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ChemicalBook >> CAS DataBase List >>Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Structure
Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- structure
CAS No.
2331259-44-8
Chemical Name:
Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
Synonyms
Poma-amide-PEG4-NH2;Pomalidomide-amino-PEG4-NH2;Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
CBNumber:
CB39757634
Molecular Formula:
C23H30N4O9
Molecular Weight:
506.51
MDL Number:
MOL File:
2331259-44-8.mol
Last updated:2025-04-18 09:52:12
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Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Properties

Boiling point 776.6±60.0 °C(Predicted)
Density 1.383±0.06 g/cm3(Predicted)
pka 10.68±0.40(Predicted)

Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ACHEMBLOCK V143434 14-Amino-N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]-3,6,9,12-tetraoxatetradecan-1-amide 98% 2331259-44-8 1G $2220 2026-05-27 Buy
Product number Packaging Price Buy
V143434 1G $2220 Buy

Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Chemical Properties, Uses, Production

Uses

Pomalidomide-amino-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Suppliers

Global Suppliers ( 7)
Supplier Tel Email Country ProdList Advantage
Zhengzhou convergence chemical co., LTD 037155153829 18003835034 3897192574@qq.com China 9982 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2223443625@qq.com China 7998 58
Wuhan Augda Biotechnology Co., Ltd 15071299552 262933239@qq.com China 7201 58
Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. +86-027-59232304 15387063101 1276242629@qq.com China 9977 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Dipag (Weinan) Biotechnology Co., Ltd 15114901355 1002921772@qq.com China 190 58
HANGZHOU LAURET BIOTECHOLOGY CO.,LTD 15306536782 3839324846@qq.com China 149 58
Supplier Advantage
Zhengzhou convergence chemical co., LTD 58
Hubei Kele Fine Chemical Co., Ltd 58
Wuhan Augda Biotechnology Co., Ltd 58
Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 58
Dipag (Weinan) Biotechnology Co., Ltd 58
HANGZHOU LAURET BIOTECHOLOGY CO.,LTD 58

2331259-44-8 (Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-) Related Search:

Thalidomide-NH-PEG2-C2-NH2 hydrochloride (S,R,S)-AHPC-Me-C6-NH2 -PEG4-amine 2,6-Piperidinedione, 3-[4-[[2-(2-aminoethoxy)ethyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-, hydrochloride (1:2) E3 ligase Ligand-Linker Conjugates 3
E3 ligase Ligand-Linker Conjugates 12

1of2

Acetamide, 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Poma-amide-PEG4-NH2 Pomalidomide-amino-PEG4-NH2 2331259-44-8