4-O-(Carboxymethyl)rifamycin
- CAS No.
- 13929-35-6
- Chemical Name:
- 4-O-(Carboxymethyl)rifamycin
- Synonyms
- C01848;Nacimycin;Nancimycin;Rifomycin B;NCI-145-604;Rifamycin B CRS;Rifamycin impurity A;Rifaximin EP Impurity B;Rifamycin EP Impurity A;Rifaximin impurity B (EP)
- CBNumber:
- CB3913884
- Molecular Formula:
- C39H49NO14
- Molecular Weight:
- 755.8
- MDL Number:
- MOL File:
- 13929-35-6.mol
| Melting point | 300° (dec 160-164°) |
|---|---|
| alpha | D20 -11° (methanol) |
| Boiling point | 730.16°C (rough estimate) |
| Density | 1.2421 (rough estimate) |
| refractive index | 1.5350 (estimate) |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated) |
| pka | 2.69±0.10(Predicted) |
| BRN | 604953 |
| Stability | Unstable in solution |
| FDA UNII | 8DDB535DJI |
SAFETY
Risk and Safety Statements
| Toxicity | LD50 in mice (mg/kg): 2040 i.v., >3000 i.p., s.c., and orally (Sensi, 1964) |
|---|
4-O-(Carboxymethyl)rifamycin price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R0900000 | Rifamycin B European Pharmacopoeia (EP) Reference Standard | 13929-35-6 | 25 mg | $236 | 2025-07-31 | Buy |
| Sigma-Aldrich | R0900000 | Rifamycin B European Pharmacopoeia (EP) Reference Standard | 13929-35-6 | r0900000 | $220 | 2024-03-01 | Buy |
| TRC | R508170 | Rifamycin B | 13929-35-6 | 50mg | $160 | 2021-12-16 | Buy |
| TRC | R508170 | Rifamycin B | 13929-35-6 | 500mg | $1295 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009903 | RIFAMYCIN B 95.00% | 13929-35-6 | 500MG | $1871.1 | 2021-12-16 | Buy |
4-O-(Carboxymethyl)rifamycin Chemical Properties,Uses,Production
Uses
A Rifamycin (R508200) derivative as antibacterial agent.
Uses
Rifamycin B (Rifaximin EP Impurity B) is a Rifamycin (R508200) derivative as antibacterial agent.
Definition
ChEBI: Rifamycin B is a carboxylic acid, an acetate ester, an organic heterotetracyclic compound and a member of rifamycins. It is a conjugate acid of a rifamycin B(2-).
Purification Methods
Rifamycin B forms yellow needles from *C6H6. Its solubilities are: H2O (0,027%), MeOH (2.62%) and EtOH (0.44%). It has UV max at 223, 304 and 245nm (A 1cm 555, 275 and 220). [Oppolzer & Prelog Helv Chim Acta 56 2287 1973, Oppolzer et al. Experientia 20 336 1964, X-ray: Brufani et al. Experientia 20 339 1964.]
4-O-(Carboxymethyl)rifamycin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
| Guangzhou PI PI BIOTECH INC | +86-020-81716320 +86-13602409664 | Sales@pipitech.com | China | 975 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15146 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9629 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
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