S-Methyl-L-cysteine
- CAS No.
- 1187-84-4
- Chemical Name:
- S-Methyl-L-cysteine
- Synonyms
- Methylcysteine;H-CYS(ME)-OH;SMC;SMLC;L-Cys（me）-OH;H-L-CYS(ME)-OH;S-METHYL-CYSTEINE;S-Methyl-L-Cys-OH;S-METHYL-L-CYSTEINE;S-MethyI-L-cysteine
- CBNumber:
- CB4154282
- Molecular Formula:
- C4H9NO2S
- Molecular Weight:
- 135.18
- MDL Number:
- MFCD00002612
- MOL File:
- 1187-84-4.mol
- MSDS File:
- SDS
| Melting point | ~240 °C (dec.) |
|---|---|
| alpha | -29.5 º (c=1,water) |
| Boiling point | 300.3±37.0 °C(Predicted) |
| Density | 1.149 (estimate) |
| refractive index | -30 ° (C=2, H2O) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | Aqueous Acid (Slightly, Sonicated), Aqueous Base (Sparingly, Sonicated) |
| form | Solid |
| pka | pK1:8.97 (25°C) |
| color | White to Off-White |
| BRN | 1721675 |
| InChI | InChI=1S/C4H9NO2S/c1-8-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1 |
| InChIKey | IDIDJDIHTAOVLG-VKHMYHEASA-N |
| SMILES | C(O)(=O)[C@H](CSC)N |
| LogP | 0.380 (est) |
| CAS DataBase Reference | 1187-84-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | A34I1H07YM |
| NIST Chemistry Reference | s-Methyl-L-cysteine(1187-84-4) |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H335-H319-H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-24/25-36/37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29309090 | |||||||||
| NFPA 704 |
|
S-Methyl-L-cysteine price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M6626 | S-Methyl-L-cysteine substrate for methionine sulfoxide reductase A | 1187-84-4 | 5g | $106 | 2025-07-31 | Buy |
| Sigma-Aldrich | M6626 | S-Methyl-L-cysteine substrate for methionine sulfoxide reductase A | 1187-84-4 | 25g | $428 | 2025-07-31 | Buy |
| TCI Chemical | M0233 | S-Methyl-L-cysteine >98.0%(T) | 1187-84-4 | 5g | $110 | 2025-07-31 | Buy |
| Sigma-Aldrich | M6626 | S-Methyl-L-cysteine substrate for methionine sulfoxide reductase A | 1187-84-4 | 100g | $1260 | 2025-07-31 | Buy |
| TRC | M294655 | S-Methyl-L-cysteine | 1187-84-4 | 100g | $600 | 2021-12-16 | Buy |
S-Methyl-L-cysteine Chemical Properties,Uses,Production
Chemical Properties
white to light beige fine crystalline powder
Uses
S-Methyl-L-cysteine is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA). It has been studied as a theurapeutic for neurodegenerative diseases including Parkinson′s.
Definition
ChEBI: A cysteine derivative that is L-cysteine in which the hydrogen attached to the sulfur is replaced by a methyl group.
Biological Activity
S-Methyl-L-cysteine (SMLC) is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA). SMLC is naturally present in garlic, cabbage, and turnips and has been studied as a theurapeutic for neurodegenerative diseases including Parkinsonμs.
When used as a dietary supplement in the Drosphilia model of PD, SMLC increases the efficacy of the MRSA catalytic antioxidant system by providing additional substrate available leading to increased resistance to oxidative stress.
Purification Methods
Likely impurities are cysteine and S-methyl-dl-cysteine. Crystallise it from H2O by adding 4volumes of EtOH. It also crystallises from MeOH with m 234-236o(dec), but after sublimation i t has m 267-270o and [] 27D -31.6o (c 1, H2O). [Rinderknecht et al. Helv Chim Acta 41 1, 10 1958, Theodoropoulos Acta Chem Scand 13 383 1959, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1904 1961, Beilstein 4 IV 3145.]
S-Methyl-L-cysteine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 8914 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
| GenicBio Limited | +86-21-37621270 | service@genicbio.com | CHINA | 991 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from S-Methyl-L-cysteine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-01 | S-Methyl-L-cysteine
1187-84-4
|
US $0.00 / removed | 99.87% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-06-13 | S-Methyl-L-cysteine
1187-84-4
|
US $2.00-5.00 / kg | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2019-07-06 | S-Methyl-L-cysteine
1187-84-4
|
US $1.00 / kg | 1 mg | 99% | 100KG | Career Henan Chemical Co |
-
- S-Methyl-L-cysteine
1187-84-4
- US $0.00 / removed
- 99.87%
- TargetMol Chemicals Inc.
-
- S-Methyl-L-cysteine
1187-84-4
- US $2.00-5.00 / kg
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- S-Methyl-L-cysteine
1187-84-4
- US $1.00 / kg
- 99%
- Career Henan Chemical Co
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