Proteinase, Bothrops atrox serine
- CAS No.
- 9039-61-6
- Chemical Name:
- Proteinase, Bothrops atrox serine
- Synonyms
- D03352;Botropase;Defibrase (tn);Batroxobin (jan/inn);Bothrops venom proteinase;BATROXOBIN, FROM BOTHROPS ATROX;Proteinase, Bothrops atrox serine
- CBNumber:
- CB3931972
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00130918
- MOL File:
- Mol file
- MSDS File:
- SDS
| form | Solid |
|---|---|
| color | White to off-white |
| FDA UNII | 47RYF40GA9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H334-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P261-P285-P304+P341-P342+P311-P501 |
Proteinase, Bothrops atrox serine Chemical Properties, Uses, Production
Originator
Defibrase,Serono,W. Germany,1982
Uses
Defibrase, deinagkistrodonacutus is a proteolytic enzyme extraction of Agkistrodon halys venom. Defibrase can be used for degradation of fibrinogen. Defibrase can exacerbate myosin-induced EAM (experimental autoimmune myositis). Defibrase can be used for degradation of fibrinogen. Defibrase is commonly used for research of acute ischemic cerebrovascular disease, thromboangiitis obliterans, deep phlebitis and sudden deafness[1].
Manufacturing Process
The process for preparing the enzyme composition comprises treating an aqueous solution of the snake venom at a pH of about 4 to 6 with phenol or a phenol derivative in order to precipitate an insoluble complex containing the active venom fraction and decomposing the complex in order to release the thrombinlike enzyme composition.
Therapeutic Function
Hemostatic
References
[1] Wen-Jing L, et al. A new modified animal model of myosin-induced experimental autoimmune myositis enhanced by defibrase. Arch Med Sci. 2015 Dec 10;11(6):1272-8. DOI:10.5114/aoms.2015.52883
Proteinase, Bothrops atrox serine Preparation Products And Raw materials
Proteinase, Bothrops atrox serine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29091 | 58 |
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| Hu' nan Yunbang Pharmaceutical Co., Ltd. | 88532689 15386497078 | yunbang@yunbangapi.com | China | 6935 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 81148925 17391631969 | 1023@dideu.com | China | 9999 | 58 |
| Supplier | Advantage |
|---|---|
| Dideu Industries Group Limited | 58 |
| cjbscvictory | 58 |
| Hu' nan Yunbang Pharmaceutical Co., Ltd. | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 58 |
