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ChemicalBook >> CAS DataBase List >>N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea

N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea

N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea Structure
N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea structure
CAS No.
52378-40-2
Chemical Name:
N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea
Synonyms
Einecs 257-889-5;Cimetidine EP IMP A;Cimetidine impurity A;Cimetidine EP Impurity A;Cimetidine Impurity A(EP);3-Cyano-2-methyl-1-[2-[[(5-methyl-1;Cimetidine Hydrochloride Impurity A;Cimetidine Hydrochloride EP Impurity A;Cimetidine Impurity 1（Cimetidine EP Impurity A）;N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl...
CBNumber:
CB3875377
Molecular Formula:
C10H15N5S2
Molecular Weight:
269.39
MDL Number:
MFCD09751289
MOL File:
52378-40-2.mol
Last updated:2026-05-28 01:16:13
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N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea Properties

Melting point 148-150℃
Boiling point 501.5±60.0 °C(Predicted)
Density 1.29±0.1 g/cm3(Predicted)
storage temp. Amber Vial, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 14.11±0.10(Predicted)
color Yellow
Stability Light Sensitive
Major Application pharmaceutical
InChI 1S/C10H15N5S2/c1-8-9(15-7-14-8)5-17-4-3-12-10(16-2)13-6-11/h7H,3-5H2,1-2H3,(H,12,13)(H,14,15)
InChIKey WSUNDBVVUCLXTG-UHFFFAOYSA-N
SMILES S(CCN=C(SC)NC#N)Cc1[nH]cnc1C
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Warning
Hazard statements  H334-H302+H312+H332-H317
Precautionary statements  P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
REACH Registrations Active

N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2220 Cimetidine Impurity A Pharmaceutical Secondary Standard; Certified Reference Material 52378-40-2 100mg $464 2026-04-30 Buy
Usbiological 458515 Cimetidine EP Impurity A ≥97% 52378-40-2 50mg $329 2026-06-03 Buy
Usbiological 458515 Cimetidine EP Impurity A ≥97% 52378-40-2 100mg $463 2026-06-03 Buy
Usbiological 458515 Cimetidine EP Impurity A ≥97% 52378-40-2 250mg $655 2026-06-03 Buy
TRC TRC-C981850-25MG N-Cyano-N’-[2-[(4-methyl-5-imidazolyl)methylthio]ethyl]-S-methylisothiourea >95%(HPLC) 52378-40-2 25mg $201 2026-06-03 Buy
Product number Packaging Price Buy
PHR2220 100mg $464 Buy
458515 50mg $329 Buy
458515 100mg $463 Buy
458515 250mg $655 Buy
TRC-C981850-25MG 25mg $201 Buy

N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea Chemical Properties, Uses, Production

Uses

N-Cyano-N’-[2-[(4-methyl-5-imidazolyl)methylthio]ethyl]-S-methylisothiourea (Cimetidine EP Impurity A) is a Cimetidine (C441650) related impurity. Cimetidine (C441650), a competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output. Also used in the preparation of histamine H2 receptor antagonists.

N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea Preparation Products And Raw materials

Raw materials

Preparation Products

N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea Suppliers

Global Suppliers ( 97)
Supplier Tel Email Country ProdList Advantage
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 5000 50
Zhengzhou ALFA Chemical Co., Ltd. 0371-53732842 15981811963 1758257485@qq.com China 949 56
Shandong Boluoda Biological Technology Co., Ltd. 0531-68651502 2310993908@qq.com China 3228 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4777 55
Hubei widely chemical technology Co., Ltd. 027-83991130 18627774460 1718093273@QQ.COM China 1617 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Guangzhou Kafen Biotech Co.,Ltd 18029243487 2355327168 gy@yccreate.com China 4738 55
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9995 55
Supplier Advantage
S.Z. PhyStandard Bio-Tech. Co., Ltd. 50
Zhengzhou ALFA Chemical Co., Ltd. 56
Shandong Boluoda Biological Technology Co., Ltd. 58
Shanghai Kewel Chemical Co., Ltd. 50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 50
Nanjing XiZe Biotechnology CO., Ltd. 55
Hubei widely chemical technology Co., Ltd. 58
Amadis Chemical Company Limited 58
Guangzhou Kafen Biotech Co.,Ltd 55
Hubei Yangxin Medical Technology Co., Ltd. 55

View Latest Price from N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea pictures 2025-06-20 N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea
52378-40-2
 1kg 99% 20tons Hebei Yanxi Chemical Co., Ltd.

