2-[2-(2-methoxyethoxy)ethoxy]ethylamine
![2-[2-(2-methoxyethoxy)ethoxy]ethylamine Structure](CAS/GIF/74654-07-2.gif)
- CAS No.
- 74654-07-2
- Chemical Name:
- 2-[2-(2-methoxyethoxy)ethoxy]ethylamine
- Synonyms
- 2-(2-(2-methoxyethoxy)ethoxy)ethan-1-amine;MPEG3-NH2;NH3-PEG3-OME;m-PEG3-Amine;MeO-PEG3-NH2;Methyl-PEG3-amine;H2N-(CH2CH2O)3-Me;3,6,9-Trioxa-1-aminodecane;3,6,9-Trioxadecane-1-amine;2,5,8-trioxatridecane-10-aMine
- CBNumber:
- CB3899124
- Molecular Formula:
- C7H17NO3
- Molecular Weight:
- 163.21
- MDL Number:
- MFCD17215909
- MOL File:
- 74654-07-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-(2-(2-Methoxyethoxy)ethoxy) ethanamine ≥95% | 901158 | 5G | $354 |
| m-PEG3-Amine min. 95.0 % | M3686 | 200MG | $56 |
| m-PEG3-Amine min. 95.0 % | M3686 | 1G | $193 |
| 2-(2-(2-Methoxyethoxy)ethoxy)ethanamine | M220438 | 2.5g | $175 |
| 2-(2-(2-Methoxyethoxy)ethoxy)ethanamine | M220438 | 250mg | $45 |
| More product size | |||
| Boiling point | 106℃ (11 Torr) |
|---|---|
| Density | 0.978±0.06 g/cm3(Predicted) |
| refractive index | 1.4395 (589.3 nm 20℃) |
| storage temp. | 2-8°C |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 8.74±0.10(Predicted) |
| form | Oil |
| color | Colorless to light yellow |
| InChI | InChI=1S/C7H17NO3/c1-9-4-5-11-7-6-10-3-2-8/h2-8H2,1H3 |
| InChIKey | OKUWOEKJQRUMBW-UHFFFAOYSA-N |
| SMILES | C(N)COCCOCCOC |
| UNSPSC Code | 12352116 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P260-P280-P301+P312 |
| WGK Germany | WGK 3 |
| HS Code | 2922190090 |
| Storage Class | 10 - Combustible liquids |
2-[2-(2-methoxyethoxy)ethoxy]ethylamine price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 901158 | 2-(2-(2-Methoxyethoxy)ethoxy) ethanamine ≥95% | 74654-07-2 | 5G | $354 | 2026-03-19 | Buy |
| TCI Chemical | M3686 | m-PEG3-Amine min. 95.0 % | 74654-07-2 | 200MG | $56 | 2026-03-19 | Buy |
| TCI Chemical | M3686 | m-PEG3-Amine min. 95.0 % | 74654-07-2 | 1G | $193 | 2026-03-19 | Buy |
| TRC | M220438 | 2-(2-(2-Methoxyethoxy)ethoxy)ethanamine | 74654-07-2 | 2.5g | $175 | 2021-12-16 | Buy |
| TRC | M220438 | 2-(2-(2-Methoxyethoxy)ethoxy)ethanamine | 74654-07-2 | 250mg | $45 | 2021-12-16 | Buy |
2-[2-(2-methoxyethoxy)ethoxy]ethylamine Chemical Properties,Uses,Production
Description
m-PEG3-amine is a PEG reagent containing an amino group (NH2). The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
m-PEG3-amine whose chemical name 2-[2-(2-methoxyethoxy)ethoxy]ethylamine,it is a PROTAC bridge, belonging to the PEG class, which can be used to synthesize a series of PROTAC molecules, and can also be used for the synthesis of antibody drug conjugates (ADCs).
Synthesis
2-[2-(2-methoxyethoxy)ethoxy]ethylamine is an organic intermediate, which can be prepared from triethylene glycol monomethyl ether as raw material to prepare 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate, and then Reaction with sodium azide,and then Reacts with sodium azide to finally yield 3,6,9-trioxa-1-aminodecane.
IC 50
Cleavable Linker; PEGs
References
[1] Patent: WO2015/191433, 2015, A1. Location in patent: Paragraph 0041
[2] Chemische Berichte, 1980, vol. 113, # 5, p. 1691 - 1707
[3] Molecules, 2015, vol. 20, # 9, p. 16085 - 16102
[4] Chemistry - An Asian Journal, 2011, vol. 6, # 1, p. 149 - 156
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 48, p. 15461 - 15465
2-[2-(2-methoxyethoxy)ethoxy]ethylamine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| LAURENT | +8618100176782 | sun@laurentpeg.com | China | 365 | 58 |
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32469 | 58 |
View Lastest Price from 2-[2-(2-methoxyethoxy)ethoxy]ethylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-12 | m-PEG3-Amine
74654-07-2
|
US $0.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2026-01-28 | mPEG3-NH2
74654-07-2
|
US $0.00-0.00 / g | 1g | 98% | 300kg | LAURENT | |
 |
2025-10-13 | m-PEG3-Amine
74654-07-2
|
US $2.00-6.00 / kg | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- m-PEG3-Amine
74654-07-2
- US $0.00 / mg
- TargetMol Chemicals Inc.
-
- mPEG3-NH2
74654-07-2
- US $0.00-0.00 / g
- 98%
- LAURENT
-
- m-PEG3-Amine
74654-07-2
- US $2.00-6.00 / kg
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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