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4-Bromothiophene-2-carboxaldehyde

4-Bromothiophene-2-carboxaldehyde structure

CAS No.: 18791-75-8

Chemical Name:: 4-Bromothiophene-2-carboxaldehyde

Synonyms: 4-BROMOTHIOPHENE-2-CARBALDEHYDE;4-BROMO-2-THIOPHENECARBOXALDEHYDE;TIMTEC-BB SBB000293;4-Bromo-2-thiophene;LABOTEST-BB LT00112358;4-BROMO-2-FORMYLTHIOPHENE;3-Bromo-5-formylthiophene;4-BROMOTHIOPHENE-2-ALDEHYDE;4-Bromthiophen-2-carbaldehyd;4-BROMO-2-THIOPHENECARBALDEHYDE

CBNumber:: CB3771198

Molecular Formula:: C5H3BrOS

Molecular Weight:: 191.05

MDL Number:: MFCD00005431

MOL File:: 18791-75-8.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:47

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4-Bromothiophene-2-carboxaldehyde Properties

Melting point	44-46 °C (lit.)
Boiling point	114-115 °C/11 mmHg (lit.)
Density	1.770 (estimate)
Flash point	>230 °F
storage temp.	2-8°C
solubility	soluble in Methanol
form	Powder or Granules
color	White to beige
Sensitive	Air Sensitive
BRN	108455
InChI	InChI=1S/C5H3BrOS/c6-4-1-5(2-7)8-3-4/h1-3H
InChIKey	PDONIKHDXYHTLS-UHFFFAOYSA-N
SMILES	C1(C=O)SC=C(Br)C=1
CAS DataBase Reference	18791-75-8(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Xn,Xi

Risk Statements

36/37/38-20/21/22

Safety Statements

22-24/25-36/37/39-26-36

WGK Germany

10-23

TSCA

HazardClass

IRRITANT

HS Code

29349990

NFPA 704

	1
2		0

4-Bromothiophene-2-carboxaldehyde price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	283452	4-Bromo-2-thiophenecarboxaldehyde 90%	18791-75-8	5g	$56.3	2025-07-31	Buy
Sigma-Aldrich	283452	4-Bromo-2-thiophenecarboxaldehyde 90%	18791-75-8	25g	$186.9	2025-07-31	Buy
TCI Chemical	B2827	4-Bromothiophene-2-carboxaldehyde >98.0%(GC)	18791-75-8	5g	$41	2025-07-31	Buy
TCI Chemical	B2827	4-Bromothiophene-2-carboxaldehyde >98.0%(GC)	18791-75-8	25g	$119	2025-07-31	Buy
TRC	B688110	4-Bromo-2-thiophenecarboxaldehyde	18791-75-8	50g	$1230	2021-12-16	Buy

Product number	Packaging	Price	Buy
283452	5g	$56.3	Buy
283452	25g	$186.9	Buy
B2827	5g	$41	Buy
B2827	25g	$119	Buy
B688110	50g	$1230	Buy

4-Bromothiophene-2-carboxaldehyde Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

4-Bromo-2-thiophenecarboxaldehyde has been used:

as building block for the synthesis of tetrahydroisoquinolinones
in the synthesis of 3-[(4-bromo-2-thienyl)methylenehydrazinocarbonyl]-1H-1,2,4-triazole

Synthesis

872-31-1

68-12-2

18791-75-8

930-96-1

General procedure: a THF solution of 1 M NaHMDS (8.8 mL, 8.8 mmol) was slowly added dropwise to the substrate (6.8 mmol) at 0°C. The reaction mixture was stirred for 30 min at 0 °C, then a solution of anhydrous THF (2 mL) with electrophilic reagent (8.3 mmol) was slowly added and stirring was continued for 3 h at 0 °C. Upon completion of the reaction, the reaction was quenched with saturated NH4Cl solution (5 mL) and diluted with hexane (20 mL). The organic layer was separated and washed with 15 wt% NaCl aqueous solution (10 mL) and subsequently concentrated to give the crude product. The product was purified by fast chromatography using a silica gel column pretreated with Et3N and 0.1% Et3N/4.9% EtOAc/95% hexane as eluent.

References

[1] Tetrahedron Letters, 2012, vol. 53, # 2, p. 166 - 169
[2] Tetrahedron Letters, 2012, vol. 53, # 2, p. 166 - 169

4-Bromothiophene-2-carboxaldehyde synthesis

Synthesis of 4-Bromothiophene-2-carboxaldehyde from 2-Thiophenecarboxaldehyde

4-Bromothiophene-2-carboxaldehyde Preparation Products And Raw materials

Raw materials

2-Thiophenecarboxaldehyde Aluminum chloride Bromine Dichloromethane Thiophene, 3-bromo-2-(trimethylsilyl)-

3-Bromothiophene N,N-Dimethylformamide Ammonium chloride 2,4-Dibromothiophene 3-Bromothiophene-2-carbaldehyde

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Preparation Products

NB-598 (4-Bromo-thiophen-2-yl)-acetonitrile 4-Bromothiophene-2-carbonitrile Methyl 4-cyanothiophene-2-carboxylate 3-bromothieno[3,2-c]pyridin-4-amine

