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3-Trifluoromethyl-1H-indole

CAS No.
51310-55-5
Chemical Name:
3-Trifluoromethyl-1H-indole
Synonyms
3-Trifluoromethyl-1H-indole;1H-Indole, 3-(trifluoroMethyl)-
CBNumber:
CB3849664
Molecular Formula:
C9H6F3N
Molecular Weight:
185.15
MDL Number:
MFCD09032290
MOL File:
51310-55-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:13

3-Trifluoromethyl-1H-indole Properties

Melting point 109-110 °C
Boiling point 256.7±35.0 °C(Predicted)
Density 1.367±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 15.16±0.30(Predicted)
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933998090

3-Trifluoromethyl-1H-indole price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0008617 3-(Trifluoromethyl)-1H-indole ≥97% 51310-55-5 50mg $92 2026-06-04 Buy
ChemScene CS-0008617 3-(Trifluoromethyl)-1H-indole ≥97% 51310-55-5 100mg $120 2026-06-04 Buy
Apolloscientific PC421143 3-(Trifluoromethyl)-1h-indole 95% 51310-55-5 50mg $116 2026-06-04 Buy
ChemScene CS-0008617 3-(Trifluoromethyl)-1H-indole ≥97% 51310-55-5 250mg $196 2026-06-04 Buy
Apolloscientific PC421143 3-(Trifluoromethyl)-1h-indole 95% 51310-55-5 100mg $153 2026-06-04 Buy
Product number Packaging Price Buy
CS-0008617 50mg $92 Buy
CS-0008617 100mg $120 Buy
PC421143 50mg $116 Buy
CS-0008617 250mg $196 Buy
PC421143 100mg $153 Buy

3-Trifluoromethyl-1H-indole Chemical Properties, Uses, Production

Synthesis

Indole

120-72-9

Sodium trifluoromethanesulfinate

2926-29-6

2-Trifluoromethylindole

51310-54-4

3-TRIFLUOROMETHYL-1H-INDOLE

51310-55-5

GENERAL METHODS: Indole derivative (0.3 mmol, 1.0 eq.), sodium trifluoromethanesulfinate (0.6 mmol, 2.0 eq.), 2-tert-butyl anthraquinone (0.06 mmol, 0.2 eq.), and ammonium carbonate (0.18 mmol, 0.6 eq.) were sequentially added to a quartz reaction tube. Hexafluoroisopropanol (0.075 mmol, 0.25 eq.) and acetonitrile (3 mL, 0.1 M) were subsequently added as solvents. The reaction mixture was exposed to 255 nm UV light for 24 hours. Upon completion of the reaction, the reaction was quenched with water and extracted with dichloromethane or ethyl acetate (3 x 30 mL). The organic phases were combined, dried with anhydrous sodium sulfate, and concentrated under reduced pressure to remove the solvent. Finally, the target products 2-trifluoromethylindole and 3-(trifluoromethyl)-1H-indole were obtained by preparative thin-layer chromatography (TLC) using a suitable solvent system.

References

[1] Journal of Fluorine Chemistry, 2018, vol. 214, p. 94 - 100

3-Trifluoromethyl-1H-indole Preparation Products And Raw materials

3-Trifluoromethyl-1H-indole Suppliers

Global Suppliers ( 36)
Supplier Tel Email Country ProdList Advantage
Shanghai Targsense Scientific Co., Ltd. 18916626092 targsense@qq.com China 110 65
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
SynAsst Chemical. 021-60343070 China 12731 55
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 3014 58
Chengdu 3S Pharmaceutical Technology Co., Ltd. 028-62577698; 19950139520 cd_chemical@126.com China 292 56
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15775 55
Hangzhou J&H Chemical Co., Ltd. 0571-87396432 sales@jhechem.com China 14905 59
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 6746 58
Aikon International Limited 025-58859352 15955137747 sales01@aikonchem.com China 16021 58

3-Trifluoromethyl-1H-indole Spectrum

1H-Indole, 3-(trifluoroMethyl)- 3-Trifluoromethyl-1H-indole 51310-55-5