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2-Iodophenol

2-Iodophenol Structure
2-Iodophenol structure
CAS No.
533-58-4
Chemical Name:
2-Iodophenol
Synonyms
O-IODOPHENOL;ORTHO-IODOPHENOL;DK807;NSC 9245;o-Jodfenol;2-Jodfenol;2-iodo-pheno;2-IODOPHENOL;o-iodo-pheno;2-lodophenol
CBNumber:
CB4130718
Molecular Formula:
C6H5IO
Molecular Weight:
220.01
MDL Number:
MFCD00013963
MOL File:
533-58-4.mol
MSDS File:
SDS
Last updated:2026-04-10 10:27:14
Product description Number Pack Size Price
2-Iodophenol 98% 281409 5g $66.3
2-Iodophenol 98% 281409 25g $133
2-Iodophenol >99.0%(GC) I0460 5g $37
2-Iodophenol >99.0%(GC) I0460 25g $121
2-Iodophenol I717500 100g $395
More product size
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2-Iodophenol Properties

Melting point 37-40 °C (lit.)
Boiling point 186-187 °C/160 mmHg (lit.)
Density 1.947 g/mL at 25 °C (lit.)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
pka 8.51(at 25℃)
form Crystalline Powder or Crystalline Low Melting Mass
color White or cream to brown
Specific Gravity 1.947
Water Solubility slightly soluble
Sensitive Light Sensitive
Merck 14,5035
BRN 1855300
Henry's Law Constant 1.4×101 mol/(m3Pa) at 25℃, Abraham et al. (1994)
Stability Stable. Incompatible with strong oxidizing agents.
InChI 1S/C6H5IO/c7-5-3-1-2-4-6(5)8/h1-4,8H
InChIKey KQDJTBPASNJQFQ-UHFFFAOYSA-N
SMILES Oc1ccccc1I
CAS DataBase Reference 533-58-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII F27L34A8B9
NIST Chemistry Reference Phenol, 2-iodo-(533-58-4)
EPA Substance Registry System Phenol, 2-iodo- (533-58-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  SL5500000
TSCA  TSCA listed
HazardClass  IRRITANT, LIGHT SENSITIVE
HS Code  29081000
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

2-Iodophenol price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 281409 2-Iodophenol 98% 533-58-4 5g $66.3 2026-03-19 Buy
Sigma-Aldrich 281409 2-Iodophenol 98% 533-58-4 25g $133 2026-03-19 Buy
TCI Chemical I0460 2-Iodophenol >99.0%(GC) 533-58-4 5g $37 2026-03-19 Buy
TCI Chemical I0460 2-Iodophenol >99.0%(GC) 533-58-4 25g $121 2026-03-19 Buy
TRC I717500 2-Iodophenol 533-58-4 100g $395 2021-12-16 Buy
Product number Packaging Price Buy
281409 5g $66.3 Buy
281409 25g $133 Buy
I0460 5g $37 Buy
I0460 25g $121 Buy
I717500 100g $395 Buy

2-Iodophenol Chemical Properties,Uses,Production

Chemical Properties

colorless needle-like crystals or Pale Yellow Low Melting Solid. Slightly soluble in water, easily soluble in organic solvents such as ethanol and ether.

Uses

2-Iodophenol is used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity and 3,3-disubstituted-2,3-dihydrobenzofurans. Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield.

Application

2-Iodophenol is a halophenol with antifungal activity. 2-Iodophenol was used in the synthesis of:
aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity
3,3-disubstituted-2,3-dihydrobenzofurans
1,3,5-substituted benzenes.
2-Iodophenol is also used as additive tracers for resist plasm a etching and suzuki reaction.

Preparation

synthesis of 2-iodophenol: phenol (1a) to react with 0.5 equivalent of iodine and 1 equivalent of hydrogen peroxide in water at room temperature for 24 h, 2,6-diiodophenol (2a) and 2-iodophenol (3) were isolated in yields of 21 and 49%, respectively.
synthesis of 2-iodophenol

Definition

ChEBI: 2-iodophenol is a 2-halophenol and an iodophenol.

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 5281, 1988 DOI: 10.1021/jo00257a014

General Description

Rapid palladium-catalyzed carbonylative cyclization reactions of 2-iodophenol with various alkyne under microwave irradiation using Mo(CO)6 as the CO source has been investigated.

Purification Methods

Crystallise 2-iodophenol from CHCl3 or diethyl ether. The acetate has m 65-66o (from MeOH). [Beilstein 6 H 208, 6 II 198, 6 III 774, 6 IV 1074.]

2-Iodophenol synthesis

1008106-86-2
533-58-4
Synthesis of 2-Iodophenol from 2-IODOPHENYLBORONIC ACID

2-Iodophenol Preparation Products And Raw materials

Raw materials

2-IODOPHENYL 4-METHYLPHENYLSULFONATE 1-Iodo-2-prop-2-ynoxybenzene O-prenyl-2-iodophenol 2-IODOPHENYLBORONIC ACID 1-IODO-2-(PROP-2-EN-1-YLOXY)BENZENE(WXG01388)
2,6-diiodophenol(WX191341)

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Preparation Products

Benzofuran, 2,3-dihydro-2,2,3-trimethyl- 2H-1,3-Benzoxazine-2,4(3H)-dione 2-Hydroxystyrene Dibenzofuran, 1-nitro- 1-IODO-2-PHENOXY-BENZENE
2-ETHYNYL-PHENOL 2-Hydroxybenzophenone PHENYL PROPARGYL ETHER

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2-Iodophenol Suppliers

Global( 453)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5237 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29640 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13815 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21592 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29823 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58

View Lastest Price from 2-Iodophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Iodophenol pictures 2026-03-20 2-Iodophenol
533-58-4
 US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Iodophenol pictures 2025-12-01 2-Iodophenol
533-58-4
 US $0.00 / kg 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2-Iodophenol pictures 2025-09-25 2-Iodophenol
533-58-4
 US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
  • 2-Iodophenol pictures
  • 2-Iodophenol
    533-58-4
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • 2-Iodophenol pictures
  • 2-Iodophenol
    533-58-4
  • US $0.00 / kg
  • 99%
  • Shaanxi Dideu New Materials Co. Ltd
  • 2-Iodophenol pictures
  • 2-Iodophenol
    533-58-4
  • US $100.00-1.00 / KG
  • 99%
  • Henan Fengda Chemical Co., Ltd

2-Iodophenol Spectrum

2-Iodophenol(533-58-4)MS2-Iodophenol(533-58-4)1HNMR2-Iodophenol(533-58-4)13CNMR2-Iodophenol(533-58-4)IR12-Iodophenol(533-58-4)IR22-Iodophenol(533-58-4)IR3

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