Glutaraldehyde
- CAS No.
- 111-30-8
- Chemical Name:
- Glutaraldehyde
- Synonyms
- glutaral;Gluteraldehyde;GLUTARIC DIALDEHYDE;1,5-PENTANEDIAL;Pentanedial;GDA;Glutaraldehyd;GLUTARDIALDEHYDE;Aqucar;Ucarcide
- CBNumber:
- CB3762723
- Molecular Formula:
- C5H8O2
- Molecular Weight:
- 100.12
- MDL Number:
- MFCD00007025
- MOL File:
- 111-30-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Glutaric dialdehyde solution 50 wt. % in H2O, FCC | W512303 | 1 each | $61.6 |
| Glutaric dialdehyde solution 50?wt. % in H2O, FCC | W512303 | 1kg | $85.1 |
| Glutaric dialdehyde solution 50?wt. % in H2O, FCC | W512303 | 10Kg | $448 |
| Glutardialdehyde (25% solution in water) for synthesis | 8.20603 | 100mL | $39.6 |
| Glutardialdehyde (25% solution in water) for synthesis | 8.20603 | 1L | $61.6 |
| More product size | |||
| Melting point | -15 °C |
|---|---|
| Boiling point | 100 °C |
| Density | 1.058 g/mL at 20 °C |
| vapor density | 1.05 (vs air) |
| vapor pressure | 15 mmHg ( 20 °C) |
| FLAVIS Number | 05.149 | Glutaraldehyde |
| refractive index |
n |
| Flash point | 100°C |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solution |
| color | Clear to slight haze |
| Specific Gravity | 1.06 |
| Odor | pungent aldehyde odor |
| PH | >3.0 (H2O, 20°C) |
| biological source | synthetic |
| Water Solubility | miscible |
| Merck | 14,4472 |
| BRN | 605390 |
| Henry's Law Constant | 3.0×102 mol/(m3Pa) at 25℃, Olson (1998) |
| Exposure limits | Ceiling (ACGIH) 0.8 mg/m3 (0.2 ppm). |
| Stability | Light Sensitive |
| Cosmetics Ingredients Functions |
FRAGRANCE PRESERVATIVE |
| Cosmetic Ingredient Review (CIR) | Glutaraldehyde (111-30-8) |
| InChI | 1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2 |
| InChIKey | SXRSQZLOMIGNAQ-UHFFFAOYSA-N |
| SMILES | [H]C(CCCC([H])=O)=O |
| LogP | -0.180 (est) |
| Toxicology and Carcinogenesis | Toxicology and Carcinogenesis Studies of Glutaraldehyde (CASRN 111-30-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) |
| Substances of Very High Concern (SVHC) Candidate List | glutaral (111-30-8) |
| Substances Added to Food (formerly EAFUS) | GLUTARALDEHYDE |
| FDA 21 CFR | 173.357; 175.105; 176.300 |
| CAS DataBase Reference | 111-30-8(CAS DataBase Reference) |
| EWG's Food Scores | 3-6 |
| FDA UNII | T3C89M417N |
| NIST Chemistry Reference | Glutaral(111-30-8) |
| Pesticides Freedom of Information Act (FOIA) | Glutaraldehyde,Sporicidin |
| EPA Substance Registry System | Glutaraldehyde (111-30-8) |
| Toxicological Profile|ATSDR | Glutaraldehyde|Toxicological Profile|ATSDR |
| UNSPSC Code | 41116133 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS06,GHS08,GHS09 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H331-H312-H314-H317-H334-H335-H411 | |||||||||
| Precautionary statements | P261-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | T,N,Xn | |||||||||
| Risk Statements | 36/37/38-42/43-34-23-22-50-23/25-41-37/38-20/22 | |||||||||
| Safety Statements | 23-26-36/37-45-36/37/39-61 | |||||||||
| RIDADR | UN 2922 8/PG 2 | |||||||||
| OEL | Ceiling: 0.2 ppm (0.8 mg/m3) (Aldehydes) | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | MA2450000 | |||||||||
| F | 8-10-23 | |||||||||
| Autoignition Temperature | 395°C | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29121900 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 4 Inhalation Acute Tox. 4 Oral Aquatic Chronic 3 Eye Dam. 1 Repr. 1B Resp. Sens. 1 Skin Corr. 1B Skin Sens. 1 STOT SE 3 |
|||||||||
| Hazardous Substances Data | 111-30-8(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 of 25% soln orally in rats: 2.38 ml/kg; by skin penetration in rabbits: 2.56 ml/kg (Smyth) | |||||||||
| NFPA 704 |
|
Glutaraldehyde price More Price(73)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W512303 | Glutaric dialdehyde solution 50 wt. % in H2O, FCC | 111-30-8 | 1 each | $61.6 | 2026-03-19 | Buy |
| Sigma-Aldrich | W512303 | Glutaric dialdehyde solution 50?wt. % in H2O, FCC | 111-30-8 | 1kg | $85.1 | 2026-03-19 | Buy |
| Sigma-Aldrich | W512303 | Glutaric dialdehyde solution 50?wt. % in H2O, FCC | 111-30-8 | 10Kg | $448 | 2026-03-19 | Buy |
| Sigma-Aldrich | 8.20603 | Glutardialdehyde (25% solution in water) for synthesis | 111-30-8 | 100mL | $39.6 | 2026-03-19 | Buy |
| Sigma-Aldrich | 8.20603 | Glutardialdehyde (25% solution in water) for synthesis | 111-30-8 | 1L | $61.6 | 2026-03-19 | Buy |
Glutaraldehyde Chemical Properties,Uses,Production
Uses
As broad-spectrum antimicrobial cold sterilant/disinfectant for hospital equipment; as tanning agent for leather; as tissue fixative; as cross-linking agent for proteins; as preservative in cosmetics; as therapeutic agent for warts, hyperhidrosis, and dermal mycotic infections; in X ray processing solutions and film emulsion; as a disinfectant in the beauty industry
Description
Glutaraldehyde is a well-known sensitizer among cleaners and health workers. It is also found in X-ray developers products.
