5-Bromoquinoline
- CAS No.
- 4964-71-0
- Chemical Name:
- 5-Bromoquinoline
- Synonyms
- 5-BromoquinoL;5-BROMOQUINOLINE;5-bronoquinoline;5-bromooquinoline;RARECHEM AK ML 0010;Quinoline, 5-bromo-;5-Bromoquinoline >5-Bromoquinoline,97%;5-Bromoquinoline 97%;5-Bromoquinoline,>98%
- CBNumber:
- CB4149284
- Molecular Formula:
- C9H6BrN
- Molecular Weight:
- 208.05
- MDL Number:
- MFCD00234481
- MOL File:
- 4964-71-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 43-48 °C |
|---|---|
| Boiling point | 105-107°C 1mm |
| Density | 1.5617 (rough estimate) |
| refractive index | 1.6641 (estimate) |
| Flash point | 105-107°C/1mm |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | powder to crystal |
| pka | 3.88±0.12(Predicted) |
| color | White to Light yellow to Green |
| BRN | 115148 |
| InChI | InChI=1S/C9H6BrN/c10-8-4-1-5-9-7(8)3-2-6-11-9/h1-6H |
| InChIKey | CHODTZCXWXCALP-UHFFFAOYSA-N |
| SMILES | N1C2C(=C(Br)C=CC=2)C=CC=1 |
| CAS DataBase Reference | 4964-71-0(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22-22 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29334900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
5-Bromoquinoline price More Price(86)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 714429 | 5-Bromoquinoline 97% | 4964-71-0 | 5g | $190 | 2026-04-30 | Buy |
| TCI Chemical | B3078 | 5-Bromoquinoline >98.0%(GC)(T) | 4964-71-0 | 1g | $51 | 2026-04-30 | Buy |
| Usbiological | 262118 | 5-Bromoquinoline Asreported | 4964-71-0 | 1g | $322 | 2026-06-03 | Buy |
| Usbiological | 262118 | 5-Bromoquinoline Asreported | 4964-71-0 | 2g | $438 | 2026-06-03 | Buy |
| Usbiological | 262118 | 5-Bromoquinoline Asreported | 4964-71-0 | 5g | $538 | 2026-06-03 | Buy |
5-Bromoquinoline Chemical Properties,Uses,Production
Chemical Properties
White solid
Uses
5-Bromoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Preparation
5-Bromoquinoline can be prepared by the reaction of quinoline with dichloromethane and NBS.
Synthesis
611-34-7
4964-71-0
General procedure for the synthesis of 5-bromoquinoline from 5-aminoquinoline: 1. dissolve quinolin-5-amine (3.37 g, 23.38 mmol) in 9 mL of water and 11 mL of hydrogen bromide (48% aqueous solution), and the resulting solution is cooled to 0°C. 2. a solution of sodium nitrite (1.94 g, 28.12 mmol) dissolved in 9 mL of water was added slowly and dropwise. 3. the reaction mixture was stirred at room temperature for 5 minutes. 4. The above solution was added slowly dropwise to a pre-prepared solution of copper (I) bromide (4.02 g, 28.02 mmol dissolved in 23 mL of 48% aqueous hydrogen bromide). 5. The reaction mixture was stirred at 75°C for 2 hours. 6. Upon completion of the reaction, the reaction mixture was alkalized with sodium hydroxide solution. 7. The reaction mixture was extracted twice with ethyl acetate and the organic phases were combined. 8. The organic phase was washed sequentially with water and brine, and then dried over anhydrous sodium sulfate. 9. The desiccant was removed by filtration and the solvent was evaporated under reduced pressure to give 2.98 g (61% yield) of the target product 5-bromoquinoline. Product characterization data: 1H NMR (CDCl3) δ ppm: 7.44-7.63 (m, 2H), 7.84 (d, J = 7.42 Hz, 1H), 8.10 (d, J = 8.24 Hz, 1H), 8.56 (d, J = 8.51 Hz, 1H), 8.94 (br.s., 1H). HPLC/MS (9 min) retention time 5.68 min. Mass spectral data: m/z 208 (M), 210 (M+2).
References
[1] Bioorganic and medicinal chemistry, 2002, vol. 10, # 8, p. 2611 - 2623
[2] Patent: EP2394998, 2011, A1. Location in patent: Page/Page column 16
[3] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 5, p. 1472 - 1476
[4] Journal of Labelled Compounds and Radiopharmaceuticals, 1994, vol. 34, # 10, p. 905 - 913
[5] Patent: US2003/96826, 2003, A1
5-Bromoquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CHANGZHOU MALONG CHEMICALS CO., LTD. | 18651958646 | info@malongchem.com | China | 185 | 58 |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1997 | 58 |
| Changzhou Fourman Chemical Co., Ltd. | 0519-89882557 13912311481 | fourmanchem@163.com | China | 69 | 60 |
| Changzhou Davo Biotech Co., Ltd. | 0519-85165530 13921030872 | davobio@126.com | China | 21 | 58 |
| Changzhou Book Chemical Co., Ltd. | 13606129753 13775119556 | bookchem@126.com | China | 1613 | 62 |
| Wuhan EnTai Technology Development Co,.Ltd | 86-27-82330560 | 2536851935@qq.com | China | 346 | 69 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
View Lastest Price from 5-Bromoquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-02-02 | 5-Bromoquinoline
4964-71-0
|
1KG | 98% HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2025-04-04 | 5-Bromoquinoline
4964-71-0
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd.
|
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2024-04-02 | 5-Bromoquinoline
4964-71-0
|
$1990.00 | 1Kg | 98 | 500 Kg | R&D Scientific Inc. |
-
- 5-Bromoquinoline
4964-71-0
- 98% HPLC
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-Bromoquinoline
4964-71-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 5-Bromoquinoline
4964-71-0
- $1990.00
- 98
- R&D Scientific Inc.
