Hexa-D-Arginine (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- Hexa-D-Arginine (trifluoroacetate salt)
- Synonyms
- Hexa-D-Arginine (trifluoroacetate salt)
- CBNumber:
- CB415458490
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Hexa-D-Arginine (trifluoroacetate salt) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 36065 | Hexa-D-Arginine (trifluoroacetate salt) ≥95% | 1mg | $32 | 2026-04-30 | Buy | |
| Cayman Chemical | 36065 | Hexa-D-Arginine (trifluoroacetate salt) ≥95% | 5mg | $141 | 2026-04-30 | Buy | |
| Cayman Chemical | 36065 | Hexa-D-Arginine (trifluoroacetate salt) ≥95% | 10mg | $248 | 2026-04-30 | Buy | |
| Cayman Chemical | 36065 | Hexa-D-Arginine (trifluoroacetate salt) ≥95% | 25mg | $542 | 2026-04-30 | Buy |
Hexa-D-Arginine (trifluoroacetate salt) Chemical Properties, Uses, Production
Description
Hexa-D-arginine is an inhibitor of the proprotein convertase furin (Ki = 100 nM).1 It also inhibits West Nile virus nonstructural protein 3 (NS3) protease (Ki = 478 nM). Hexa-D-arginine (1 µg/ml) reduces the proliferation, invasion, and migration of SW 1990 and PaTu 8988 pancreatic cancer cells, as well as decreases the levels of N-cadherin and vimentin and increases E-cadherin levels, markers of the epithelial-to-mesenchymal transition (EMT), in the same cells.2 It improves survival in a rat model of anthrax toxemia induced by the anthrax toxins protective antigen and lethal factor.3WARNING This product is not for human or veterinary use.
References
[1] SERGEY A SHIRYAEV. Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase.[J]. Biochemical Journal, 2006: 503-511. DOI: 10.1042/bj20051374
[2] MENG ZHOU. Furin inhibitor D6R suppresses epithelial-mesenchymal transition in SW1990 and PaTu8988 cells via the Hippo-YAP signaling pathway.[J]. Oncology Letters, 2018: 3192-3196. DOI: 10.3892/ol.2017.7672
[3] MIROSLAV S SARAC. Protection against anthrax toxemia by hexa-D-arginine in vitro and in vivo.[J]. Infection and Immunity, 2004, 72 1: 602-605. DOI: 10.1128/iai.72.1.602-605.2004
Hexa-D-Arginine (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Hexa-D-Arginine (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cayman Chemical Company | -- | sales@caymanchem.com | China | 6808 | 58 |
| Neobioscience Co., Ltd. | -- | info@neobioscience.com | CHINA | 6192 | 58 |
| Supplier | Advantage |
|---|---|
| Cayman Chemical Company | 58 |
| Neobioscience Co., Ltd. | 58 |
