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Erythorbic Acid

CAS No.
89-65-6
Chemical Name:
Erythorbic Acid
Synonyms
D-ISOASCORBIC ACID;(5R)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one;ISOASCORBIC ACID;ERYTHORBATE;araboascorbicacid;D-ARABOASCORBIC ACID;d-arabino-ascorbicacid;Ascorbic Acid EP Impurity F;2,3-didehydro-d-erythro-hexono-1,4-lactone;mercate5
CBNumber:
CB3777943
Molecular Formula:
C6H8O6
Molecular Weight:
176.12
MDL Number:
MFCD00005378
MOL File:
89-65-6.mol
MSDS File:
SDS
Last updated:2026-01-30 16:22:46
Product description Number Pack Size Price
D-Isoascorbic acid FG W241008 1 unit $56.3
D-Isoascorbic acid FG W241008 1 unit $56.3
D-(?)-Isoascorbic acid FG W241008 1kg $74.3
D-(?)-Isoascorbic acid FG W241008 5kg $282
AscorbicAcidImpurityF PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial PHR2418 100MG $408.5
More product size

Erythorbic Acid Properties

Melting point 169-172 °C (dec.) (lit.)
alpha -17.25 º (c=10, H2O 25 ºC)
Boiling point 227.71°C (rough estimate)
Density 1.3744 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index -17.5 ° (C=10, H2O)
FEMA 2410 | ERYTHROBIC ACID
storage temp. 2-8°C
solubility H2O: 0.1 g/mL, clear, colorless to very faintly yellow
pka 4.09±0.10(Predicted)
form Crystals or Crystalline Powder
color White to slightly yellow
Odor odorless
optical activity [α]25/D 16.8°, c = 2 in H2O
biological source (Starch)
Water Solubility 1g/10mL
Merck 14,5126
BRN 84271
Stability Stable. Combustible. Incompatible with chemically active metals, aluminium, zinc, copper, magnesium, strong bases, strong oxidizing agents.
Cosmetics Ingredients Functions ANTIOXIDANT
Cosmetic Ingredient Review (CIR) Erythorbic Acid (89-65-6)
InChI 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5-/m1/s1
InChIKey CIWBSHSKHKDKBQ-JLAZNSOCSA-N
SMILES [H][C@@]1(OC(=O)C(O)=C1O)[C@H](O)CO
LogP -1.69 at 25℃
FDA 21 CFR 182.3041; 582.3041; 175.105
CAS DataBase Reference 89-65-6(CAS DataBase Reference)
SCOGS (Select Committee on GRAS Substances) Erythorbic acid (D-isoascorbic acid)
Substances Added to Food (formerly EAFUS) ERYTHORBIC ACID
EWG's Food Scores 1
FDA UNII 311332OII1
EPA Substance Registry System Isoascorbic acid (89-65-6)
Cosmetics Info Erythorbic Acid
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-24/25
WGK Germany  2
RTECS  KF3015000
TSCA  TSCA listed
HS Code  29329990
Storage Class 11 - Combustible Solids
Hazardous Substances Data 89-65-6(Hazardous Substances Data)
NFPA 704
0
0 0

Erythorbic Acid price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W241008 D-Isoascorbic acid FG 89-65-6 1 unit $56.3 2025-07-31 Buy
Sigma-Aldrich W241008 D-Isoascorbic acid FG 89-65-6 1 unit $56.3 2025-07-31 Buy
Sigma-Aldrich W241008 D-(?)-Isoascorbic acid FG 89-65-6 1kg $74.3 2025-07-31 Buy
Sigma-Aldrich W241008 D-(?)-Isoascorbic acid FG 89-65-6 5kg $282 2025-07-31 Buy
Sigma-Aldrich PHR2418 AscorbicAcidImpurityF PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial 89-65-6 100MG $408.5 2025-07-31 Buy
Product number Packaging Price Buy
W241008 1 unit $56.3 Buy
W241008 1 unit $56.3 Buy
W241008 1kg $74.3 Buy
W241008 5kg $282 Buy
PHR2418 100MG $408.5 Buy

Erythorbic Acid Chemical Properties,Uses,Production

Odor

Practically odorless. Clean acidulous taste, resembling that of Citric acid, but somewhat milder.

