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(R)-N-BOC-3-AMINOBUTYRIC ACID

(R)-N-BOC-3-AMINOBUTYRIC ACID Structure
(R)-N-BOC-3-AMINOBUTYRIC ACID structure
CAS No.
159991-23-8
Chemical Name:
(R)-N-BOC-3-AMINOBUTYRIC ACID
Synonyms
(R)-3-((tert-Butoxycarbonyl)aMino)butanoic acid;(3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid;Boc-d-β-hoala-oh;BOC-D-B-HOMOALA-OH;(R)-BOC-B2-HOALA-OH;RARECHEM AK PT F080;Boc-D-b-homoalanine;Boc-D-β-Homo-Ala-OH;Boc-D-beta-HoAla-OH;Boc-D-β-Homoalanine
CBNumber:
CB3763836
Molecular Formula:
C9H17NO4
Molecular Weight:
203.24
MDL Number:
MFCD00270343
MOL File:
159991-23-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:30:42
Product description Number Pack Size Price
Boc-D-beta-homoalanine Asreported 265644 250mg $358
Boc-D-beta-homoalanine Asreported 265644 500mg $496
Boc-D-beta-homoalanine Asreported 265644 1g $872
Boc-D-beta-homoalanine Asreported 265644 2g $1234
Boc-D-beta-homoalanine Asreported 265644 5g $1769
More product size
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(R)-N-BOC-3-AMINOBUTYRIC ACID Properties

Melting point 104-107 °C
Boiling point 339.5±25.0 °C(Predicted)
Density 1.101±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
pka 4.43±0.10(Predicted)
Appearance White to off-white Solid
optical activity Consistent with structure
InChI InChI=1S/C9H17NO4/c1-6(5-7(11)12)10-8(13)14-9(2,3)4/h6H,5H2,1-4H3,(H,10,13)(H,11,12)/t6-/m1/s1
InChIKey PYNDHEONPQYIAN-ZCFIWIBFSA-N
SMILES C(O)(=O)C[C@H](NC(OC(C)(C)C)=O)C
CAS DataBase Reference 159991-23-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Flame (GHS02)
GHS07,GHS02
Signal word  Warning
Hazard statements  H315-H319-H226
Precautionary statements  P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235
Hazard Codes  T
Risk Statements  25
Safety Statements  45
REACH Registrations Active
NFPA 704
0
0 0

(R)-N-BOC-3-AMINOBUTYRIC ACID price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 265644 Boc-D-beta-homoalanine Asreported 159991-23-8 250mg $358 2026-06-03 Buy
Usbiological 265644 Boc-D-beta-homoalanine Asreported 159991-23-8 500mg $496 2026-06-03 Buy
Usbiological 265644 Boc-D-beta-homoalanine Asreported 159991-23-8 1g $872 2026-06-03 Buy
Usbiological 265644 Boc-D-beta-homoalanine Asreported 159991-23-8 2g $1234 2026-06-03 Buy
Usbiological 265644 Boc-D-beta-homoalanine Asreported 159991-23-8 5g $1769 2026-06-03 Buy
Product number Packaging Price Buy
265644 250mg $358 Buy
265644 500mg $496 Buy
265644 1g $872 Buy
265644 2g $1234 Buy
265644 5g $1769 Buy

(R)-N-BOC-3-AMINOBUTYRIC ACID Chemical Properties,Uses,Production

Chemical Properties

Off-white powder

Uses

(R)-3-(tert-Butoxycarbonylamino)butanoic Acid is a non-proteinogenic amino acid that can be used to synthesize peptide analogs.

Synthesis

(R)-3-AMINOBUTYRIC ACID

3775-73-3

Di-tert-butyl dicarbonate

24424-99-5

(R)-N-BOC-3-AMINOBUTYRIC ACID

159991-23-8

General steps: 1. suspend (R)-3-aminobutyric acid (2.415 g, 23.42 mmol) in a solvent mixture of dioxane (15 mL) and water (15.00 mL) at room temperature with stirring. 2. Triethylamine (TEA, 4.90 mL, 35.1 mmol) was added dropwise to the suspension to give a light brown solution. 3. The reaction mixture was cooled to 0 °C and di-tert-butyl dicarbonate (4.69 g, 26.9 mmol) was added in one portion. 4. The reaction mixture was stirred at room temperature for 16 hours. 5. 5. Upon completion of the reaction, the mixture was partitioned between water (80 mL) and ethyl acetate (EtOAc, 80 mL). 6. The aqueous layer was separated and washed with EtOAc. 7. The aqueous layer was acidified to pH=3 with 1 M aqueous KHSO4 and extracted with EtOAc (2 x 80 mL). 8. The EtOAc extracts were combined, washed with saturated aqueous NaCl (2 x 80 mL), dried over anhydrous Na2SO4, filtered and concentrated. 9. (R)-3-((tert-butoxycarbonyl)amino)butyric acid (4.301 g, 21.16 mmol, 90% yield) was obtained as a pale yellow solid. 10. The product was characterized by XH NMR (400 MHz, CDCl3): δ 4.92 (s, 1H), 4.14-3.96 (m, 2H), 2.56 (d, J=5.2 Hz, 2H), 1.45 (s, 9H), 1.25 (d, J=6.9 Hz, 3H).

