N-(4-Methylquinazolin-2-yl)guanidine
- CAS No.
- 716-11-0
- Chemical Name:
- N-(4-Methylquinazolin-2-yl)guanidine
- Synonyms
- 2-guanidino-4-methylquinazoline;2-(4-methylquinazolin-2-yl)guanidine;2-(4-methyl-2-quinazolinyl)guanidine;1-(4-Methylquinazolin-2-yl)guanidine;Guanidine, N-(4-methyl-2-quinazolinyl)-
- CBNumber:
- CB41491184
- Molecular Formula:
- C10H11N5
- Molecular Weight:
- 201.23
- MDL Number:
- MFCD00023908
- MOL File:
- 716-11-0.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P271-P261-P280 |
| target organs | Respiratory system |
| WGK Germany | WGK 3 |
| HS Code | 2933992000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
N-(4-Methylquinazolin-2-yl)guanidine price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0182121 | GMQ 95+% | 716-11-0 | 100mg | $148 | 2026-06-04 | Buy |
| ChemScene | CS-0182121 | GMQ 95+% | 716-11-0 | 250mg | $210 | 2026-06-04 | Buy |
| Apolloscientific | OR303178 | 1-(4-Methylquinazolin-2-yl)guanidine 97% | 716-11-0 | 500mg | $315 | 2026-06-04 | Buy |
| Apolloscientific | OR303178 | 1-(4-Methylquinazolin-2-yl)guanidine 97% | 716-11-0 | 1g | $504 | 2026-06-04 | Buy |
| Matrix Scientific | 080558 | N-(4-Methylquinazolin-2-yl)guanidine | 716-11-0 | 500.00mg | $168 | 2026-05-18 | Buy |
N-(4-Methylquinazolin-2-yl)guanidine Chemical Properties, Uses, Production
Uses
A positively charged guanidium-containing quinazoline that modulates ASIC function by blocking acid-induced maximal peak current as well as by altering ASICs pH dependence for activation and inactivation, enabling a partial, but sustained ASIC3 activation around neutral pH, which is inhibitable by Amiloride. Intraplantar paw injection (10 µL 100 µM) is reported to elicit a pain response in asic3+/+, but not asic3-/-, mice in vivo. GMQ targeting area appears to overlap with Amiloride binding site in the pore region, but is distinct from ASIC calcium binding site.
Biological Activity
Primary Target
ASIC3', 'Reversible: yes
N-(4-Methylquinazolin-2-yl)guanidine Preparation Products And Raw materials
Raw materials
Preparation Products
N-(4-Methylquinazolin-2-yl)guanidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| China Kouting Group Limited | +86 (21) 5811-6473 5811-6475 | sales@koutingchina.com | China | 494 | 60 |
| Credit Asia Chemical Co., Ltd. | +86 (21) 61124340 | China | 9739 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
| Nanjing crow LuNing pharmaceutical technology co., LTD | 13382066392 | CHINA | 4851 | 58 | |
| Shaanxi Istare Biotechnology Co., Ltd. | 18682931470; 18682931470 | 2142355700@qq.com | China | 4412 | 58 |
| Beijing Kemaiqi Medical Technology Co., LTD | 15910349257 15910349257 | 245546570@qq.com | China | 1564 | 58 |
