Geldanamycin-FITC
- CAS No.
- 2969156-01-0
- Chemical Name:
- Geldanamycin-FITC
- Synonyms
- Geldan-FITC;Geldanamycin-FITC
- CBNumber:
- CB39272847
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| Geldanamycin-FITC ≥98% (HPLC), from Streptomyces hygroscopicus | SML1277 | 1 mg | $328 |
Geldanamycin-FITC Chemical Properties,Uses,Production
Description
Geldanamycin-FITC is a novel geldanamycin fluorescent probe1?that may be used in a fluorescence polarization assay for HSP-90 inhibitors.2,3?May also be used for detection of cell surface HSP-90 and for other applications. Fluorescent geldanamycin probes have been used to characterize geldanamycin drug-target interactions for effective translation of?in vitro?pharmacology to cellular and?in vivo?efficacy.4
Uses
Geldanamycin-FITC is a novel geldanamycin fluorescent probe. Fluorescent geldanamycin probes have been used to characterize geldanamycin drug-target interactions for effective translation of in vitro pharmacology to cellular and in vivo efficacy.
IC 50
HSP90
References
[1] LAURA LLAUGER-BUFI . Synthesis of novel fluorescent probes for the molecular chaperone Hsp90[J]. Bioorganic & Medicinal Chemistry Letters, 2003, 13 22: Pages 3975-3978. DOI:10.1016/j.bmcl.2003.08.065
[2] JOUNGNAM KIM . Development of a Fluorescence Polarization Assay for the Molecular Chaperone Hsp90[J]. SLAS Discovery, 2004, 9 5: Pages 375-381. DOI:10.1177/1087057104265995
[3] CAROL AUSTIN . Fragment Screening Using Capillary Electrophoresis (CEfrag) for Hit Identification of Heat Shock Protein 90 ATPase Inhibitors[J]. SLAS Discovery, 2012, 17 7: Pages 868-876. DOI:10.1177/1087057112445785
[4] LATA T GOOLJARSINGH. A biochemical rationale for the anticancer effects of Hsp90 inhibitors: slow, tight binding inhibition by geldanamycin and its analogues.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2006: 7625-7630. DOI:10.1073/pnas.0602650103
Geldanamycin-FITC Preparation Products And Raw materials
Raw materials
Preparation Products
Geldanamycin-FITC Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd. | 0755-23251735 13302967066 | sales@geneseqtools.com | China | 1420 | 58 |
| Huaian Jiamu Biotechnology Co., Ltd. | 0517-83187139 18205232085 | cai@jiamu-bio.com | China | 2986 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
| StressMarq Biosciences Inc | 1250-294-9065 | info@stressmarq.com | China | 3181 | 58 |
| Enzo Biochem Inc | Enzo Biochem Inc. 13797054060 | Enzoname@qq.com | China | 6174 | 58 |
| MO-CHEM | 13851755987 | dingdalei@mo-chem.com.cn | China | 178 | 58 |
