rac-Paroxetine-d4 Hydrochloride
- CAS No.
- 2714485-95-5
- Chemical Name:
- rac-Paroxetine-d4 Hydrochloride
- Synonyms
- rac-Paxil-d4;rac-Aropax-d4;rac-Deroxat-d4;rac-Seroxat-d4;D4-Paroxetine HCl;rel-Paroxetine (hydrochloride);rac-3-[(1,3-Benzod-d4-ioxol-5-yloxy)methyl]-4-(4-fluorophenyl-d4)piperidine Hydrochloride;(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(2,3,5,6-tetradeuterio-4-fluorophenyl)piperidine
- CBNumber:
- CB413162540
- Molecular Formula:
- C19H16D4FNO3.ClH
- Molecular Weight:
- 369.85
- MDL Number:
- MOL File:
- 2714485-95-5.mol
- MSDS File:
- SDS
rac-Paroxetine-d4 Hydrochloride price
rac-Paroxetine-d4 Hydrochloride Chemical Properties, Uses, Production
Uses
Paroxetine-d4 (hydrochloride) is deuterium labeled Paroxetine (hydrochloride). Paroxetine hydrochloride is a potent selective serotonin-reuptake inhibitor, commonly prescribed as an and has GRK2 inhibitory ability with IC50 of 14μM. Paroxetine hydrochloride can be used for the research of depressive disorder[1][2][3].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Liu RP, et al. Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling. J Neuroinflammation. 2014 Mar 12;11:47. DOI:10.1186/1742-2094-11-47
[3] Wang Q, et al. Paroxetine alleviates T lymphocyte activation and infiltration to joints of collagen-induced arthritis. Sci Rep. 2017 Mar 28;7:45364. DOI:10.1038/srep45364
[4] Lassen TR, et al. Effect of paroxetine on left ventricular remodeling in an in vivo rat model of myocardial infarction. Basic Res Cardiol. 2017 May;112(3):26. DOI:10.1007/s00395-017-0614-5
[5] Zarei M, et al. Paroxetine attenuates the development and existing pain in a rat model of neurophatic pain. Iran Biomed J. 2014;18(2):94-100. DOI:10.6091/ibj.1282.2013
[6] Waldschmidt HV, et al. Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine. J Med Chem. 2017 Apr 13;60(7):3052-3069. DOI:10.1021/acs.jmedchem.7b00112
rac-Paroxetine-d4 Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
rac-Paroxetine-d4 Hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cato Research Chemicals Inc. | 020-81960175-877 18933936954 | tianwen.zhan@cato-chem.com | China | 7335 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| ShangHai ZskBio CO., LTD | 021-58056897 15399714481 | info@zsklab.com | China | 7539 | 58 |
| TLC Pharmaceutical Standards Ltd. | 18012923235 | chinasales04@tlcstandards.com.cn | China | 8143 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| Cato Research Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| ShangHai ZskBio CO., LTD | 58 |
| TLC Pharmaceutical Standards Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Latest Price from rac-Paroxetine-d4 Hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-11 | Paroxetine-D4 hydrochloride
2714485-95-5
|
10g | TargetMol Chemicals Inc. |
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- Paroxetine-D4 hydrochloride
2714485-95-5
- TargetMol Chemicals Inc.
