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3,5-Bis(trifluoromethyl)bromobenzene

3,5-Bis(trifluoromethyl)bromobenzene Structure
3,5-Bis(trifluoromethyl)bromobenzene structure
CAS No.
328-70-1
Chemical Name:
3,5-Bis(trifluoromethyl)bromobenzene
Synonyms
1-BROMO-3,5-BIS(TRIFLUOROMETHYL)BENZENE;3,5-BIS(TRIFLUOROMETHYL)-1-BROMOBENZENE;1,3-BIS(TRIFLUOROMETHYL)-5-BROMOBENZENE;3,5-Bis(trifluoromethyl)phenyl bromide;MBT-BR;1,3-Bis(trifL;1-BROMO-3,5-BIS;)-5-bromobenzene;TRIFLUOROMETHYL BROMOBENZENE;3,5-Bis(trifluoromethly)b...
CBNumber:
CB4137843
Molecular Formula:
C8H3BrF6
Molecular Weight:
293
MDL Number:
MFCD00000381
MOL File:
328-70-1.mol
MSDS File:
SDS
Last updated:2025-09-18 19:10:02
Product description Number Pack Size Price
1,3-Bis(trifluoromethyl)-5-bromobenzene 99% 290157 10g $60.41
1,3-Bis(trifluoromethyl)-5-bromobenzene 99% 290157 50g $149.41
1-Bromo-3,5-bis(trifluoromethyl)benzene >98.0%(GC) B1753 10g $16
1-Bromo-3,5-bis(trifluoromethyl)benzene >98.0%(GC) B1753 25g $29
3,5-Bis(trifluoromethyl)bromobenzene B412888 5g $75
More product size
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3,5-Bis(trifluoromethyl)bromobenzene Properties

Melting point −16 °C(lit.)
Boiling point 154 °C(lit.)
Density 1.699 g/mL at 25 °C(lit.)
refractive index n20/D 1.427(lit.)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Sparingly)
form Liquid
Specific Gravity 1.699
color Clear colorless to slightly yellow
Water Solubility Immiscible with water.
BRN 2123669
InChIKey CSVCVIHEBDJTCJ-UHFFFAOYSA-N
CAS DataBase Reference 328-70-1(CAS DataBase Reference)
NIST Chemistry Reference 3,5-Bis(trifluoromethyl)bromobenzene(328-70-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  37/39-26-36-24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29036990
NFPA 704
1
2 0

3,5-Bis(trifluoromethyl)bromobenzene price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 290157 1,3-Bis(trifluoromethyl)-5-bromobenzene 99% 328-70-1 10g $60.41 2025-07-31 Buy
Sigma-Aldrich 290157 1,3-Bis(trifluoromethyl)-5-bromobenzene 99% 328-70-1 50g $149.41 2025-07-31 Buy
TCI Chemical B1753 1-Bromo-3,5-bis(trifluoromethyl)benzene >98.0%(GC) 328-70-1 10g $16 2025-07-31 Buy
TCI Chemical B1753 1-Bromo-3,5-bis(trifluoromethyl)benzene >98.0%(GC) 328-70-1 25g $29 2025-07-31 Buy
TRC B412888 3,5-Bis(trifluoromethyl)bromobenzene 328-70-1 5g $75 2021-12-16 Buy
Product number Packaging Price Buy
290157 10g $60.41 Buy
290157 50g $149.41 Buy
B1753 10g $16 Buy
B1753 25g $29 Buy
B412888 5g $75 Buy

3,5-Bis(trifluoromethyl)bromobenzene Chemical Properties,Uses,Production

Chemical Properties

clear colourless to slightly yellow liquid

Uses

1,3-Bis(trifluoromethyl)-5-bromobenzene is used to prepare the tetrakis[3,5-bis(trifluoromethyl)phenyl]borate ion, which acts as a stabilizing counterion for electrophilic organic and organometallic cations.

