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2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid

CAS No.
52916-16-2
Chemical Name:
2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid
Synonyms
2,2-dimethyloxane-4-carboxylic acid;2,2-dimethyl-4-tetrahydropyrancarboxylic acid;2,2-dimethyloxane-4-carboxylic acid - [D86899];2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid;tetrahydro-2,2-dimethyl-2H-pyran-4-carboxylic acid;2H-Pyran-4-carboxylic acid, tetrahydro-2,2-dimethyl-;2,2-dimethyltetrahydro-2H-pyran-4-carboxylic acid(SALTDATA: FREE)
CBNumber:
CB41482128
Molecular Formula:
C8H14O3
Molecular Weight:
158.2
MDL Number:
MFCD00778596
MOL File:
52916-16-2.mol
MSDS File:
SDS
Last updated:2026-05-28 01:23:33
Product description Number Pack Size Price
2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid 159697 100.00mg $85
2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid 159697 250.00mg $128
2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid 159697 1.00g $373
2,2-dimethyloxane-4-carboxylic acid 95% D86899 100mg $90
2,2-dimethyloxane-4-carboxylic acid 95% D86899 250mg $140
More product size

2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid Properties

Melting point 102 °C
Boiling point 261.8±33.0 °C(Predicted)
Density 1.067±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 4.45±0.40(Predicted)
Appearance Off-white to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 159697 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid 52916-16-2 100.00mg $85 2026-05-18 Buy
Matrix Scientific 159697 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid 52916-16-2 250.00mg $128 2026-05-18 Buy
Matrix Scientific 159697 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid 52916-16-2 1.00g $373 2026-05-18 Buy
Synthonix D86899 2,2-dimethyloxane-4-carboxylic acid 95% 52916-16-2 100mg $90 2026-05-06 Buy
Synthonix D86899 2,2-dimethyloxane-4-carboxylic acid 95% 52916-16-2 250mg $140 2026-05-06 Buy
Product number Packaging Price Buy
159697 100.00mg $85 Buy
159697 250.00mg $128 Buy
159697 1.00g $373 Buy
D86899 100mg $90 Buy
D86899 250mg $140 Buy

2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid Chemical Properties,Uses,Production

Synthesis

2,2-dimethyltetrahydro-2H-pyran-4-carbonitrile(SALTDATA: FREE)

60549-63-5

2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid

52916-16-2

The reaction was carried out overnight at reflux in 2N KOH aqueous solution using 2,2-dimethyltetrahydro-2H-pyran-4-carbonitrile (900 mg, 6.47 mmol) as raw material. After completion of the reaction, the reaction mixture was diluted with water and extracted with ethyl acetate and the organic phase was discarded. The aqueous phase was acidified to pH < 7 with 2N HCl solution and subsequently extracted twice with ethyl acetate. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated in vacuum to give the crude product 2,2-dimethyltetrahydro-2H-pyran-4-carboxylic acid (889 mg, 5.62 mmol, 87% yield). The product was characterized by 1H-NMR (400 MHz, DMSO-d6): δ[ppm] 1.13 (s, 3H), 1.14 (s, 3H), 1.26-1.45 (m, 2H), 1.65-1.73 (m, 2H), 2.59 (tt, 1H), 3.54 (td, 1H), 3.60 (ddd, 1H), 12.20 (s, 1H).

References

[1] Patent: WO2016/198374, 2016, A1. Location in patent: Page/Page column 131-132

34941-21-4
52916-16-2
Synthesis of 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid from 2,2-DIMETHYL-TETRAHYDRO-PYRAN-4-CARBALDEHYDE

2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid Preparation Products And Raw materials

Global( 75)Suppliers
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ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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View Lastest Price from 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid pictures 2026-04-17 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid
52916-16-2
$1.60-6.60 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid pictures 2020-01-05 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid
52916-16-2
$1.00 1KG 99% 1kg-1000kg Career Henan Chemical Co

2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid Spectrum

tetrahydro-2,2-dimethyl-2H-pyran-4-carboxylic acid 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid 2,2-dimethyltetrahydro-2H-pyran-4-carboxylic acid(SALTDATA: FREE) 2,2-dimethyl-4-tetrahydropyrancarboxylic acid 2,2-dimethyloxane-4-carboxylic acid 2H-Pyran-4-carboxylic acid, tetrahydro-2,2-dimethyl- 2,2-dimethyloxane-4-carboxylic acid - [D86899] 52916-16-2