Chemical Properties
Glutaraldehyde is a colorless liquid with a pungent odor, which readily changes to a glossy polymer. The Odor Threshold is 0.04 ppm (NY) and 0.2 ppm (NJ). It is miscible in water and organic solvents. Glutaraldehyde may be incompatible with strong oxidizers and strong bases. It should be noted that alkaline solutions containing glutaraldehyde may react with alcohol, ketones, amines, hydrazines, and proteins.
Uses
glutaral (glutardialdehyde) is a broad-spectrum preservative that can cause skin irritation. This is an amino acid occurring in green sugar beets.
Uses
Glutaraldehyde (Symbol GTA; glutaric dialdehyde, 1,5-pentanedial, glutaral) is commonly used in the medical industry in cold sterilization and in the X-ray development process. It can also be encountered in the leather industry as a tanning ingredient and in mortuary workers. There are no reports which indicate that glutaraldehyde is a naturally occurring compound. Cidex and Acusol, 2% buffered solutions, use this aldehyde as an active ingredient. Sodium bicarbonate is required to activate the solution, which then has a shelf life of 1–2 weeks. Despite health hazards involved with its use, glutaraldehyde is one of the most effective biocides used. It is particularly effective against bacteria and viruses, including the human immunodeficiency virus.
Uses
Glutaraldehyde is used to disinfect medical and dental equipment. Glutaraldehyde is also used for industrial water treatment and as a preservative.
Uses
Glutaraldehyde is used as a cold sterilizingdisinfectant, as fixatives for tissues, in tanning,and in cross-linking proteins.
Definition
ChEBI: A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
Synthesis Reference(s)
Tetrahedron, 48, p. 3503, 1992 DOI: 10.1016/S0040-4020(01)88489-1
General Description
Light yellow liquid. Mixes with water.
Air & Water Reactions
Polymerizes in the presence of water.
Reactivity Profile
GLUTARALDEHYDE may discolor on exposure to air. Pentanedial polymerizes on heating. Pentanedial is incompatible with strong oxidizing agents. Pentanedial polymerizes in the presence of water.
Health Hazard
Glutaraldehyde is a strong irritant to the nose,eyes, and skin. In rabbits, 250 μg and 500 mg in 24 hours produced severe irritation in theeyes and skin, respectively. The corrosiveeffect on human skin of 6 mg over 3 dayswas severe. However, the acute toxicity ofglutaraldehyde by the oral and dermal routesis low to mild. Ohsumi and Kuroki (1988)determined that the symptoms of acute toxicityof this compound were less severethan those of formaldehyde. But the restraintof growth was more pronounced in micetreated with glutaraldehyde. An oral LD50value of 1300 mg/kg was reported for mice.Inhalation of this compound can cause upperrespiratory tract irritation, headache, and nervousness.Mice exposed at 33 ppm showedsymptoms of hepatitis.
Fire Hazard
Literature sources indicate that Pentanedial is nonflammable.
Flammability and Explosibility
Non flammable
Biochem/physiol Actions
Glutaraldehyde is an effective protein crosslinker and finds application in techniques like enzyme immobilisation microscopy, histochemistry and cytochemistry. It exists in different forms under acidic or neutral conditions. It is a biocide widely used as a disinfectant in hospitals and industries and is toxic to aquatic organisms. Its allergic nature leads to hypersensitivity reactions. Contact of glutaraldehyde vapors in endoscopy contributes to Colitis.
Contact allergens
Glutaraldehyde is a well-know sensitizer in cleaners and health workers. It can also be found in X-ray developers or in cosmetics.