Synthesis Reference(s)

The Journal of Organic Chemistry, 68, p. 3695, 2003 DOI: 10.1021/jo026903n

Synthesis

1,3-Bis(trifluoromethyl)-benzene

402-31-3

3,5-Bis(trifluoromethyl)bromobenzene

328-70-1

Example 1: 1,3-bis(trifluoromethyl)benzene (1 kg) was slowly added to concentrated sulfuric acid (4 kg) while stirring the reaction mixture. The mixture was cooled to 5°C and 1,3-dibromo-5,5-dimethylglycolide (DBDMH, 668g) was added in batches over a period of 4 hours while maintaining the temperature between 0°C and 10°C. After completion of the reaction, the mixture was allowed to stand and layered to separate the organic phase. The organic phase was washed sequentially with water and dilute sodium bisulfite solution to remove residual acid and oxidants. Finally, the organic phase was purified by fractional distillation to afford 3,5-bis(trifluoromethyl)bromobenzene (1100 g, 99% purity, 80% yield).

References

[1] Journal of Organic Chemistry, 2003, vol. 68, # 9, p. 3695 - 3698
[2] Journal of Organic Chemistry USSR (English Translation), 1991, vol. 27, # 1.2, p. 108 - 112
[3] Zhurnal Organicheskoi Khimii, 1991, vol. 27, # 1, p. 125 - 129
[4] Tetrahedron Letters, 1998, vol. 39, # 52, p. 9621 - 9622
[5] Synlett, 1999, # 8, p. 1245 - 1246

3,5-Bis(trifluoromethyl)bromobenzene Preparation Products And Raw materials

Raw materials

1,3-Bis(trifluoromethyl)-benzene

Preparation Products

3,5-Bis(trifluoromethyl)benzoic acid BIS(3,5-DI(TRIFLUOROMETHYL)PHENYL)CHLOROPHOSPHINE METHYL 3,5-BIS(TRIFLUOROMETHYL)BENZOATE 3,5-BIS(TRIFLUOROMETHYL)ANISOLE 3,5-Bis(trifluoromethyl)phenol
3,5-Bis(trifluoromethyl)phenylacetonitrile CarbaMic acid, N-[(1S)-2-[3,5-bis(trifluoroMethyl)phenyl]-1-Methyl-2-oxoethyl]-, phenylMethyl ester tert-butyl 3,5-bis(trifluoromethyl)phenylcarbamate BIS[BIS(3,5-DITRIFLUOROMETHYLPHENYL)PHOSPHINO]METHANE

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3,5-Bis(trifluoromethyl)bromobenzene Suppliers

Global( 538)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Xinchem Co., Ltd.
+86-021-34123252 +8618049800532 xinchem@xinchem.com China 49 58
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		+8613288715578 sales@sichuanzyyt.com China 12247 58
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
Zhengzhou Anbu Chem Co.,Ltd 		+86-0371-88006763; +8615988602810 sales@anbuchem.com China 3000 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20175 58
Hebei Zhuanglai Chemical Trading Co Ltd 		+86-16264648883 niki@zlchemi.com China 7245 58
Hebei Junhua Import and Export Co., LTD 		+85259680964 junhua1@hb-junhua.com China 933 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29734 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13451 58
Supplier Advantage
Shanghai Xinchem Co., Ltd.
58
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Zhengzhou Anbu Chem Co.,Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Hebei Zhuanglai Chemical Trading Co Ltd 		58
Hebei Junhua Import and Export Co., LTD 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58

View Lastest Price from 3,5-Bis(trifluoromethyl)bromobenzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-Bis(trifluoromethyl)bromobenzene pictures 2025-10-20 3,5-Bis(trifluoromethyl)bromobenzene
328-70-1
 US $0.00-0.00 / kg 1kg 98% 1000 Hebei Junhua Import and Export Co., LTD
1-bromo-3,5-bis(trifluoromethyl)benzene pictures 2025-10-20 1-bromo-3,5-bis(trifluoromethyl)benzene
328-70-1
 US $50.00 / KG 1KG 98% 20 tons Speranza Chemical Co., Ltd.
3,5-Bis(trifluoromethyl)bromobenzene pictures 2025-10-20 3,5-Bis(trifluoromethyl)bromobenzene
328-70-1
 US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD

