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BOC-D-PRO-OME

BOC-D-PRO-OME structure

CAS No.: 73323-65-6

Chemical Name:: BOC-D-PRO-OME

Synonyms: (2R)-pyrroL;BOC-D-PRO-OME;BOC-D-PYRD(2)-OME;idine-1,2-dicarboxyL;Boc-D-methyl proline;BOC-D-PRO-OME USP/EP/BP;Bok - D - Methyl proline;BOC-D-PROLINE METHYL ESTER;N-Boc-D-proline methyl este;N-BOC-D-PROLINE METHYL ESTER

CBNumber:: CB4138390

Molecular Formula:: C11H19NO4

Molecular Weight:: 229.27

MDL Number:: MFCD00190828

MOL File:: 73323-65-6.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:47

Product description	Number	Pack Size	Price
N-(tert-Butoxycarbonyl)-D-proline Methyl Ester >98.0%(GC)	B4787	1g	$26
N-(tert-Butoxycarbonyl)-D-proline Methyl Ester >98.0%(GC)	B4787	5g	$76
N-Boc-D-prolineMethylEster	B664205	10g	$225
Boc-D-proline methyl ester	265160	500mg	$333
Boc-D-proline methyl ester ≥ 99% (HPLC)	06651	5G	$352
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BOC-D-PRO-OME Properties

Boiling point	288.6±33.0 °C(Predicted)
Density	1.120±0.06 g/cm3(Predicted)
refractive index	1.4510-1.4550
storage temp.	Sealed in dry,2-8°C
solubility	Soluble in DMSO.
pka	-3.35±0.40(Predicted)
form	Oil
color	Clear Colourless
optical activity	59.8°(C=0.01g/ml MEOH)
InChI	InChI=1S/C11H19NO4/c1-11(2,3)16-10(14)12-7-5-6-8(12)9(13)15-4/h8H,5-7H2,1-4H3/t8-/m1/s1
InChIKey	WVDGSSCWFMSRHN-MRVPVSSYSA-N
SMILES	N1(C(OC(C)(C)C)=O)CCC[C@@H]1C(OC)=O
CAS DataBase Reference	73323-65-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS06,GHS08,GHS09

Signal word

Danger

Hazard statements

H311-H314-H371-H411

Precautionary statements

P501-P273-P260-P270-P264-P280-P391-P308+P311-P361+P364-P303+P361+P353-P301+P330+P331-P304+P340+P310-P305+P351+P338+P310-P405

HazardClass

IRRITANT

HS Code

2933998090

NFPA 704

	1
0		0

BOC-D-PRO-OME price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B4787	N-(tert-Butoxycarbonyl)-D-proline Methyl Ester >98.0%(GC)	73323-65-6	1g	$26	2025-07-31	Buy
TCI Chemical	B4787	N-(tert-Butoxycarbonyl)-D-proline Methyl Ester >98.0%(GC)	73323-65-6	5g	$76	2025-07-31	Buy
TRC	B664205	N-Boc-D-prolineMethylEster	73323-65-6	10g	$225	2021-12-16	Buy
Usbiological	265160	Boc-D-proline methyl ester	73323-65-6	500mg	$333	2021-12-16	Buy
Chem-Impex	06651	Boc-D-proline methyl ester ≥ 99% (HPLC)	73323-65-6	5G	$352	2021-12-16	Buy

Product number	Packaging	Price	Buy
B4787	1g	$26	Buy
B4787	5g	$76	Buy
B664205	10g	$225	Buy
265160	500mg	$333	Buy
06651	5G	$352	Buy

BOC-D-PRO-OME Chemical Properties,Uses,Production

Uses

N-Boc-D-proline methyl ester is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff fields.