52378-40-2 (N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea) Related Search:

4-[[(2-aminoethyl)thio]methyl]-5-methylimidazole guanylurea cimetidine Cimetidine Impurity 3 Cimetidine Impurity 2 Cimetidine Impurity 12
N-cyano-N',N''-dimethylguanidine N-Cyano-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]carbamimidic acid methyl ester 2-cyano-1,3-bis(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine N-Cyano-3-(cyanoaMino)-N'-Methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-iMidaMide (CiMetidine IMpurity) Cimetidine Amide Dihydrochloride
2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethylamine dihydrochloride (5-Ethyl-1H-imidazol-4-yl)methanol Cimetidine Tinidazole Cimetidine sulphoxide dihydrochloride
N-Cyano-N',N'-dimethylguanidine Cimetidine dihydrochloride imp D Dimethylcyanamide

1of4

N-Cyano-S-methyl-N''-[2-(4-methyl-5-imidazolyl)-methylthioethyl]- isothioure 2-Methyl-1-cyano-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]isothiourea N1-[2-[(5-Methyl-1H-imidazole-4-yl)methylthio]ethyl]-N2-cyano(methylthio)methanamidine Einecs 257-889-5 N-Cyano-N-[2-(5-MethyliMidazole-4-Methylthio)ethyl]-S-Methyl isothiourea Monohydrate N-Cyano-N'-[2-[(4-methyl-5-imidazolyl)methylthio]ethyl]-S-methylisothiourea N-Cyano-N'-[2-[[(5-methyl-4-imidazolyl)methyl]thio]ethyl]-S-methylisothiourea S-Methyl-N-cyano-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]isothiourea N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea 1-cyano-2-methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]isothiourea 1-CYANO-2-METHYL-1-[2-(5-METHYLIMIDAZOL-4-YL-METHYLTHIO)ETHYL]ISO-THIO UREA N-CYANO-N(2-((5-METHYL-1H-IMIDAZOL-4-YL)METHYL)THYL)THIO)ETHYL)CARBAMIMIDOTHIOIC ACID METHYL ESTER N-Cyano-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]carbamimidothioic acid methyl ester N-Cyano-N'-2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl-S-methylisothiourea 3-CYANO-2-METHYL-1-[2-[[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]SULPHANYL]ETHYL]ISOTHIOUREA Cimetidine impurity A Cimetidine EP Impurity A Cimetidine Impurity A(EP) Cimetidine Impurity 1（Cimetidine EP Impurity A） Cimetidine EP IMP A Carbamimidothioic acid,N-cyano-N'-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-, methyl ester Cimetidine impurity 1/Cimetidine EP Impurity A/Cimetidine Methylsulfanyl Analog /Methyl 3-cyano-1-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl]ethyl] carbamimidothioate 3-Cyano-2-methyl-1-[2-[[(5-methyl-1 (E)-methyl N'-cyano-N-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)carbamimidothioate methyl N-cyano-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]carbamimidothioate N-Cyano-N'-[2-(4-methyl-5-imidazolyl)methylthio]etheyl -S-methylisothiourea N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl... Cimetidine EP Impurity AQ: What is Cimetidine EP Impurity A Q: What is the CAS Number of Cimetidine EP Impurity A Q: What is the storage condition of Cimetidine EP Impurity A Q: What are the applications of Cimetidine EP Impurity A Methyl 3-cyano-1-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl]ethyl] carbamimidothioate Cimetidine Hydrochloride Impurity A Cimetidine Hydrochloride EP Impurity A methyl N'-cyano-N-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)carbamimidothioate N-Cyano-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-,Carbamimidothioic acid methyl ester (Cimetidine Impurity) N-Cyano-N’-[2-[(4-methyl-5-imidazolyl)methylthio]ethyl]-S-methylisothiourea 52378-40-2 C10H15N5S2 C10H15N6S2H2O