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ChemicalBook >> CAS DataBase List >>1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol

1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol

1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol Structure
1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol structure
CAS No.
144261-13-2
Chemical Name:
1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol
Synonyms
3,5-(Trans-4-propylcyclohexyl)difluorobenzene;1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol;1,3-DIFLUORO-5-(TRANS-4-PROPYLCYCLOHEXYL)-BENZOL;1,3-difluoro-5-(trans-4-propylcyclohexyl)benzene;Benzene, 1,3-difluoro-5-(trans-4-propylcyclohexyl)-
CBNumber:
CB41448335
Molecular Formula:
C15H20F2
Molecular Weight:
238.32
MDL Number:
MOL File:
144261-13-2.mol
MSDS File:
SDS
Last updated:2026-05-28 02:01:53
Product description Number Pack Size Price
1,3-Difluoro-5-(trans-4-propylcyclohexyl)benzene 97% AS49155 1g $20
1,3-Difluoro-5-(trans-4-propylcyclohexyl)benzene 97% AS49155 5g $32
1,3-Difluoro-5-(trans-4-propylcyclohexyl)benzene 97% AS49155 25g $86
1,3-Difluoro-5-(trans-4-propylcyclohexyl)benzene 97% AS49155 100g $296
1,3-Difluoro-5-(trans-4-propylcyclohexyl)benzene 97% D58365 1g $56.96
Request For Quotation

1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol Properties

Boiling point 279.1±33.0 °C(Predicted)
Density 1.022±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
InChI InChI=1S/C15H20F2/c1-2-3-11-4-6-12(7-5-11)13-8-14(16)10-15(17)9-13/h8-12H,2-7H2,1H3/t11-,12-
InChIKey GHOUEKQRKXYGHJ-HAQNSBGRSA-N
SMILES C1(F)=CC([C@@H]2CC[C@@H](CCC)CC2)=CC(F)=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS49155 1,3-Difluoro-5-(trans-4-propylcyclohexyl)benzene 97% 144261-13-2 1g $20 2026-06-04 Buy
Activate Scientific AS49155 1,3-Difluoro-5-(trans-4-propylcyclohexyl)benzene 97% 144261-13-2 5g $32 2026-06-04 Buy
Activate Scientific AS49155 1,3-Difluoro-5-(trans-4-propylcyclohexyl)benzene 97% 144261-13-2 25g $86 2026-06-04 Buy
Activate Scientific AS49155 1,3-Difluoro-5-(trans-4-propylcyclohexyl)benzene 97% 144261-13-2 100g $296 2026-06-04 Buy
Synthonix D58365 1,3-Difluoro-5-(trans-4-propylcyclohexyl)benzene 97% 144261-13-2 1g $56.96 2026-05-06 Buy
Product number Packaging Price Buy
AS49155 1g $20 Buy
AS49155 5g $32 Buy
AS49155 25g $86 Buy
AS49155 100g $296 Buy
D58365 1g $56.96 Buy

1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol Chemical Properties,Uses,Production

Chemical Properties

Pale yellow liquid

Synthesis

Cyclohexanol, 1-(3,5-difluorophenyl)-4-propyl-

148150-92-9

1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol

144261-13-2

Under nitrogen protection, 132 g of crude 1-(1-hydroxy-4-propylcyclohexyl)-3,5-difluorobenzene was dissolved with 2.99 g of p-toluenesulfonic acid monohydrate in 250 mL of toluene. The reaction mixture was heated and refluxed and stirred for 2 hours while the water generated was removed via a water separator. Upon completion of the reaction, the solution was cooled to room temperature and the organic layer was washed with saturated aqueous sodium bicarbonate and saturated saline in turn. The organic layer was dried over anhydrous sodium sulfate and the solvent was removed by distillation under reduced pressure. The residue was completely dissolved in 280 mL of ethyl acetate, and 7.1 g of 5% palladium/carbon catalyst was added, and the reaction was stirred under hydrogen atmosphere (5 MPa pressure) for 6 hours. At the end of the reaction, the palladium catalyst was removed by filtration and the filtrate was distilled under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography. The purified product was dissolved with 3.39 g of potassium tert-butoxide in 350 mL of DMF and the reaction was stirred at room temperature for 4 hours. After the reaction was completed, water and hexane were added for liquid-liquid separation. The aqueous layer was extracted with hexane, the organic layer and hexane extract were combined and washed with saturated saline. The organic layer was dried over anhydrous sodium sulfate and then distilled under reduced pressure to remove the solvent and further distilled at 206 Pa pressure (boiling point 110 °C to 112 °C) to give 58.05 g of 1-(trans-4-propylcyclohexyl)-3,5-difluorobenzene.

