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2-PYRAZOL-1-YL-PYRIDINE

2-PYRAZOL-1-YL-PYRIDINE Structure
2-PYRAZOL-1-YL-PYRIDINE structure
CAS No.
25700-11-2
Chemical Name:
2-PYRAZOL-1-YL-PYRIDINE
Synonyms
2-pyrazole-1-pyridine;2-(1-Pyrazolyl)pyridine;2-PYRAZOL-1-YL-PYRIDINE;2-(1-Pyrazolyl)pyridine >2-(1H-pyrazol-1-yl)pyridine;Pyridine, 2-(1H-pyrazol-1-yl)-
CBNumber:
CB3840494
Molecular Formula:
C8H7N3
Molecular Weight:
145.16
MDL Number:
MFCD09033534
MOL File:
25700-11-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:17
Product description Number Pack Size Price
2-(1-Pyrazolyl)pyridine >98.0%(GC) P2239 1g $73
2-(1-Pyrazolyl)pyridine >98.0%(GC) P2239 5g $231
2-PYRAZOL-1-YL-PYRIDINE 97% 65480 1G $41
2-(1H-Pyrazol-1-yl)pyridine B529850 10mg $45
2-(1H-Pyrazol-1-yl)pyridine 8520AD 1g $117
More product size
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2-PYRAZOL-1-YL-PYRIDINE Properties

Melting point 37.0 to 41.0 °C
Boiling point 265.6±13.0 °C(Predicted)
Density 1.16±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
pka 2.83±0.10(Predicted)
form powder to lump
color White to Almost white
InChIKey XXTPHXNBKRVYJI-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
HS Code  2933399990
NFPA 704
0
1 0

2-PYRAZOL-1-YL-PYRIDINE price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical P2239 2-(1-Pyrazolyl)pyridine >98.0%(GC) 25700-11-2 1g $73 2026-04-30 Buy
TCI Chemical P2239 2-(1-Pyrazolyl)pyridine >98.0%(GC) 25700-11-2 5g $231 2026-04-30 Buy
AstaTech 65480 2-PYRAZOL-1-YL-PYRIDINE 97% 25700-11-2 1G $41 2026-04-30 Buy
TRC B529850 2-(1H-Pyrazol-1-yl)pyridine 25700-11-2 10mg $45 2021-12-16 Buy
AK Scientific 8520AD 2-(1H-Pyrazol-1-yl)pyridine 25700-11-2 1g $117 2021-12-16 Buy
Product number Packaging Price Buy
P2239 1g $73 Buy
P2239 5g $231 Buy
65480 1G $41 Buy
B529850 10mg $45 Buy
8520AD 1g $117 Buy

2-PYRAZOL-1-YL-PYRIDINE Chemical Properties,Uses,Production

Synthesis

Pyrazole

288-13-1

2-Bromopyridine

109-04-6

2-PYRAZOL-1-YL-PYRIDINE

25700-11-2

General procedure for the synthesis of 2-pyrazole-1-pyridine (Pyr-N-PzH) from pyrazole and 2-bromopyridine: To a 250 mL single-necked round-bottomed flask were added 15.0 g (95 mmol) of 2-bromopyridine, 25.0 g (367 mmol, 3.86 equiv) of pyrazole and 45 mL of xylene. The reaction mixture was heated to reflux for 8 hours and subsequently cooled to room temperature. The resulting mixture was dissolved in dichloromethane and the organic layer was washed four times with 250 mL of water (until pyrazole was not detected by gas chromatography). The organic layer was dried over anhydrous magnesium sulfate, filtered and rotary evaporated to give 12.0 g (82.6 mmol, 87% yield) of the target product as a white solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 8.59 (m, 1H, pyridinyl 6-H), 8.39 (s, 1H, pyrazol-5-H), 7.90 (d, 1H, pyridinyl 3-H), 7.80 (m, 1H, pyridinyl 4-H), 7.73 (s, 1H, pyrazol 3-H), 7.15 (s, 1H, pyridinyl -5-H), 6.45 (m, 1H, pyrazole-4-H).

