5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-
- CAS No.
- 54664-55-0
- Chemical Name:
- 5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-
- Synonyms
- 7-Dihydro-5H-cyclopenta[b]pyridine;6,7-Dihydro-5H-[1]pyrindin-4-ylaMine;5H-1-Pyrindine, 4-chloro-6,7-dihydro-;4-CHLORO-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE;5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-;4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 98%;5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- ISO 9001:2015 REACH
- CBNumber:
- CB41512348
- Molecular Formula:
- C8H8ClN
- Molecular Weight:
- 153.61
- MDL Number:
- MFCD11113078
- MOL File:
- 54664-55-0.mol
Product description | Number | Pack Size | Price |
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine | 3H32-5-BT | 250mg | $92 |
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine | 3H32-5-BT | 1g | $228 |
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine | FC144094 | 500mg | $400 |
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 95+% | 076285 | 250mg | $416 |
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine | FC144094 | 1g | $500 |
More product size |
5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- price More Price(22)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
SynQuest Laboratories | 3H32-5-BT | 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine | 54664-55-0 | 250mg | $92 | 2021-12-16 | Buy |
SynQuest Laboratories | 3H32-5-BT | 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine | 54664-55-0 | 1g | $228 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC144094 | 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine | 54664-55-0 | 500mg | $400 | 2021-12-16 | Buy |
Matrix Scientific | 076285 | 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 95+% | 54664-55-0 | 250mg | $416 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC144094 | 4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine | 54664-55-0 | 1g | $500 | 2021-12-16 | Buy |
5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- Chemical Properties,Uses,Production
Synthesis
![6,7-Dihydro-5H-cyclopenta[b]pyridine 1-oxide](/CAS/GIF/90685-58-8.gif)
90685-58-8
![5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-](/CAS/GIF/54664-55-0.gif)
54664-55-0
6,7-Dihydro-5H-cyclopenta[b]pyridine 1-oxide (2.5 g, 18 mmol) was mixed with phosphoryl chloride (20 mL, 200 mmol). The reaction mixture was stirred at 120 °C for 3 hours. Upon completion of the reaction, the excess POCl3 was removed by distillation under reduced pressure.The residue was diluted with 80 mL of EtOAc and neutralized to pH 7-8 with Na2CO3 solution.After filtration, the aqueous layer was extracted twice (40 mL each) with EtOAc. The organic extracts were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure to give 4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine (2.6 g, 93% yield). LCMS analysis: calculated value of C8H9ClN(M + H)+: m/z = 154.2; measured value: 154.3.
References
[1] Patent: US2014/200216, 2014, A1. Location in patent: Paragraph 0532; 0533
[2] Patent: US2014/200227, 2014, A1. Location in patent: Paragraph 0641; 0642
[3] Patent: WO2016/196244, 2016, A1. Location in patent: Page/Page column 195
[4] Patent: WO2009/19274, 2009, A1. Location in patent: Page/Page column 32
[5] Advanced Synthesis and Catalysis, 2007, vol. 349, # 14-15, p. 2345 - 2352


5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 8026 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49975 | 58 |
View Lastest Price from 5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro- manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
![]() |
2025-06-25 | 5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-
54664-55-0
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
![]() |
2019-07-06 | 4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine
54664-55-0
|
US $1.00 / KG | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro-
54664-55-0
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- 4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine
54664-55-0
- US $1.00 / KG
- 98%
- Career Henan Chemical Co