Chemical Properties

Erythorbic acid occurs as a white or slightly yellow-colored crystals or powder. It gradually darkens in color upon exposure to light.

Uses

Antioxidant (industrial and food), especially in brewing industry, reducing agent in photography.

Uses

Erythorbic Acid is a food preservative that is a strong reducing agent (oxygen accepting) which functions similarly to antioxidants. In the dry crystalline state it is nonreactive, but in water solutions it reacts readily with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant. During preparation, dissolving and mixing should incorporate a minimum amount of air, and storage should be at cool temperatures. It has a solubility of 43 g/100 ml of water at 25°c. One part is equivalent to one part ascorbic acid and equivalent to one part sodium erythorbate. It is used to control oxidative color and flavor deterioration in fruits at 150–200 ppm. It is used in meat curing to speed and control the nitrite curing reaction and prolong the color of cured meat at levels of 0.05%.

Uses

Erythorbic Acid is used as a food additive as an antimicrobial and antioxidative agent.

Definition

ChEBI: D-isoascorbic acid is an ascorbic acid.

Production Methods

Erythorbic acid is synthesized by the reaction between methyl 2- keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose, and produced from Penicillium spp.

Biotechnological Production

Yeasts and other fungi synthesize the C5 sugar acid D-erythroascorbic acid which shares structural and physicochemical properties with Asc. D-erythroascorbic acid serves similar protective functions in these microorganisms as Asc does in plants and animals, including the scavenging of reactive oxygen species. The biosynthesis of D-erythroascorbic acid starts from D-arabinose obtained by the microorganism from decaying plant material. D-arabinose, presumably in its 1,4-furanosidic isomeric form, is oxidized by NAD(P)+ specific dehydrogenases to D-arabinono-1,4-lactone, which is further oxidized to D-erythroascorbic acid by D-arabinono-1,4-lactone oxidase. Resting cells of Saccharomyces cerevisiae can synthesize Asc from L-galactose, L-galactono-1,4-lactone, or L-gulono- 1,4-lactone via the pathway naturally used for D-erythroascorbic acid.

Flammability and Explosibility

Non flammable

Pharmaceutical Applications

Erythorbic acid is a stereoisomer of L-ascorbic acid, and is used as an antioxidant in foods and oral pharmaceutical formulations. It has approximately 5% of the vitamin C activity of L-ascorbic acid.

Safety

Erythorbic acid is widely used in food applications as an antioxidant. It is also used in oral pharmaceutical applications as an antioxidant. Erythorbic acid is generally regarded as nontoxic and nonirritant when used as an excipient. Erythorbic acid is readily metabolized and does not affect the urinary excretion of ascorbic acid.
The WHO has set an acceptable daily intake of erythorbic acid and its sodium salt in foods at up to 5 mg/kg body-weight.

Solubility in organics

40% soluble in water. Soluble in alcohol, slightly soluble in Glycerin and Propylene glycol.

storage

Erythorbic acid should be stored in an airtight container, protected from light, in a cool, dry place.

Purification Methods

Crystallise D(-)-isoascorbic acid from H2O, EtOH or dioxane. is at 245nm with 7,500 (EtOH). [Reichstein et al. Helv max Chim Acta 17 510, 516 1934, Heslop et al. J Chem Soc 225 1944, Beilstein 18 III/IV 3037, 18/5 V 26.]

Incompatibilities

Erythorbic acid is incompatible with chemically active metals such as aluminum, copper, magnesium, and zinc. It is also incompatible with strong bases and strong oxidizing agents.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral concentrate and tablets).

