46880 10g $2000 Buy
134023 2.500g $324 Buy
134023 100mg $58 Buy
134023 500mg $112 Buy

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Chemical Properties,Uses,Production

Uses

Ipidacrine is used in biological studies as a possible treatment of toxic cognitive disorders.

Definition

ChEBI: 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine is an aminoquinoline.

in vivo

Ipidacrine (1 mg/kg, p.o., repeated and a single dose for 5 days) by repeated administration has more potent antiamnesic effects than by single administration in induced by nucleus basalis of meynert (NBM) induced rats[1].
Ipidacrine (10 mg/kg p.o., a single dose) significantly decreases spontaneous movements, which is more selective as an antiamnesic than either Tacrine (HY-111338) and E-2020 (HY-B0034) in rats[1].
Ipidacrine (6.7 mg/kg, intragastrically, daily for 14 days) leads to statistically more efficient evolving of intracavernous pressure (ICPmax)/maxipressure (MAP) compared with control group in Streptozotocin (STZ) (HY-13753)-induced diabetic rats[3].

Animal Model:Rats[1]
Dosage:1 mg/kg
Administration:p.o., repeated and a single dose for 5 days
Result:The repeated administration of ipidacrine improved amnesia induced by nucleus basalis of meynert (NBM) lesions in the passive avoidance task in rats.
Animal Model:Rats[1]
Dosage:3, 10, 30 mg/kg
Administration:p.o., a single dose
Result:Decreased pupil size and increased salivation at 3 mg/kg, decreased spontaneous movements at 10 mg/kg and decreased body temperature and induced tremor at 30 mg/kg in rats.
Animal Model:Rats with streptozotocin (STZ) (HY-13753) induced diabetes mellitus-induced erectile dysfunction (DMED)[1]
Dosage:6.7 mg/kg
Administration:crushed, suspended in 1% starch solution and administered intragastrically daily for 14 days
Result:Ipidacrine was as effective as sildenafil and could significantly improve DMED symptoms.

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 71)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29852 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32432 58
RongNa Biotechnology Co.,Ltd
+86-86-13583358881 +8618560316533 Brad@rongnabiotech.com China 3390 58
changzhou huayang technology co., ltd
+8615250961469 2571773637@qq.com China 9644 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 24727 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39031 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49977 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8615965530500 nickzhang@hangyubiotech.com China 10997 58

View Lastest Price from 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE pictures 2025-10-07 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
62732-44-9
0.99 RongNa Biotechnology Co.,Ltd
Ipidacrine pictures 2025-09-11 Ipidacrine
62732-44-9
US $29.00-0.00 / mg 97.73% 10g TargetMol Chemicals Inc.
	2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE pictures 2019-07-06 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
62732-44-9
US $1000.00 / KG 1KG 99% 10KG Career Henan Chemical Co
  • Ipidacrine pictures
  • Ipidacrine
    62732-44-9
  • US $29.00-0.00 / mg
  • 97.73%
  • TargetMol Chemicals Inc.

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Spectrum

9-Amino-2,3,5,6,7,8-hexahydro-1H-cyclopenta(b)quinoline monohydrochloride MFCD11052605 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine CBI-BB ZERO/005050 AURORA KA-7699 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE 9-AMINO-2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLINE AKOS MSC-0106 2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9- 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride hydrate 9-Amino-2,3,5,6,7,8-hexahydro-1H-cyclopentaxinolina monohydrate 2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine Takinocrine 1H-Cyclopenta(B)quinolin-9-amine, 2,3,5,6,7,8-hexahydro- Brn 0475930 Unii-cv71vtp0vn 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine(SALTDATA: HCl H2O) 8-Hexahydro-1H-cyclopenta[b]quinolin-9-ylaMine 1H-Cyclopenta(b)quinoline, 2,3,5,6,7,8-hexahydro-9-amino-, monohydrochloride 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-ylamine hydrochloride 2,3,5,6,7,8-Hexahydro-9-amino-1H-cyclopenta(b)quinoline hydrochloride Ipidacrine,inhibit,cholinesterase,nootropic,Inhibitor,Cholinesterase (ChE),Alzheimer disease Ipidacrine, 10 mM in DMSO 62732-44-9