SDZ 281 977
- CAS No.
- 150779-71-8
- Chemical Name:
- SDZ 281 977
- Synonyms
- SDZ-LAP 977;SDZ 281 977;SDZ281 977,SDZ-281-977,SDZ281977;Methyl 5-[2-(2,5-dimethoxyphenyl)ethyl]-2-hydroxybenzoate;Benzoic acid, 5-[2-(2,5-dimethoxyphenyl)ethyl]-2-hydroxy-, methyl ester
- CBNumber:
- CB41381076
- Molecular Formula:
- C18H20O5
- Molecular Weight:
- 316.35
- MDL Number:
- MFCD00920170
- MOL File:
- 150779-71-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SDZ 281 977 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-6659 | SDZ281-977 98.00% | 150779-71-8 | 5mg | $325 | 2026-06-04 | Buy |
| ChemScene | CS-6659 | SDZ281-977 98.00% | 150779-71-8 | 10mg | $531 | 2026-06-04 | Buy |
| ChemScene | CS-6659 | SDZ281-977 98.00% | 150779-71-8 | 25mg | $1062 | 2026-06-04 | Buy |
| Biosynth | AGA77971 | Methyl 5-[2-(2,5-dimethoxyphenyl)ethyl]-2-hydroxybenzoate | 150779-71-8 | 5mg | $1671.3 | 2026-06-04 | Buy |
| ChemScene | CS-6659 | SDZ281-977 98.00% | 150779-71-8 | 50mg | $1625 | 2026-06-04 | Buy |
SDZ 281 977 Chemical Properties, Uses, Production
Uses
SDZ 281-977 is a derivative of the EGF receptor tyrosine kinase inhibitor Lavendustin A.
in vivo
Nude mice bearing A431 human vulvar carcinomas receive intravenous injections of SDZ 281-977 (1-10 mg/kg) for 4 weeks. This treatment results in a dose-dependent inhibition of tumor growth. Orally administered SDZ 281-977 (30 mg/kg) induces a 54% inhibition of A431 tumor growth after 3 weeks of treatment. The above regimens are well tolerated. No significant change in body weight occurred during treatment[1].
References
[1] Cammisuli S, et al. SDZ 281-977: a modified partial structure of lavendustin A that exerts potent and selective antiproliferative activities in vitro and in vivo. Int J Cancer. 1996 Jan 26;65(3):351-9. DOI:10.1002/(SICI)1097-0215(19960126)65:33.0.CO;2-D
SDZ 281 977 Preparation Products And Raw materials
Raw materials
Preparation Products
SDZ 281 977 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Beijing xinyanhui pharmaceutical research and development co., LTD | 13969155946 | 1461866103@qq.com | China | 16103 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
| Guangzhou Ruidi Biotechnology Co., Ltd. | 020-82099279 18988941402 | sales@ubiochem.com | China | 9998 | 58 |