References

[1] Tetrahedron, 2010, vol. 66, # 47, p. 9141 - 9144
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 13, p. 4101 - 4114
[3] European Journal of Organic Chemistry, 2011, # 14, p. 2692 - 2696
[4] Journal of Organic Chemistry, 2005, vol. 70, # 13, p. 5164 - 5173
[5] Journal of Organic Chemistry, 2011, vol. 76, # 2, p. 654 - 660

2-PYRAZOL-1-YL-PYRIDINE synthesis

288-13-1
1120-90-7
25700-11-2
Synthesis of 2-PYRAZOL-1-YL-PYRIDINE from Pyrazole and 3-Iodopyridine

2-PYRAZOL-1-YL-PYRIDINE Preparation Products And Raw materials

Raw materials

2-Iodopyridine 3-Iodopyridine 1,1,3,3-Tetramethoxypropane 2-Chloropyridine 2-Bromopyridine
Pyrazole 2-Hydrazinopyridine 2-Aminopyridine

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Preparation Products

2-PYRAZOL-1-YL-PYRIDINE Suppliers

Global( 78)Suppliers
Supplier Tel Email Country ProdList Advantage
Springchem New Material Technology Co.,Limited 		+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30227 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24529 81
Nanjing Norris-Pharm Technology Co., Ltd 18652989687 sales@norris-pharm.com China 8878 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28387 80
Supplier Advantage
Springchem New Material Technology Co.,Limited 		57
ATK CHEMICAL COMPANY LIMITED 		60
Career Henan Chemica Co 		58
Hefei Hirisun Pharmatech Co., Ltd 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
TCI (Shanghai) Development Co., Ltd. 81
Nanjing Norris-Pharm Technology Co., Ltd 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 80

2-PYRAZOL-1-YL-PYRIDINE Spectrum

2-PYRAZOL-1-YL-PYRIDINE(25700-11-2)1HNMR

25700-11-2(2-PYRAZOL-1-YL-PYRIDINE)Related Search:

6-(1H-Pyrazol-1-yl)nicotinic acid Methyl 6-(1H-pyrazol-1-yl)pyridine-3-carboxylate 5-amino-1-(pyridin-2-yl)-1H-pyrazole-4-carbonitrile 1-(6-FLUORO-2-PYRIDINYL)-4-PHENYL-1H-PYRAZOL-3-AMINE N-(4-METHOXYPHENYL)-6-(1H-PYRAZOL-1-YL)NICOTINAMIDE
N-(3-METHOXYPHENYL)-6-(1H-PYRAZOL-1-YL)NICOTINAMIDE 1-(6-CHLORO-2-PYRIDINYL)-N-METHYL-4-NITRO-1H-PYRAZOL-5-AMINE 1-[5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-YL]-4-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE 7-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-2,4-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDINE 1-[5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-YL]-4-(4-METHOXYPHENYL)-1H-PYRAZOL-5-AMINE
1-[5-methyl-1-(pyridin-2-yl)-1H-pyrazol-4-yl]ethan-1-one N-METHYL-4-NITRO-1-(2-PYRIDINYL)-1H-PYRAZOL-5-AMINE 1-[5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-YL]-4-PHENYL-1H-PYRAZOL-5-AMINE 1-[5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-YL]-4-(4-FLUOROPHENYL)-1H-PYRAZOL-5-AMINE N-(2-METHOXYPHENYL)-6-(1H-PYRAZOL-1-YL)NICOTINAMIDE
2-FLUORO-6-(3-PHENYL-1H-PYRAZOL-1-YL)PYRIDINE N-(2,5-DIMETHOXYPHENYL)-6-(1H-PYRAZOL-1-YL)NICOTINAMIDE 2-FLUORO-6-[3-(4-METHOXYPHENYL)-1H-PYRAZOL-1-YL]PYRIDINE

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2-PYRAZOL-1-YL-PYRIDINE 2-(1H-pyrazol-1-yl)pyridine 2-(1-Pyrazolyl)pyridine 2-(1-Pyrazolyl)pyridine > Pyridine, 2-(1H-pyrazol-1-yl)- 2-pyrazole-1-pyridine 25700-11-2