Synthesis

37784-17-1

74-88-4

73323-65-6

To a mixture of (R)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid (5.8 g, 27 mmol) and potassium carbonate (8.6 g, 62 mmol) in tetrahydrofuran (160 mL) was added iodomethane (4.0 mL, 65 mmol). The reaction mixture was heated to reflux for 17 hours and subsequently cooled to room temperature. The reaction mixture was filtered and the filtrate was concentrated under reduced pressure. The crude product was purified by automated column chromatography using petroleum ether/ethyl acetate (3:1, v/v) as eluent to afford (R)-1-tert-butyl 2-methyl pyrrolidine-1,2-dicarboxylate (6.0 g, 65% yield) as a yellow oil.

References

[1] Patent: WO2013/131018, 2013, A1. Location in patent: Page/Page column 38

BOC-D-PRO-OME Preparation Products And Raw materials

Raw materials

N-Boc-D-proline Iodomethane Potassium carbonate Tetrahydrofuran

Preparation Products

D-1-N-BOC-PROLINAMIDE Boc-L-Proline-methyl ester (S)-tert-butyl 2-(2-aminothiazol-4-yl)pyrrolidine-1-carboxylate

BOC-D-PRO-OME Suppliers

Global( 195)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29799	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20284	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Dideu Industries Group Limited	58

View Lastest Price from BOC-D-PRO-OME manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-20	BOC-D-PRO-OME 73323-65-6	US $1.00 / KG	1KG	99%	KG/T	Career Henan Chemical Co

BOC-D-PRO-OME
73323-65-6
US $1.00 / KG
99%
Career Henan Chemical Co

BOC-D-PRO-OME Spectrum

BOC-D-PRO-OME(73323-65-6)¹HNMR

73323-65-6(BOC-D-PRO-OME)Related Search:

D-Proline N-Boc-D-proline 1-Boc-Pyrrolidine Boc-L-Pro-OMe (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

BOC-D-PRO-OME 1-BOC-D-PYROGLUTAMIC ACID ETHYL ESTER (2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate N-Boc-Trans-4-Hydroxy-D-proline methyl ester Boc-lle-Pro-OMe

(R)-N-BOC-5-METHOXYCARBONYL-2-PYRROLIDINONE BOC-D-HYP-OTBU BOC-ALA-PRO-OME BOC-ILE-PRO-OME (2R,4S)-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER

(2R,4R)-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER (R)-1-tert-butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate

1of4

BOC-D-PROLINE METHYL ESTER BOC-D-PRO-OME BOC-D-PYRD(2)-OME R-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER N-ALPHA-T-BUTOXYCARBONYL-D-PROLINE METHYL ESTER N-ALPHA-T-BUTOXYCARBONYL-D-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER N-tert-Butoxycarbonyl-D-Proline methyl ester BOC-D-PROLINE METHYLESTER LIQUID N-BOC-D-PROLINE METHYL ESTER O1-tert-Butyl O2-methyl (2R)-pyrrolidine-1,2-dicarboxylate 1-O-tert-butyl 2-O-methyl (2R)-pyrrolidine-1,2-dicarboxylate (R)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 1-tert-Butyl 2-methyl (2R)-pyrrolidine-1,2-dicarboxylate N-Boc-D-proline methyl este (R)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate (R)-1-tert-Butyl 2-Methyl pyrrolidine-1,2-dicarboxylate 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-diMethylethyl) 2-Methyl ester, (2R)- Bok - D - Methyl proline (R)-Boc-pyrrolidine-2-carboxylic acid methyl ester Boc-D-proline methyl ester≥ 99% (HPLC) N-(tert-Butoxycarbonyl)-D-proline Methyl Ester > (2R)-pyrroL idine-1,2-dicarboxyL BOC-D-PRO-OME USP/EP/BP 1-(1,1-Dimethylethyl) 2-methyl (2R)-1,2-pyrrolidinedicarboxylate 1-(tert-butyl) 2-methyl (R)-pyrrolidine-1,2-dicarboxylate Boc-D-methyl proline N-Boc-D-proline methyl ester, 95% O1-tert-Butyl O2-methyl (2R)-pyrrolidine-1,2-dicarboxylate - [B15682] 73323-65-6 Pyrrole&Pyrrolidine&Pyrroline