(4-BROMO-2-THIENYL)METHANOL Methyl 4-bromothiophene-2-carboxylate 4-Bromo-2-methylthiophene

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4-Bromothiophene-2-carboxaldehyde Suppliers

Global( 333)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5251	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12222	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Hebei Miaobian Biotechnology Co., Ltd	+8617733850068		CHINA	967	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
SIMAGCHEM CORP	58
Hebei Miaobian Biotechnology Co., Ltd	58

View Lastest Price from 4-Bromothiophene-2-carboxaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-23	4-Bromothiophene-2-carboxaldehyde 18791-75-8	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2025-05-26	4-Bromothiophene-2-carboxaldehyde 18791-75-8	US $9.00 / KG	1KG	99.8%	100tons	Hebei Chuanghai Biotechnology Co,.LTD
2022-03-26	4-Bromothiophene-2-carboxaldehyde 18791-75-8	US $1.10 / g	1g	99.00%	100 Tons	Dideu Industries Group Limited

4-Bromothiophene-2-carboxaldehyde
18791-75-8
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

4-Bromothiophene-2-carboxaldehyde
18791-75-8
US $9.00 / KG
99.8%
Hebei Chuanghai Biotechnology Co,.LTD

4-Bromothiophene-2-carboxaldehyde
18791-75-8
US $1.10 / g
99.00%
Dideu Industries Group Limited

4-Bromothiophene-2-carboxaldehyde Spectrum

4-Bromothiophene-2-carboxaldehyde(18791-75-8)MS 4-Bromothiophene-2-carboxaldehyde(18791-75-8)¹HNMR 4-Bromothiophene-2-carboxaldehyde(18791-75-8)¹³CNMR 4-Bromothiophene-2-carboxaldehyde(18791-75-8)IR1 4-Bromothiophene-2-carboxaldehyde(18791-75-8)IR2 4-Bromothiophene-2-carboxaldehyde(18791-75-8)Raman

18791-75-8(4-Bromothiophene-2-carboxaldehyde)Related Search:

2-Thiophenecarboxaldehyde Tetrahydrothiophene Cephalothin sodium Thifensulfuron 3-Thiophenecarboxaldehyde

Dibenzothiophene Bromine 5-BROMOTHIOPHENE-2-CARBOXALDEHYDE,2-BROMOTHIOPHENE-5-CARBOXALDEHYDE METHYL 4-BROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE 4,5-DIBROMOTHIOPHENE-2-CARBOXYLIC ACID

METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE METHYL4,5-DIBROMOTHIOPHENE-2-CARBOXYLATE 1-(4-BROMO-2-THIENYL)ETHAN-1-ONE 4,5-DIBROMOTHIOPHENE-2-CARBOXALDEHYDE 3-Bromothiophene-2-carboxaldehyde, GC 97%,3-BROMOTHIOPHENE-2-CARBOXALDEHYDE 98%,3-Bromothiophene-2-carboxaldehyde, 95%+,3-BROMOTHIOPHENE-2-CARBOXALDEHYDE

5-BROMOTHIOPHENE-2-CARBOXALDEHYDE OXIME 3-BROMOTHIOPHENE-2-CARBOXALDEHYDE DIETHYL ACETAL METHYL 4-BROMO-3-METHOXYTHIOPHENE-2-CARBOXYLATE

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4-Bromo-2-thiophenecarboxaldehyde,90% 4-BroMo-2-thiophenecarboxaldehyde, 90% 5GR 2-Thiophenecarboxaldehyde, 4-bromo- 4-Bromo-2-formylthiophene, 4-Bromo-2-thenaldehyde 4-BROMOTHIOPHENE-2-CARBALDEHYDE 4-Bromothiophene-2-carboxaldehyde 98% 4 - broMine - 2 - thiophene forMaldehyde 4-Bromothiophene-2-carboxaldehyde,96% 4-BROMOTHIOPHENE-2-CARBOXALDEHYDE 4-BROMOTHIOPHENE-2-ALDEHYDE 4-BROMO-2-THIOPHENECARBALDEHYDE 4-BROMO-2-THIOPHENECARBOXALDEHYDE 4-BROMO-2-FORMYLTHIOPHENE 4-Bromothiophen-2-carboxaldehyde TIMTEC-BB SBB000293 LABOTEST-BB LT00112358 Bromothiophene-2-carboxaldehyde 2-THIOPHENE-4-BROMOCARBOXALDEHYDE 4-Bromo-2-thiophene 4-BROMO-2-THIOPHENECARBOXALDEHYDE 90% 4-Bromothiophene-2-carboxaldehyde > 4-Bromothiophene-2-carboxaldehyde ISO 9001：2015 REACH 4-Bromthiophen-2-carbaldehyd 3-Bromo-5-formylthiophene 18791-75-8 C5H3BrOS C5H3OBrS ALDEHYDE Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Thiophenes Halogenated Heterocycles Heterocyclic Building Blocks Thiophenes ThiophenesBuilding Blocks Aldehyde Building Blocks Thiophene Aldehydes blocks Bromides Heterocycles Carbonyl Compounds Thiophene&Benzothiophene