3,5-Bis(trifluoromethyl)bromobenzene Spectrum

3,5-Bis(trifluoromethyl)bromobenzene(328-70-1)MS3,5-Bis(trifluoromethyl)bromobenzene(328-70-1)1HNMR3,5-Bis(trifluoromethyl)bromobenzene(328-70-1)13CNMR3,5-Bis(trifluoromethyl)bromobenzene(328-70-1)IR13,5-Bis(trifluoromethyl)bromobenzene(328-70-1)Raman

328-70-1(3,5-Bis(trifluoromethyl)bromobenzene)Related Search:

4-Bromobenzotrifluoride Xylene Trifluoromethanesulfonic acid 2-Bromofluorobenzene 2-Methylbenzotrifluoride
4-Bromofluorobenzene 2-(Trifluoromethyl)benzoic acid 3-Bromobenzotrifluoride Bromobenzene 3-Aminobenzotrifluoride
3-(Trifluoromethyl)benzaldehyde 3,5-Bis(trifluoromethyl)benzoic acid 2-Amino-5-bromobenzotrifluoride 3,5-Bis(trifluoromethyl)benzoyl chloride Benzene
3-METHYLBENZOTRIFLUORIDE 1,1-Difluoroethane Bromine

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TRIFLUOROMETHYL BROMOBENZENE 1-Bromo-3,5-bis(trifluoromethyl)benzene, 3,5-Bis(trifluoromethyl)bromobenzene 3,5-Bis(trifluoromethyl)phenyl bromide 1-BROMO-3,5-BIS 3,5-Bis(trifluoromethyl)-5-bromobenzene ,99% 3,5-Bis(trifluoromethly)b... 3,5-Bis(trifluoroMethly)broMobenzene 3,5-Bis(trifluoroMethyl)broMobenzene, 99% 10GR 3,5-Bis(trifluoroMethyl)broMobenzene, 99% 50GR 1,3-Bis(trifluoromethyl)-5-bromobenzene 99% 5-Bromo-alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-m-xylene 1,3-Bis(trifluoroMethyl)-5-broMobenzene, 97+% 3,5-2,5-bis(trifluoromethyl)bromobenzene 3,5-bis-trifluoromethyl benzene bromide 3,5-Bis(trifluoromethyl)-1-bromobenzene for synthesis MBT-BR 5-BROMO-1,3-BIS(TRIFLUOROMETHYL)BENZENE 3,5-BIS(TRIFLUOROMETHYL)BROMINE BENZENE 3,5-BIS(TRIFLUOROMETHYL)BROMOBENZENE 3,5-BIS(TRIFLUOROMETHYL)-1-BROMOBENZENE 3,5-DI(TRIFLUOROMETHYL)BROMOBENZENE 1,3-BIS(TRIFLUOROMETHYL)-5-BROMOBENZENE 1-BROMO-3,5-BIS(TRIFLUOROMETHYL)BENZENE Benzene, 1-bromo-3,5-bis(trifluoromethyl)- m-Xylene, 5-bromo-alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro- 3,5-BIS(TRIFLUOROMETHYL)BROMOBENZENE, 99 % 3,5-Bis(Trifluoromethyl)-Bromo 3,5-BIS(TRIFLUOROMETHYL)BROMOBENZENE 98.00% )-5-bromobenzene 1,3-Bis(trifL 3,5-Bis(trifluoromethyl)bromobenzene （Aprepitant） 1-Bromo-3,5-bis(trifluoromethyl)benzene > 1-Brom-3,5-bis(trifluormethyl)benzol 3,5-Bis(trifluoromethyl)bromobenzene ISO 9001：2015 REACH 5-Bis(trifluoromethyl)bromobenzene 3,5-Bis(trifluormethyl)bromobenzene 3,5-difluoromethylbromobenzene 328-70-1 CF32C6H3Br C8H3BrF6 ARYL HALIDE C8 Aryl Building Blocks Halogenated Hydrocarbons Organic Building Blocks Fluorobenzene PHARMACEUTICAL INTERMEDIATES Aromatic Hydrocarbons (substituted) & Derivatives Fluorides Trifluoromethylbenzene serise alkyl bromide Morpholines/Thiomorpholines ,Isoxazoles API intermediates Miscellaneous bc0001