2,4-Dichloro-5,6-dimethylpyrimidine
- CAS No.
- 1780-32-1
- Chemical Name:
- 2,4-Dichloro-5,6-dimethylpyrimidine
- Synonyms
- 2,4-Dichloro-5,6-dimethylpyrimidine;PyriMidine, 2,4-dichloro-5,6-diMethyl-;2,4-Dichloro-5,6-dimethylpyrimidine ISO 9001：2015 REACH
- CBNumber:
- CB41501252
- Molecular Formula:
- C6H6Cl2N2
- Molecular Weight:
- 177.03
- MDL Number:
- MFCD09910263
- MOL File:
- 1780-32-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933599590 |
2,4-Dichloro-5,6-dimethylpyrimidine price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR926134 | 2,4-Dichloro-5,6-dimethylpyrimidine >98% | 1780-32-1 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR926134 | 2,4-Dichloro-5,6-dimethylpyrimidine >98% | 1780-32-1 | 1g | $45 | 2026-06-04 | Buy |
| Apolloscientific | OR926134 | 2,4-Dichloro-5,6-dimethylpyrimidine >98% | 1780-32-1 | 5g | $217 | 2026-06-04 | Buy |
| Apolloscientific | OR926134 | 2,4-Dichloro-5,6-dimethylpyrimidine >98% | 1780-32-1 | 25g | $1075 | 2026-06-04 | Buy |
| Activate Scientific | AS36138 | 2,4-Dichloro-5,6-dimethylpyrimidine 97% | 1780-32-1 | 1g | $58 | 2026-06-04 | Buy |
2,4-Dichloro-5,6-dimethylpyrimidine Chemical Properties, Uses, Production
Synthesis
26305-13-5
1780-32-1
General procedure for the synthesis of 2,4-dichloro-5,6-dimethylpyrimidine from 5,6-dimethyluracil: A mixture of 5,6-dimethyluracil (4.00 g, 28.5 mmol), phosphorochloride (60 mL, 0.642 mol), and dimethylformamide (0.08 mL, 1.03 mmol) was heated and refluxed for 23 hours at 110 °C. Upon completion of the reaction, the reaction mixture was cooled to room temperature and evaporated. Toluene (80 mL) was added to the residue and the mixture was subsequently concentrated. Cold water (160 mL) containing ice was added to the residue and the mixture was extracted with chloroform (3 x 60 mL). The organic layers were combined, washed with brine (2 x 150 mL), dried over anhydrous sodium sulfate, filtered and concentrated to give 2,4-dichloro-5,6-dimethylpyrimidine as a light yellow solid (4.37 g, 87% yield). The melting point of the product was 68-70 °C. 1H NMR (400 MHz, CDCl3) δ 2.55 (s, 3H), 2.34 (s, 3H). lRMS (ESI+) m/z 177.1.
References
[1] Patent: EP3239143, 2017, A2. Location in patent: Paragraph 0503
[2] Patent: WO2016/22460, 2016, A1. Location in patent: Page/Page column 140-141
[3] Patent: WO2017/66428, 2017, A1. Location in patent: Page/Page column 253
[4] Patent: WO2013/123401, 2013, A1. Location in patent: Page/Page column 40
[5] Nucleosides, Nucleotides and Nucleic Acids, 2004, vol. 23, # 11, p. 1707 - 1721
2,4-Dichloro-5,6-dimethylpyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Nan Jing Dirise Chemcial Co.,LTD | 025-52161033 15312098939 | 2432674894@qq.com | China | 584 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai JONLN Reagent Co., Ltd. | 400-0066400 13621662912 | 422131432@qq.com | China | 9970 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Worldyang Chemical Co.,Ltd. | 021-56795766 | sales@worldyachem.com | China | 9475 | 58 |
| Shanghai YuLue Chemical Co., Ltd. | 021-60345187 13671753212 | lzz841106@aliyun.com | China | 10244 | 55 |
View Latest Price from 2,4-Dichloro-5,6-dimethylpyrimidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 2,4-Dichloro-5,6-dimethylpyrimidine
1780-32-1
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-03-24 | 2,4-Dichloro-5,6-dimethylpyrimidine
1780-32-1
|
$3.00 | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 2,4-Dichloro-5,6-dimethylpyrimidine
1780-32-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2,4-Dichloro-5,6-dimethylpyrimidine
1780-32-1
- $3.00
- 98%
- Career Henan Chemical Co
