Methyl 1-acetyl-1H-indazole-5-carboxylate
- CAS No.
- 239075-26-4
- Chemical Name:
- Methyl 1-acetyl-1H-indazole-5-carboxylate
- Synonyms
- methyl 1-acetylindazole-5-carboxylate;Methyl 1-acetyl-1H-indazole-5-carboxylate;1H-Indazole-5-carboxylic acid, 1-acetyl-, methyl ester
- CBNumber:
- CB41502572
- Molecular Formula:
- C11H10N2O3
- Molecular Weight:
- 218.21
- MDL Number:
- MOL File:
- 239075-26-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Methyl 1-acetyl-1H-indazole-5-carboxylate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | M54296 | Methyl 1-acetyl-1H-indazole-5-carboxylate 95+% | 239075-26-4 | 250mg | $354 | 2026-05-06 | Buy |
| Synthonix | M54296 | Methyl 1-acetyl-1H-indazole-5-carboxylate 95+% | 239075-26-4 | 10g | $360 | 2026-05-06 | Buy |
| Synthonix | M54296 | Methyl 1-acetyl-1H-indazole-5-carboxylate 95+% | 239075-26-4 | 1g | $385 | 2026-05-06 | Buy |
| Synthonix | M54296 | Methyl 1-acetyl-1H-indazole-5-carboxylate 95+% | 239075-26-4 | 5g | $393 | 2026-05-06 | Buy |
| Synthonix | M54296 | Methyl 1-acetyl-1H-indazole-5-carboxylate 95+% | 239075-26-4 | 25g | $400 | 2026-05-06 | Buy |
Methyl 1-acetyl-1H-indazole-5-carboxylate Chemical Properties, Uses, Production
Synthesis
18595-14-7
108-24-7
239075-26-4
Methyl 4-amino-3-methylbenzoate (2.0 g, 12.03 mmol) was dissolved in chloroform (25 mL), and ethanoic anhydride (2.12 g, 30.07 mmol) was added slowly and dropwise at 0 °C. The reaction mixture was stirred at room temperature for 1 h. Potassium acetate (250 mg, 3.61 mmol) and isoamyl nitrite (2.23 mL, 24.06 mmol) were added sequentially. The reaction system was warmed up to 70 °C and stirred at reflux for 18 hours. Upon completion of the reaction, it was diluted by adding excess dichloromethane. The mixture was washed sequentially with saturated aqueous sodium bicarbonate, dried over anhydrous magnesium sulfate and filtered. The filtrate was concentrated under reduced pressure and the residue was purified by column chromatography to afford the intermediate methyl 1-acetyl-1H-indazole-5-carboxylate (1.2 g, 5.50 mmol).
References
[1] Chemical Communications, 2012, vol. 48, # 94, p. 11558 - 11560
[2] Patent: WO2014/129796, 2014, A1. Location in patent: Paragraph 1225-1227
Methyl 1-acetyl-1H-indazole-5-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 1-acetyl-1H-indazole-5-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jinan Trio PharmaTech Co., Ltd. | 0531-88811783 | sales@trio-pharmatech.com | China | 1856 | 62 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Zhen Li Biological Technology Co., Ltd | 021-16621358918; 18516310516;16621358918;13045646768 | zhenlipharma888@163.com | China | 19060 | 58 |
| Wuhan FengyaoTonghui Chemical Products Co., Ltd. | 027-87466105 15377573527 | 2678564200@qq.com | China | 17968 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Hebei Weite Medical Technology Co., Ltd | 13180081292 13180081292 | contact@wetogethermed.com | China | 7715 | 58 |
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| Shaanxi Dideu Newmaterial Co., Ltd. | 029-63373950 17392216152 | 1035@dideu.com | China | 9991 | 58 |
| Shanghai Jianchao Biotechnology Co., LTD | 15021035486 18081542813 | 1804873256@qq.com | China | 6678 | 58 |
