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Eletriptan hydrobromide

CAS No.
177834-92-3
Chemical Name:
Eletriptan hydrobromide
Synonyms
Relert;Uk 116044-04;Eletriptan HCl;ELETRIPTAN HBR;Eletriptan Base;Unii-m41W832ta3;Eletriptan-d3 HBr;QR-2008082103-ELCPT;etriptan hydrobromide;eletriptan hydrobromide
CBNumber:
CB3854925
Molecular Formula:
C22H27BrN2O2S
Molecular Weight:
463.43
MDL Number:
MFCD18642857
MOL File:
177834-92-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:21:52
Product description Number Pack Size Price
Eletriptan hydrobromide ≥98% (HPLC) SML3032 10MG $104
Eletriptan hydrobromide ≥98% (HPLC) SML3032 50MG $338
Eletriptan Hydrobromide United States Pharmacopeia (USP) Reference Standard 1234453 200MG $725
Eletriptan hydrobromide 99% Axon2050 10mg $99
Eletriptan hydrobromide 99% Axon2050 50mg $264
More product size

Eletriptan hydrobromide Properties

Melting point 169-171C
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO: >10mg/mL
form powder
color off-white to light tan
InChIKey PWVXXGRKLHYWKM-IBGZPJMESA-N
SMILES C([C@H]1CCCN1C)C1=CNC2C=CC(CCS(C3C=CC=CC=3)(=O)=O)=CC1=2.Br |&1:1,r|
FDA UNII M41W832TA3
UNSPSC Code 41116107
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H318-H412
Precautionary statements  P264-P270-P273-P280-P301+P312-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
WGK Germany  3
HS Code  29339900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Chronic 3
Eye Dam. 1

Eletriptan hydrobromide price More Price(82)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML3032 Eletriptan hydrobromide ≥98% (HPLC) 177834-92-3 10MG $104 2026-04-30 Buy
Sigma-Aldrich SML3032 Eletriptan hydrobromide ≥98% (HPLC) 177834-92-3 50MG $338 2026-04-30 Buy
Sigma-Aldrich 1234453 Eletriptan Hydrobromide United States Pharmacopeia (USP) Reference Standard 177834-92-3 200MG $725 2026-04-30 Buy
Axon Medchem Axon2050 Eletriptan hydrobromide 99% 177834-92-3 10mg $99 2026-05-19 Buy
Axon Medchem Axon2050 Eletriptan hydrobromide 99% 177834-92-3 50mg $264 2026-05-19 Buy
Product number Packaging Price Buy
SML3032 10MG $104 Buy
SML3032 50MG $338 Buy
1234453 200MG $725 Buy
Axon2050 10mg $99 Buy
Axon2050 50mg $264 Buy

Eletriptan hydrobromide Chemical Properties,Uses,Production

Chemical Properties

Eletriptan hydrobromide is Tan Solid

Originator

Relpax,Pfizer

Uses

Relpax is a second generation triptan drug used in the treatment of migraine headaches.

Uses

antibiotic

Uses

Eletriptan hydrobromide is a second generation triptan drug used in the treatment of migraine headaches.

Definition

ChEBI: Eletriptan hydrobromide is a hydrobromide. It has a role as a serotonergic agonist, a vasoconstrictor agent and a non-steroidal anti-inflammatory drug. It contains an eletriptan(1+).

Manufacturing Process

A mixture of the appropriate phenyl vinyl sulfone, tri-o-tolylphosphine, palladium (II) acetate, triethlamine and (R)-5-bromo-3-(Nmethylpyrrolidinylmethyl)-1H-indole in anhydrous acetonitrle was heated at reflux under nitrogen. The resultant reaction mixture was evaporated under reduced pressure, and the residue was column chromatographed using silica gel and elution with methylene chloride/absolute ethanol/ammonia to afford the (R )-5-trans-(2-phenylsulfonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)- 1H-indole.
A solution of (R)-5-trans-(2-phenylsulfonylethenyl)-3-(N-methylpyrrolidin-2- ylmethyl)-1H-indole and 10% Pd/C in ethanolic hydrogen chloride (prepared from absolute ethanol and acetyl chloride and N,N-dimethylformamide was shaken under a hydrogen atmosphere at room temperature). The resultant reaction mixture was filtered through diatomaceous earth (Celite trademark), washed with absolute ethanol, and the combined filtrates were evaporated under reduced pressure. The residue was partitioned between ethyl acetate and water. The organic phase was separated, washed with water, brine, dried(Na2SO4), and evaporated under reduced pressure to afford a oil product. Column chromatography of this product using silica gel and elution with methylene chloride/absolute ethanol/ammonia afforded the appropriate (R)-5- (2-phenylsulfonylethyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole.
The salt eletriptan hydrobromide may be produced by reaction of the (R)-5- (2-phenylsulfonylethyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole with hydrobromic acid.