7647-01-0
669-90-9
7732-18-5
89-65-6
Synthesis of Erythorbic Acid from Hydrochloric acid and 2-oxogluconic acid and Water
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View Lastest Price from Erythorbic Acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Erythorbic Acid pictures 2026-02-03 Erythorbic Acid
89-65-6
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
Erythorbic Acid pictures 2026-02-02 Erythorbic Acid
89-65-6
US $9.90-99.00 / Kg 1Kg 98% 3000MT Xinxiang Aurora Biotechnology Co.,Ltd.
Erythorbic Acid pictures 2026-01-30 Erythorbic Acid
89-65-6
US $0.00 / removed 99.80% 10g TargetMol Chemicals Inc.
  • Erythorbic Acid pictures
  • Erythorbic Acid
    89-65-6
  • US $9.90-99.00 / Kg
  • 98%
  • Xinxiang Aurora Biotechnology Co.,Ltd.
2,3-didehydro-d-erythro-hexono-1,4-lactone FEMA 2410 ISOASCORBIC ACID ISOVITAMIN C 3-keto-d-erythro-hexonicacigamma-lactone araboascorbicacid d-arabino-ascorbicacid d-erythro-3-ketohexonicacidlactone D-Erythro-3-ketohex-onicacidlactone d-erythro-3-oxohexonicacidlactone d-erythro-ascorbicacid erythro-Hex-2-enonicacid,1,4-lactone femanumber:2410 glucosaccharonicacid mercate"5" mercate5 D-(-)-ARABOASCORBIC ACID D-ARABOASCORBIC ACID D-ERYTHRO-3-KETOHEXANOIC ACIDLACTONE D-ERYTHRO-3-OXOHEXANOIC ACID LACTONE D-Erythro-hex-2-enonic acid D-ERYTHRO-HEX-2-ENONIC ACID, GAMMA-LACTONE D-(-)-ERYTHORBIC ACID D-ERYTHORBIC ACID ERYCORBIN ERYTHORBIC ACID D(-)-ISOASCORBIC ACID D-ISOASCORBIC ACID (2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one SACCHAROSONIC ACID NEOCEBICURE D-erythro-Hex-2-enoic acid γ-lactone D-ISOASCORBIC ACID 99+% FCC D-IsoascorbicAcid,>99% ERYTHORBICACID,FCC D-(-)-ARABOASCORBICACID(ERYTHORBICACID) Araboascorbic acid, D- D-erythro-Hex-2-enonic acid, γ-lactone (8CI, 9CI) D-erythro-Hexonic acid, 3-keto-, γ-lactone (6CI) D-erythro-Hex-2-enoic acid γ-lactone D-Araboascorbic acid D-Erythorbic Acid Ascorbic Acid Impurity 6(Ascorbic Acid EP Impurity F) sodium 5-(1,2-dihydroxyethyl)-3-hydroxyfuran-3-ide-2,4-dione Ascorbic Acid EP Impurity F Powder Erythorbic Acid FCC4 D(-)-Isoascorbic Acid (Erythorbic Acid) Erythorbic acid (7CI) NSC 8117 D-ASCORBICACID ERYTHORBATE D-erythro-Hex-2-enoic acid γ-lactone, D-Araboascorbic acid D-(-)-Isoascorbic acid, D-erythro-Hex-2-enoic acid γ-lactone, D-Araboascorbic acid, Erythorbic acid (R)-5-[(R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one 3,4-Dihydroxy-5β-[(R)-1,2-dihydroxyethyl]-2(5H)-furanone D(-)-Isoascorbic acid,98% D-()-Isoascorbic acid,D-erythro-Hex-2-enoic acid γ-lactone, D-Araboascorbic acid D-Isoascorbic acid,D-()-Isoascorbic acid, D-erythro-Hex-2-enoic acid γ-lactone, D-Araboascorbic acid, Erythorbic acid )-Isoascor Erythorbic Acid (50 mg)