tibric acid
- CAS No.
- 37087-94-8
- Chemical Name:
- tibric acid
- Synonyms
- Tibric;CP-18524;tibric acid;2-Chloro-5-[(3α,5α-dimethylpiperidino)sulfonyl]benzoic acid;2-Chloro-5-[[(3S,5R)-3,5-dimethylpiperidino]sulfonyl]benzoic acid;2-Chloro-5-[[(3R,5S)-3,5-dimethylpiperidino]sulfonyl]benzoic acid
- CBNumber:
- CB3879698
- Molecular Formula:
- C14H18ClNO4S
- Molecular Weight:
- 331.818
- MDL Number:
- MFCD00865752
- MOL File:
- 37087-94-8.mol
| form | Solid |
|---|---|
| color | White to off-white |
| FDA UNII | LK312SQ24Z |
tibric acid Chemical Properties,Uses,Production
Uses
Tibric acid (CP 18524) has similar effects to those of hypolipidemic agents. Tibric acid has orally active triglyceride-lowering effects. Tibric acid can be used for research of hypertriglyceridemia[1][2].
in vivo
Tibric acid (13-125 mg/kg/d, oral administration, daily for 1 week) reduces serum cholesterol and triglyceride levels in rats[2].
| Animal Model: | Rats[1] |
| Dosage: | 13, 25, 125 mg/kg/d |
| Administration: | oral administration, daily for 1 week |
| Result: | Decreased serum cholesterol and triglyceride levels, but increased total liver content of cholesterol, phospholipids, and triglycerides. |
References
[1] Bielmann P, et al. Dose-response to tibric acid: a new hypolipidemic drug in type IV hyperlipoproteinemia. Clin Pharmacol Ther. 1975 May;17(5):606-11. DOI:10.1002/cpt1975175606
[2] Cayen MN, et al. Effect of tibric acid on hepatic cholesterol synthesis in rats. Lipids. 1977 Aug;12(8):684-8. DOI:10.1007/BF02533766
tibric acid Preparation Products And Raw materials
Raw materials
Preparation Products
tibric acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19905 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19965 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | 58 |
| TargetMol Chemicals Inc. | 58 |
View Lastest Price from tibric acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | Tibric acid
37087-94-8
|
US $1520.00-2500.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Tibric acid
37087-94-8
- US $1520.00-2500.00 / mg
- TargetMol Chemicals Inc.
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