brand name

Relpax (Pfizer).

Therapeutic Function

Serotonin agonist

Biological Activity

Orally active, selective 5-HT 1B/1D receptor agonist. Produces a dose-dependent reduction in carotid artery blood flow in vivo . Displays antimigraine activity.

storage

room temperature (desiccate)

143322-58-1
177834-92-3
Synthesis of Eletriptan hydrobromide from Eletriptan
Global( 222)Suppliers
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Henan Tianfu Chemical Co.,Ltd.
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Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
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TargetMol Chemicals Inc.
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Win-Win chemical CO., Limited
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
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Shanxi Xuanran Import and Export Trade Co., Ltd.
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View Lastest Price from Eletriptan hydrobromide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Eletriptan hydrobromide pictures 2026-05-27 Eletriptan hydrobromide
177834-92-3
US $52.00-136.00 / mg 99.69% 10g TargetMol Chemicals Inc.
Eletriptan hydrobromide pictures 2026-05-27 Eletriptan hydrobromide
177834-92-3
US $52.00-136.00 / mg 99.69% 10g TargetMol Chemicals Inc.
Eletriptan hydrobromide pictures 2026-05-27 Eletriptan hydrobromide
177834-92-3
US $52.00-136.00 / mg 99.69% 10g TargetMol Chemicals Inc.

Eletriptan hydrobromide Spectrum

Unii-m41W832ta3 Relpax Also see: E505000 Eletriptan HCl 1H-Indole,3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-,hydrobromide (R)-5-[2-(Benzenesulfonyl)ethyl]-3-[(N-Methylpyrrolidin-2-yl)Methyl]-1H-indole hydrobroMide Relert (R)-3-((1-Methylpyrrolidin-2-yl)Methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole hydrobroMide eletriptan hydrobromide 3-(((2r)-1-methyl-2-pyrrolidinyl))methyl)-5-(2-(phenylsulfonyl)ethyl)-1h-indole hydrobromide ELETRIPTAN HBR Eletriptan Base 1H-Indole, 3-(((2R)-1-methyl-2-pyrrolidinyl))methyl)-5-(2-(phenylsulfonyl)ethyl)-, monohydrobromide Uk 116044-04 Eletriptan hydrobromide (Eletriptan HBr) Eletriptan hydrobromide, 99%, a selective 5-HT1B/1D receptor agonist 5-[2-(benzenesulfonyl)ethyl]-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indole hydrobromide Eletriptan-d3 HBr etriptan hydrobromide Eletriptan hydrobromide USP/EP/BP QR-2008082103-ELCPT Eletriptan Related compound 01 Eletriptan HydrobromideQ: What is Eletriptan Hydrobromide Q: What is the CAS Number of Eletriptan Hydrobromide Q: What is the storage condition of Eletriptan Hydrobromide Q: What are the applications of Eletriptan Hydrobromide 177834-92-3 Eletriptan hydrobromide 1H-Indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-, hydrobromide (1:1) (R)-5-(2-Benzenesulfonyl -ethyl)-3-(1- methyl- pyrrolidin-2- ylmethyl)-1H- indole. Hydrobromide Eletriptan hydrobromide, 10 mM in DMSO ELETRIPTAN HYDROBROMIDE (PROCESS 1) Eletriptan HBr - Bio-X ? 177834-92-3 C22H26N2O2SHBr C22H26N2O2SBrH C22H27BrN2O2S Aromatics Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pfizer compounds Pharmaceuticals