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5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-

CAS No.
54664-55-0
Chemical Name:
5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-
Synonyms
7-Dihydro-5H-cyclopenta[b]pyridine;6,7-Dihydro-5H-[1]pyrindin-4-ylaMine;5H-1-Pyrindine, 4-chloro-6,7-dihydro-;4-CHLORO-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE;5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-;4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 98%;5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- ISO 9001:2015 REACH
CBNumber:
CB41512348
Molecular Formula:
C8H8ClN
Molecular Weight:
153.61
MDL Number:
MFCD11113078
MOL File:
54664-55-0.mol
Last updated:2025-07-24 18:13:52
Product description Number Pack Size Price
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 3H32-5-BT 250mg $92
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 3H32-5-BT 1g $228
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine FC144094 500mg $400
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 95+% 076285 250mg $416
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine FC144094 1g $500
More product size

5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- Properties

Boiling point 234℃
Density 1.241
Flash point 118℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 4.34±0.20(Predicted)
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

HS Code  2933399990

5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
SynQuest Laboratories 3H32-5-BT 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 54664-55-0 250mg $92 2021-12-16 Buy
SynQuest Laboratories 3H32-5-BT 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 54664-55-0 1g $228 2021-12-16 Buy
Biosynth Carbosynth FC144094 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 54664-55-0 500mg $400 2021-12-16 Buy
Matrix Scientific 076285 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 95+% 54664-55-0 250mg $416 2021-12-16 Buy
Biosynth Carbosynth FC144094 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 54664-55-0 1g $500 2021-12-16 Buy
Product number Packaging Price Buy
3H32-5-BT 250mg $92 Buy
3H32-5-BT 1g $228 Buy
FC144094 500mg $400 Buy
076285 250mg $416 Buy
FC144094 1g $500 Buy

5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- Chemical Properties,Uses,Production

Synthesis

6,7-Dihydro-5H-cyclopenta[b]pyridine 1-oxide

90685-58-8

5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-

54664-55-0

6,7-Dihydro-5H-cyclopenta[b]pyridine 1-oxide (2.5 g, 18 mmol) was mixed with phosphoryl chloride (20 mL, 200 mmol). The reaction mixture was stirred at 120 °C for 3 hours. Upon completion of the reaction, the excess POCl3 was removed by distillation under reduced pressure.The residue was diluted with 80 mL of EtOAc and neutralized to pH 7-8 with Na2CO3 solution.After filtration, the aqueous layer was extracted twice (40 mL each) with EtOAc. The organic extracts were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure to give 4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine (2.6 g, 93% yield). LCMS analysis: calculated value of C8H9ClN(M + H)+: m/z = 154.2; measured value: 154.3.

References

[1] Patent: US2014/200216, 2014, A1. Location in patent: Paragraph 0532; 0533
[2] Patent: US2014/200227, 2014, A1. Location in patent: Paragraph 0641; 0642
[3] Patent: WO2016/196244, 2016, A1. Location in patent: Page/Page column 195
[4] Patent: WO2009/19274, 2009, A1. Location in patent: Page/Page column 32
[5] Advanced Synthesis and Catalysis, 2007, vol. 349, # 14-15, p. 2345 - 2352

90685-58-8
54664-55-0
Synthesis of 5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- from 6,7-Dihydro-5H-cyclopenta[b]pyridine 1-oxide

5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- Preparation Products And Raw materials

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View Lastest Price from 5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- pictures 2025-06-25 5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-
54664-55-0
US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
 4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine pictures 2019-07-06 4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine
54664-55-0
US $1.00 / KG 1KG 98% 200KG Career Henan Chemical Co

5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- Spectrum

5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- 4-CHLORO-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE 7-Dihydro-5H-cyclopenta[b]pyridine 6,7-Dihydro-5H-[1]pyrindin-4-ylaMine 5H-1-Pyrindine, 4-chloro-6,7-dihydro- 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 98% 5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- ISO 9001:2015 REACH 54664-55-0 Heterocycle-Pyridine series