References

[1] Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2001, vol. 364, p. 899 - 910
[2] Patent: US2014/275577, 2014, A1. Location in patent: Paragraph 0104; 0106
[3] Patent: JP6085912, 2017, B2. Location in patent: Paragraph 0063; 0064; 0066

1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol synthesis

148150-92-9
144261-13-2
Synthesis of 1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol from Cyclohexanol, 1-(3,5-difluorophenyl)-4-propyl-

1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol Preparation Products And Raw materials

Raw materials

Cyclohexanol, 1-(3,5-difluorophenyl)-4-propyl- p-Toluenesulfonic acid monohydrate Potassium Ethyl acetate Hydrogen
Recombinant Human Telomerase Toluene N,N-Dimethylformamide

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Preparation Products

1,3-Difluoro-2-iodo-5-(trans-4-propylcyclohexyl)benzene

1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16510 58
Tangshan Moneide Trading Co., Ltd. 		+86-315-8309571 +86-15633399667 sales@moneidechem.com China 574 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		+8617735180244 mike_yan@xuanranglobal.com CHINA 4017 58
Shanghai UCHEM Inc. 		+86-18930848214 +86-021-56762820 sales@myuchem.com China 8886 58
Labnetwork lnc. 		+86-27-50766799 +86-18062016861 contact@labnetwork.com China 19987 58
Aromsyn Co., Ltd. 		+86-0571-85585865 +86-13336024896 CB@aromsyn.com China 19183 58
Allfluoro pharmaceutical co. ltd. 		+86-400-0216110 +86-15958047586 sales@allfluoro.com China 11385 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131956 58
Jin Hesheng New Material Technology (Shandong) Co., LTD 15275330359 15275330359 jinhesheng2021@163.com China 149 58
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2802 65
Supplier Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Tangshan Moneide Trading Co., Ltd. 		58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		58
Shanghai UCHEM Inc. 		58
Labnetwork lnc. 		58
Aromsyn Co., Ltd. 		58
Allfluoro pharmaceutical co. ltd. 		58
Amadis Chemical Company Limited 		58
Jin Hesheng New Material Technology (Shandong) Co., LTD 58
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65

View Lastest Price from 1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol pictures 2026-07-02 1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol
144261-13-2
 $2.20-8.80 1kg 99%min 1000kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

144261-13-2(1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol)Related Search:

3-(Trans-4-propylcyclohexyl)fluorophenyl 1-Fluoro-3-(4-propyl-cyclohexyl)-benzene Benzene, 1-(4-ethylcyclohexyl)-3-fluoro- TRANS-4''-PENTYLCYCLOHEXYL-4-FLUOROBENZENE 1,3-Difluoro-2-iodo-5-(trans-4-propylcyclohexyl)benzene
4-(TRANS-4-PENTYLCYCLOHEXYL)-1-FLUOROBENZENE

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1,3-Difluor-5-(trans-4-propylcyclohexyl)-benzol 3,5-(Trans-4-propylcyclohexyl)difluorobenzene 1,3-difluoro-5-(trans-4-propylcyclohexyl)benzene 1,3-DIFLUORO-5-(TRANS-4-PROPYLCYCLOHEXYL)-BENZOL Benzene, 1,3-difluoro-5-(trans-4-propylcyclohexyl)- 144261-13-2 C15H20F2