factor VIII
- CAS No.
- Chemical Name:
- factor VIII
- Synonyms
- factor VIII;Human Factor VIII;Factor VIII B chain;Factor Ⅷ-related Antigen;Recombinant Human Factor VIII;Factor VIII B chain Rabbit pAb;Rabbit Anti-factor VIII antibody;Rabbit Anti-Factor VIII B chain antibody;Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody;Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody 2
- CBNumber:
- CB3946091
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01770461
- MOL File:
- Mol file
factor VIII price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | F0016-07 | Factor VIII PurifiedbyProteinAaffinitychromatographyfromtissueculturesupernatant. | 500ug | $878 | 2026-06-03 | Buy | |
| Usbiological | F0016 | Factor VIII PurifiedbyProteinGaffinitychromatography. | 100ug | $425 | 2026-06-03 | Buy | |
| Usbiological | F0016-02 | Factor VIII Purified.≥95%bySDS-PAGE. | 100ug | $665 | 2026-06-03 | Buy | |
| Usbiological | F0016 | Factor VIII PurifiedbyProteinGaffinitychromatography. | 250ug | $885 | 2026-06-03 | Buy | |
| Usbiological | 522847 | Factor VIII Purifiedbyimmunoaffinitychromatography. | 100ul | $736 | 2026-06-03 | Buy |
factor VIII Chemical Properties, Uses, Production
Description
Factor VIII, a recombinant DNA product, is useful for the management of bleeding episodes in patients with hemophilia A. A major advantage is that the synthetic version is free from HIV and hepatitis viruses. It should also prevent any shortages of this clotting factor.
Originator
Genetics Institute (U.S.A.)
brand name
Factorate;Hemofil;Humafac;Humanate;Hyate:c;Koate;Kryobulin;Profilate.
World Health Organization (WHO)
Factor VIII, a naturally occurring plasma protein fraction, is a vital component of the normal blood clotting mechanism which is deficient in haemophiliacs who require replacement therapy for both the treatment and prevention of bleeding. Factor VIII is extracted from the pooled plasma of a large number of donors and is presented as a concentrate. It has been recognized since 1984 that some viruses, and particularly the HIV (AIDS virus) could be transmitted to haemophiliacs from such preparations. As a result many regulatory authorities have issued new directives for the manufacture of blood products that avert this danger, by requiring the introduction of specific antiviral treatment measures during the manufacturing process. Manufacturers have withdrawn pre-existing preparations.
General Description
Antihemophilic factor VIII (recombinant), Recombinate,Kogenate, Bioclate, Helixate, is a plasma protein that functionsin the normal blood-clotting cascade by increasing theVmax for the activation of clotting factor X by factor IXa inthe presence of calcium ions and negatively charged phospholipids.Factor VIII is used in the treatment of hemophiliaA.
Recombinant factor VIII is indicated for the treatment ofclassical hemophilia (hemophilia A) and for the preventionand treatment of hemorrhagic episodes and perioperativemanagement of patients with hemophilia A. The drug is alsoindicated for the treatment of hemophilia A in persons whopossess inhibitors to factor VIII.
Recombinant factor VIII is supplied in sterile, singledosevials. The product is stabilized with human albuminand lyophilized. The product must be stored at 2°C to 8°C,without freezing. In some instances, the powder may bestored at room temperature for up to 3 months without lossof biological activity. Shaking of the reconstituted productshould be avoided because of the presence of the albumin.The drug must be administered by IV bolus or drip infusionwithin 3 hours of reconstitution.
factor VIII Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| Shanghai Bohu Biological Technology Co., Ltd. | 57763112 18930344717 | 3004987436@qq.com | China | 9989 | 58 |
| Shanghai Yansheng Industrial Co., Ltd. | 021-59989018 15201736385 | 3004965319@qq.com | China | 7806 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Huzhen Industrial Co., LTD | 58 |
| Shanghai Bohu Biological Technology Co., Ltd. | 58 |
| Shanghai Yansheng Industrial Co., Ltd. | 58 |
| TargetMol | 58 |
