2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER
- CAS No.
- 197376-47-9
- Chemical Name:
- 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER
- Synonyms
- Ethyl 2-Chloropyridine-5-acetate;Ethyl 6-Chloropyridine-3-acetate;2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL;ETHYL (6-CHLOROPYRIDIN-3-YL)-ACETATE;Ethyl 2-(6-chloropyridin-3-yl)acetate;2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER;6-Chloro-3-pyridineacetic acid ethyl ester;3-Pyridineacetic acid, 6-chloro-, ethyl ester;2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER ISO 9001：2015 REACH
- CBNumber:
- CB3758232
- Molecular Formula:
- C9H10ClNO2
- Molecular Weight:
- 199.63
- MDL Number:
- MFCD03092921
- MOL File:
- 197376-47-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| ETHYL (6-CHLOROPYRIDIN-3-YL)-ACETATE 97% | 61900 | 0.25G | $39 |
| ETHYL (6-CHLOROPYRIDIN-3-YL)-ACETATE 97% | 61900 | 1G | $89 |
| ETHYL (6-CHLOROPYRIDIN-3-YL)-ACETATE 97% | 61900 | 5G | $290 |
| Ethyl 6-Chloropyridine-3-acetate 95% | E49806 | 250mg | $61 |
| Ethyl 6-Chloropyridine-3-acetate 95% | E49806 | 1g | $70 |
| Boiling point | 285.8±25.0 °C(Predicted) |
|---|---|
| Density | 1.217±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | -0.34±0.10(Predicted) |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C9H10ClNO2/c1-2-13-9(12)5-7-3-4-8(10)11-6-7/h3-4,6H,2,5H2,1H3 |
| InChIKey | HNMKCAOYIPYXRD-UHFFFAOYSA-N |
| SMILES | C1=NC(Cl)=CC=C1CC(OCC)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 61900 | ETHYL (6-CHLOROPYRIDIN-3-YL)-ACETATE 97% | 197376-47-9 | 0.25G | $39 | 2026-04-30 | Buy |
| AstaTech | 61900 | ETHYL (6-CHLOROPYRIDIN-3-YL)-ACETATE 97% | 197376-47-9 | 1G | $89 | 2026-04-30 | Buy |
| AstaTech | 61900 | ETHYL (6-CHLOROPYRIDIN-3-YL)-ACETATE 97% | 197376-47-9 | 5G | $290 | 2026-04-30 | Buy |
| Synthonix | E49806 | Ethyl 6-Chloropyridine-3-acetate 95% | 197376-47-9 | 250mg | $61 | 2026-05-06 | Buy |
| Synthonix | E49806 | Ethyl 6-Chloropyridine-3-acetate 95% | 197376-47-9 | 1g | $70 | 2026-05-06 | Buy |
2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER Chemical Properties,Uses,Production
Synthesis
64-17-5
39891-13-9
197376-47-9
The general procedure for the synthesis of ethyl 2-(6-chloropyridin-3-yl)acetate from ethanol and 2-chloropyridine-5-acetic acid was as follows: to an ethanolic solution of 6-chloro-3-pyridineacetic acid (1 g, 5.83 mmol) was slowly added concentrated sulfuric acid (1.6 mL). The reaction mixture was heated to reflux and kept for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated in a rotary evaporator to remove most of the ethanol. The concentrated residue was dissolved in ethyl acetate and subsequently washed with saturated sodium bicarbonate solution to neutralize the residual acid. The organic phase was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give the crude product. Finally, the crude product was purified by silica gel column chromatography to afford ethyl 2-(6-chloropyridin-3-yl)acetate (1.1 g, 95% yield).
References
[1] Patent: WO2013/13817, 2013, A1. Location in patent: Page/Page column 99
[2] Patent: WO2013/13815, 2013, A1. Location in patent: Page/Page column 147
[3] Patent: US2013/29961, 2013, A1. Location in patent: Paragraph 0664
[4] Patent: US2013/29962, 2013, A1. Location in patent: Paragraph 0815
[5] Chemical Communications, 2015, vol. 51, # 84, p. 15446 - 15449
2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18895 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5899 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
View Lastest Price from 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL
197376-47-9
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-01-10 | 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER
197376-47-9
|
US $1.00 / KG | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL
197376-47-9
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 2-CHLOROPYRIDINE-5-ACETIC ACID ETHYL ESTER
197376-47-9
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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