References

[1] Patent: WO2012/125622, 2012, A1. Location in patent: Page/Page column 135-136
[2] Chinese Chemical Letters, 2015, vol. 26, # 1, p. 103 - 107
[3] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 5, p. 1421 - 1425
[4] Angewandte Chemie - International Edition, 2018, vol. 57, # 31, p. 9707 - 9710
[5] Angew. Chem., 2018, vol. 130, # 31, p. 9855 - 9858,4

(R)-N-BOC-3-AMINOBUTYRIC ACID Preparation Products And Raw materials

Raw materials

(R)-3-AMINOBUTYRIC ACID 3-t-butoxycarbonylaminobutyric acid Di-tert-butyl dicarbonate rac-3-AMinoisobutyric Acid Hydrochloride Carbonic acid, bis(1,1-dimethylethyl) ester
1,4-Dioxane Water Triethylamine

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Preparation Products

(R)-N-BOC-3-AMINOBUTYRIC ACID Suppliers

Global( 156)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Taizhou Tianhong Biochemistry Technology Co., Ltd. 		0523-86132544 sales@thbiochem.com CHINA 305 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
Nanjing Fred Technology Co., Ltd. 		+86-02584696168 15380713688 Austin@fredchem.cn CHINA 865 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14304 58
GL Biochem(Binhai) Ltd. 		+86-021-61263370 +8615301650015 wuqiuyan@glschina.com China 2975 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Taizhou Tianhong Biochemistry Technology Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Nanjing Fred Technology Co., Ltd. 		58
Win-Win chemical CO., Limited 		58
GL Biochem(Binhai) Ltd. 		58
ANHUI WITOP BIOTECH CO., LTD 		58

View Lastest Price from (R)-N-BOC-3-AMINOBUTYRIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-N-BOC-3-AMINOBUTYRIC ACID pictures 2026-05-05 (R)-N-BOC-3-AMINOBUTYRIC ACID
159991-23-8
 $150.00-1500.00 1KG 0.99 20 tons Zibo Hangyu Biotechnology Development Co., Ltd

(R)-N-BOC-3-AMINOBUTYRIC ACID Spectrum

(R)-N-BOC-3-AMINOBUTYRIC ACID(159991-23-8)1HNMR

159991-23-8((R)-N-BOC-3-AMINOBUTYRIC ACID)Related Search:

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BOC-D-BETA-HOMOALANINE BOC-D-B-HOMOALA-OH BOC PROTECTED (R)-B-AMINOBUTYRIC ACID (R)-N-BOC-3-AMINOBUTYRIC ACID (R)-N-(TERT-BUTOXYCARBONYL)-3-AMINOBUTYRIC ACID 3-N-BOC-3-(R)-AMINO BUTYRIC ACID (3R)-3-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]butanoic acid (3R)-3-{[(tert-butoxy)carbonyl]amino}butanoic acid (R)-BOC-B2-HOALA-OH (R)-BOC-BETA2-HAL-OH (R)-BOC-BETA2-HOMOALANINE RARECHEM AK PT F080 (R)-3-TERT-BUTOXYCARBONYLAMINO-BUTYRIC ACID (R)-3-(BOC-AMINO)-BUTYRIC ACID Butanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (3R)- (9CI) (R)-3-((tert-Butoxycarbonyl)aMino)butanoic acid Boc-D-b-homoalanine Boc-D-β-Homo-Ala-OH (R)-3-(Boc-amino)butanoic acid Boc-D-BETA-Homo-Ala-OH Boc-D-beta-HoAla-OH (R)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]butanoic acid Boc-D-β-homoalanine≥ 98% (HPLC) (Tert-Butoxy)Carbonyl D-β-homoalanine (R)-3-(Boc-amino)butyric acid, 98% white powder Butanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (3R)- N-β-(t-Butoxycarbonyl)-D-β-homoalanine (R)-3-amino-butanoicacidmethylester HCl Boc-d-β-hoala-oh Boc-D-β-Homoalanine (3R)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]butanoic acid Boc-R-3-Aminobutyric acid (R)-N-BOC-3-AMINOBUTYRIC ACID, 98%min (3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid 159991-23-8 Amino Acid N-BOC Beta amino acids pharmacetical