Safety Profile
Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by inhalation, skin contact, and subcutaneous routes. Experimental teratogenic and reproductive effects. A severe eye and human skin irritant. Mutation data reported. When heated to decomp osition it emits acrid smoke and irritating fumes. See also ALDEHYDES.
Synthesis
At present, the synthesis methods of glutaraldehyde mainly include pyridine method, pentanediol oxidation method, reduction method, pyran method, cyclopentene oxidation method, pyridine method is to reduce dihydropyridine with sodium metal and methanol and then open the ring of glutaraldehyde oxime by hydroxylamine hydrochloride, then decompose the glutaraldehyde by sodium nitrite and hydrochloric acid, the process route is long, consume a lot of pollution, the cost is no longer suitable for the production of the use of pentanediol oxidation, the depth of oxidation of the reaction The depth of oxidation is not easy to control, and glutaraldehyde is very easy to oxidize, resulting in the existence of low product yield, high cost and other determinations; cyclopentene oxidation method, the use of acid-catalyzed hydrogen peroxide oxidation of cyclopentadiene, with the study of non-homogeneous catalysts, the method embodies a great potential, but at present there is still a catalyst to set up a small number of times, the shortcomings of the lower conversion rate of glutaraldehyde, temporarily unable to meet the requirements of the industrialization; pyran method, the use of acetylene and aliphatic alcohols to produce Vinyl ether, then vinyl ether and acrolein reaction to synthesize 2-alkoxy-3.4-dihydropyran, and then hydrolyzed to glutaraldehyde. The pyran method is relatively mature, with mild reaction conditions, simple operation, good product quality, high yield, little environmental pollution, and suitable for industrial production.
Potential Exposure
Glutaraldehyde is used in leather tanning; in embalming fluids; as a germicide; as a cross-linking agent for protein and polyhydroxy materi als; as a fixative for tissues; and as an intermediate. Buffered solutions are used as antimicrobial agents in hospitals.
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Purification Methods
Likely impurities are oxidation products-acids, semialdehydes and polymers. It can be purified by repeated washing with activated charcoal (Norit) followed by vacuum filtration, using 15-20g charcoal/100mL of glutaraldehyde solution. Distil it at 60-65o/15mm, discarding the first 5-10%, then dilute with an equal volume of freshly distilled water at 70-75o, using magnetic stirring under nitrogen. The solution is stored at low temperature (3-4o), in a tightly stoppered container, and protected from light. Standardise by titration with hydroxylamine. [Anderson J Histochem Cytochem 15 652 1967, Beilstein 1 IV 3659.]
Incompatibilities
Water contact forms a polymer solution. A strong reducing agent. Incompatible with strong acids; caustics, ammonia, amines, and strong oxidizers. Note: Alkaline solutions of glutaraldehyde (i.e., activated glutar aldehyde) react with alcohol, ketones, amines, hydrazines, and proteins.
Toxics Screening Level
There are two Initial Threshold Screening Levels* (ITSLs) for glutaraldehyde:
0.08 μg/m3 with annual averaging time for chronic exposures
2 μg/m3 with 1-hour averaging time for acute exposures.
Waste Disposal
Dissolve or mix the material with a combustible solvent and burn in a chemical incinera tor equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.
Glutaraldehyde Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zouping mingyuan import & export trading co., ltd | +86-0543-2240078 +8618364991597 | myzhao793@163.com | China | 981 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Hebei ZB Gamay Biological Technology Co.,Ltd | +8617330018573 | info@zbvet.net | China | 263 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Wuhan Quanjinci New Material Co.,Ltd. | +86-15271838296; +8615271838296 | kyra@quanjinci.com | China | 1512 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Chongqing Soarwin Technology Co., Ltd | +86-15790943001 | crystal@sorawin.cn | China | 421 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
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View Lastest Price from Glutaraldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-23 | Glutaraldehyde
111-30-8
|
US $0.00 / KG | 500g | 50% 25% | 5000mt | Jinan Finer Chemical Co., Ltd | |
 |
2026-04-22 | Glutaraldehyde
111-30-8
|
US $3850.00 / T | 1T | 98% | 10-200mt | Baoji Guokang Healthchem Co., Ltd. | |
 |
2026-03-20 | Glutaraldehyde
111-30-8
|
US $10.00 / kg | 1kg | 99.5% | 100 | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Glutaraldehyde
111-30-8
- US $0.00 / KG
- 50% 25%
- Jinan Finer Chemical Co., Ltd
-
- Glutaraldehyde
111-30-8
- US $3850.00 / T
- 98%
- Baoji Guokang Healthchem Co., Ltd.
-
- Glutaraldehyde
111-30-8
- US $10.00 / kg
- 99.5%
- Hebei Chuanghai Biotechnology Co., Ltd
