epiyangambin
- CAS No.
- 24192-64-1
- Chemical Name:
- epiyangambin
- Synonyms
- epiyangambin;O,O-Dimethyllirioresinol A;Lirioresinol A dimethyl ether;(+)-Epipinoresinol dimethyl ether;1,4-Bis(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan;3,6-bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan;(1S,3aβ,6aβ)-1β,4α-Bis(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan;(1S,3aβ,6aβ)-Tetrahydro-1β,4α-bis(3,4-dimethoxyphenyl)-1H,3H-furo[3,4-c]furan;(1S)-1β,4α-Bis(3,4-dimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan;1H,3H-Furo[3,4-c]furan, tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-, (1R,3aR,4S,6aR)-
- CBNumber:
- CB41336142
- Molecular Formula:
- C24H30O8
- Molecular Weight:
- 446.49
- MDL Number:
- MOL File:
- 24192-64-1.mol
epiyangambin Chemical Properties,Uses,Production
Uses
Epiyangambin is a competitive platelet activating factor receptor (PAF) antagonist that dose-dependently inhibits PAF-induced platelet aggregation. Epiyangambin also inhibits the growth of human colon cancer cells (SW480 cells)[1][2].
in vivo
Epiyangambin (20 mg/kg) significantly inhibits PAF (platelet activating factor)-induced thrombocytopenia in rats[2].
References
[1] Hausott B, et al. Naturally occurring lignans efficiently induce apoptosis in colorectal tumor cells. J Cancer Res Clin Oncol. 2003 Oct;129(10):569-76. DOI:10.1007/s00432-003-0461-7
[2] Castro-Faria-Neto HC, et al. Pharmacological profile of epiyangambin: a furofuran lignan with PAF antagonist activity. J Lipid Mediat. 1993 May;7(1):1-9. PMID:8358020
epiyangambin Preparation Products And Raw materials
Raw materials
Preparation Products
epiyangambin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5653 | 65 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15178 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 3004654993@qq.com | China | 8913 | 60 |
| Absin Bioscience Inc. | 021-38015121 18438616290 | wulan@absin.cn | China | 24731 | 58 |
| Shanghai Binsui Biotechnology Co., Ltd. | 18301908279 18301908279 | 1292752157@qq.com | China | 8483 | 58 |